1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. Locked nucleic acid 1

Locked nucleic acid 1 

Cat. No.: HY-111807
Handling Instructions

Locked nucleic acid 1 is a derivative of LNA-type nucleoside.

For research use only. We do not sell to patients.

Locked nucleic acid 1 Chemical Structure

Locked nucleic acid 1 Chemical Structure

CAS No. : 206055-71-2

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Description

Locked nucleic acid 1 is a derivative of LNA-type nucleoside.

Molecular Weight

572.61

Formula

C₃₂H₃₂N₂O₈

CAS No.

206055-71-2

SMILES

O[[email protected]@H]([[email protected]]([[email protected]](N1C(NC(C(C)=C1)=O)=O)O2)OC3)[[email protected]]32COC(C4=CC=C(OC)C=C4)(C5=CC=CC=C5)C6=CC=C(OC)C=C6

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (436.60 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7464 mL 8.7319 mL 17.4639 mL
5 mM 0.3493 mL 1.7464 mL 3.4928 mL
10 mM 0.1746 mL 0.8732 mL 1.7464 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 6.25 mg/mL (10.91 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 6.25 mg/mL (10.91 mM); Clear solution

*All of the co-solvents are provided by MCE.
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Locked nucleic acid 1Locked nucleic acid1Locked nucleic acid-1Nucleoside Antimetabolite/AnalogInhibitorinhibitorinhibit

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Locked nucleic acid 1
Cat. No.:
HY-111807
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