4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate
4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate is a polyacetylene compound found in the rhizomes of Atractylodes lancea. 4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate inhibits human pancreatic lipase, with an IC50 of 55.67 μM and 16.7 μg/mL. 4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate can block the digestion of triglycerides by inhibiting the activity of human pancreatic lipase. 4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate can be used in research on obesity.
For research use only. We do not sell to patients.
- CAS No.: 23414-61-1
- Formula: C18H20O4
- Molecular Weight:300.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate (compound 5) (10 min pre-incubation; 30 min substrate reaction at 37°C) inhibits recombinant human pancreatic lipase with an IC50 of 55.67 μM and 16.7 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 23414-61-1
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Molecular Weight 300.35
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Formula C18H20O4
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SMILES
C/C=C/C#CC#C/C=C/C=C/C(OC(C)=O)CCOC(C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)