Erythrina sigmoidea Hua

Atractylodin (Atractydin) is an orally active active ingredient obtained from the rhizome of Atractylodes lancea and A. chinensis. Atractylodin is a natural insecticide. Atractylodin has anti-inflammatory activity.

Atractyloside A is an orally active inhibitor of the TLR4/MyD88/NF-κB signaling pathway and also an opener of the mitochondrial permeability transition pore (MPTP). Atractyloside A interferes with the activation of the TLR4/MyD88/NF-κB pathway, thereby inhibiting intestinal inflammatory responses. Atractyloside A reverses mucin synthesis impairment, improves intestinal barrier integrity, and restores homeostasis by altering the composition of the gut microbiota. Atractyloside A can be used in studies related to spleen deficiency diarrhea and myocardial injury.

(-)-Hinesol (Hinesol) is a potent anticancer agent. (-)-Hinesol induces apoptosis and cell cycle arrest at G0/G1 phase. (-)-Hinesol downregulates MEK/ERK pathway and NF-κB pathway and mediates theexpression of cyclin D1, Bax and Bcl-2. (-)-Hinesol has the potential for the research of non–small cell lung cancer.

Fructo-oligosaccharide DP14 is an oligosaccharide that can be isolated from Atractylodes lancea.

Atractylodin (Standard) is the analytical standard of Atractylodin. This product is intended for research and analytical applications. Atractylodin (Atractydin) is an orally active active ingredient obtained from the rhizome of Atractylodes lancea and A. chinensis. Atractylodin is a natural insecticide. Atractylodin has anti-inflammatory activity.

4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate is a polyacetylene compound found in the rhizomes of Atractylodes lancea. 4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate inhibits human pancreatic lipase, with an IC₅₀ of 55.67 μM and 16.7 μg/mL. 4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate can block the digestion of triglycerides by inhibiting the activity of human pancreatic lipase. 4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate can be used in research on obesity.

(1Z)-Atractylodinol, an acetylenes compound, is a weak 5-lipoxygenase (5-LOX) inhibitor with an IC₅₀ of 17.8 μM. (1Z)-Atractylodinol can be used for the study of inflammatory diseases.

12,14-Diacetate-2E,8E,10E-triene-4,6-diyn-1-ol (Compound 26) is a polyacetylene compound that can be isolated from the rhizomes of Atractylodes lancea.

(±)-Sigmoidin A is an active compound. (±)-Sigmoidin A can be used for the research of various biochemical .

Acetylatractylodinol, isolated from Atractylodes lancea, possesses antioxidant activity. Acetylatractylodinol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Atractylodinol, an antimicrobial, is a PRRSV (porcine reproductive and respiratory syndrome virus) inhibitor. Atractylodinol inhibits TGF-β receptor I recycling by binding to vimentin (K_D of 454 nM) and inducing the formation of filamentous aggregates.

(3Z,5E,11E)-3,5,11-Tri-decatriene-7,9-diyne-1,2-diacetate is a human pancreatic lipase inhibitor, with an IC₅₀ of 77.97 μM against human pancreatic lipase. (3Z,5E,11E)-3,5,11-Tri-decatriene-7,9-diyne-1,2-diacetate is applicable to the research of obesity.

(E)-4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate is a polyacetylene found in the rhizomes of Atractylodes lancea. (E)-4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate shows no inhibitory activity against 5-lipoxygenase and COX-1 in in vitro assays at tested concentrations.

(4E,6E,12E)-3-Hydroxy-4,6,12-tetradecatriene-8,10-diyn-1-yl acetate is a polyacetylene found in rhizomes of Atractylodes chinensis. (4E,6E,12E)-3-Hydroxy-4,6,12-tetradecatriene-8,10-diyn-1-yl acetate inhibits RANKL-induced osteoclast differentiation. (4E,6E,12E)-3-Hydroxy-4,6,12-tetradecatriene-8,10-diyn-1-yl acetate can be used for the research of osteoporosis.

(3Z,5E,11E)-3,5,11-Tridecatriene-7,9-diyn-1-ol, 1-acetate is a polyacetylene found in Atractylodes lancea rhizome. (3Z,5E,11E)-3,5,11-Tridecatriene-7,9-diyn-1-ol, 1-acetate inhibits human pancreatic lipase inhibitor with an IC₅₀ of 39.91 μM. (3Z,5E,11E)-3,5,11-Tridecatriene-7,9-diyn-1-ol, 1-acetate can be used for the research of obesity.

(3R,4S,5E,11E)-1,5,11-Tridecatriene-7,9-diyne-3,4-diol (compound CZ-6) is a polyene acetylene compound with significant inhibitory effects on BMM cells.

8-Epiasterolide is a sesquiterpenoid compound isolated from the rhizomes of Atractylodes japonica Koidzumi. 8-Epiasterolide inhibits NO production in LPS (HY-D1056)-treated RAW 264.7 cells. 8-Epiasterolide can be used in the study of inflammatory diseases.

(6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol diacetate is a polyacetylene that can be found in the rhizomes of Atractylodes chinensis, Atractylodes koreana, and Atractylodes japonica.

2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose is an FGFR3 and BRAF binder, and is an isovaleryl sucrose ester that can be found in Atractylodes japonica. 2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose shows low cytotoxicity against cancer cells.

Neocyclomorusin (compound 6) is a flavonoid. Neocyclomorusin can be isolated from Erythrina sigmoidea. Neocyclomorusin inhibits the CCRF-CEM cell line with an IC50 value of 59.02 μM.