Successful, we will reply to you quickly.OK
Please select the quantity.OK
Your message is being sent, please wait.Close
Send mail failed, please send again!Close
Products are for research use only. Not for human use. We do not sell to patients.
Adefovir dipivoxil Chemical Structure
|Product name: Adefovir dipivoxil|
|Cat. No.: HY-B0255|
Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body.
Target: NRTIs; HBV
Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Adefovir Dipivoxil is used for treatment of hepatitis B and herpes simplex virus infection [1-3]. Adefovir Dipivoxil is approved for the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (primarily ALT) or histologically active disease. Adefovir Dipivoxil is a failed treatment for HIV[3, 4].
|M.Wt||501.47||Storage||Please store the product under the recommended conditions in the Certificate of Analysis.|
|Solvent & Solubility||
10 mM in DMSO
|1 mg||5 mg||10 mg|
|1 mM||1.9941 mL||9.9707 mL||19.9414 mL|
|5 mM||0.3988 mL||1.9941 mL||3.9883 mL|
|10 mM||0.1994 mL||0.9971 mL||1.9941 mL|
. Manolakopoulos, S., et al., Long-term therapy with adefovir dipivoxil in hepatitis B e antigen-negative patients developing resistance to lamivudine. Aliment Pharmacol Ther, 2008. 27(3): p. 266-73.
Bicyclol(SY 801) is a anti-hepatitis drug.
Clevudine is an antiviral drug for the treatment of hepatitis B.
Didanosine(Videx) is a reverse transcriptase inhibitor with an IC50 of 0.49 (mu)M.
Emtricitabine(BW1592) is a nucleoside reverse transcriptase inhibitor (NRTI) for the treatment of HIV infection.
Lagociclovir(MIV-210) is a prodrug of 3(acute)-fluoro-2(acute),3(acute)-dideoxyguanosine with high oral bioavailability in humans and potent activity against HBV.
Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor with an IC50 of 2.7 mM.
Merimepodiba(VX-497) is a novel noncompetitive inhibitor of IMPDH(Inosine monophosphate dehydrogenase).
Osalmid is a ribonucleotide reductase small subunit M2 (RRM2) targeting compound; suppresses ribonucleotide reductase activity with an IC50 of 8.23 (mu)M.
Oxethazaine is a topical anesthetic, in preventing acid-induced esophageal pain.
Telbivudine, a specific inhibitor of hepatitis B virus (HBV) replication, is an antiviral drug used in the treatment of hepatitis B infection.