2. Others
  3. Insecticide
  4. Atractylodin

Atractylodin (Atractydin) is an orally active active ingredient obtained from the rhizome of Atractylodes lancea and A. chinensis. Atractylodin is a natural insecticide. Atractylodin has anti-inflammatory activity.

Para uso exclusivo en investigación. No vendemos a pacientes.

Atractylodin

Atractylodin Estructura química

No. CAS : 55290-63-6

Tamaño Precio Stock Cantidad
Muestra gratis (0.1 - 0.2 mg)   Solicite ahora  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
5 mg En stock
10 mg En stock
25 mg En stock
50 mg En stock
100 mg En stock
200 mg   Obtener un presupuesto  
500 mg   Obtener un presupuesto  

* Seleccione Cantidad antes de agregar artículos.

This product is a controlled substance and not for sale in your territory.

Revisión del cliente

Based on 2 publication(s) in Google Scholar

Other Forms of Atractylodin:

Atractylodin Related Antibodies

Top Publications Citing Use of Products

  • Actividad biológica

  • Pureza y Documentación

  • Referencias

  • Revisión del cliente

Descripciòn

Atractylodin (Atractydin) is an orally active active ingredient obtained from the rhizome of Atractylodes lancea and A. chinensis. Atractylodin is a natural insecticide. Atractylodin has anti-inflammatory activity[1][2][3].

Cellular Effect
Cell Line Type Value Description References
Huh-7 IC50
22.36 μM
Compound: Atractylodin
Cytotoxicity against human Huh-7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against human Huh-7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
[PMID: 38306267]
In Vitro

Atractylodin (50 μM, 48 h) significantly inhibits tumor necrosis factor-α-induced activated B-nuclear factor-κ-light chain enhancer phosphorylation in HCT116 cells[2].
Atractylodin (10, 20, 40 μM, 24 h) alleviates HFD-induced NAFLD by inhibiting hepatocyte sideroptosis[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Atractylodin Related Antibodies

Cell Viability Assay[2]

Cell Line: NCM460, SW480, HCT116
Concentration: 1, 10, 25, 50, 100 μM
Incubation Time: 24 h
Result: Decreased viability at a concentration of 100 µM in HCT116 cells.

Western Blot Analysis[2]

Cell Line: HCT116
Concentration: 50 μM
Incubation Time: 1 h
Result: Inhibited TNF-α-induced phosphorylation of NF-κB p65.
In Vivo

Atractylodin (40 mg/kg intraperitoneally injected for 14 days) can improve the survival rate of mice in a mouse model of colitis induced by sodium dextran sulfate[2].
Atractylodin (20, 40, 80 mg/kg, gavage) alleviates the oxidative stress of HepG2 cells induced by high-fat diet (HFD) and palmitic acid (PA) in mice[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: DSS-Induced Colitis Mouse Model[2]
Dosage: 40 mg/kg
Administration: i.p.
Result: Reduced colitis symptoms and increased survival rate.
Animal Model: NAFLD mice model[3]
Dosage: 20, 40, 80 mg/kg
Administration: i.g.
Result: Reduced the release of ALT, AST, ROS and MDA.
Increased the TG, GSH and SOD.
Peso molecular

182.22

Fòrmula

C13H10O
No. CAS
Appearance

Solid

Color

Light yellow to brown

SMILES

C/C=C/C#CC#C/C=C/C1=CC=CO1
Structure Classification
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvente y solubilidad
In Vitro: 

DMSO : 5.83 mg/mL (31.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4879 mL 27.4394 mL 54.8787 mL
5 mM 1.0976 mL 5.4879 mL 10.9757 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 99.86%

SDS (394 KB)

COA (240 KB) RP-HPLC (224 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.4879 mL 27.4394 mL 54.8787 mL 137.1968 mL
5 mM 1.0976 mL 5.4879 mL 10.9757 mL 27.4394 mL
10 mM 0.5488 mL 2.7439 mL 5.4879 mL 13.7197 mL
15 mM 0.3659 mL 1.8293 mL 3.6586 mL 9.1465 mL
20 mM 0.2744 mL 1.3720 mL 2.7439 mL 6.8598 mL
25 mM 0.2195 mL 1.0976 mL 2.1951 mL 5.4879 mL
30 mM 0.1829 mL 0.9146 mL 1.8293 mL 4.5732 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Atractylodin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Atractylodin55290-63-6AtractydinInsecticideAnti-inflammatoryHCT116HFDDSSInhibitorinhibitorinhibit

Productos vistos recientemente:

Consulta en línea

Your information is safe with us. * Required Fields.

Nombre del producto

  

Requested Quantity *

Nombre del solicitante *

 

Saludo

Direcciòn del E-mail *

 

Número de teléfono *

Department

 

Nombre de la Organizaciòn *

City

Provincia

Country or Region *

      

Observaciones

Consulta para venta a granel

Inquiry Information

Nombre del producto:
Atractylodin
Cat. No.:
HY-N0238
Cantidad:
MCE Japan Authorized Agent:

Revisión del cliente

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Nombre del producto

  

Lot #

Nombre del solicitante *

 

Direcciòn del E-mail *

Número de teléfono

 

Department *

Nombre de la Organizaciòn *

 

Country or Region *

Observaciones

SAFETY DATA SHEET (SDS)

English - EN (394 KB) Français - FR (394 KB) Deutsch - DE (394 KB) Norwegian - NO (394 KB) Español - ES (394 KB) Swedish - SV (394 KB) Italian - IT (394 KB) Korean - KR (394 KB) Portuguese - PT (394 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.