Atractylodinol
Based on 1 Customer Validation
Atractylodinol, an antimicrobial, is a PRRSV (porcine reproductive and respiratory syndrome virus) inhibitor. Atractylodinol inhibits TGF-β receptor I recycling by binding to vimentin (KD of 454 nM) and inducing the formation of filamentous aggregates.
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- Pureza : 99.60%
- No. CAS: 61642-89-5
- Fòrmula: C13H10O2
- Peso molecular:198.22
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Almacenamiento:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Actividad biológica
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Chemical Information
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Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BMDM | IC50 |
0.64 μM
Compound: 32
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Anti-osteoclastogensis activity C57BL/6 mouse bone marrow macrophages assessed as inhibition of RANKL-induced osteoclastogenesis and measured after 5 days in presence of M-CSF by TRAP staining based assay
Anti-osteoclastogensis activity C57BL/6 mouse bone marrow macrophages assessed as inhibition of RANKL-induced osteoclastogenesis and measured after 5 days in presence of M-CSF by TRAP staining based assay
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[PMID: 35324175] |
Chemical Information
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No. CAS 61642-89-5
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Appearance Solid
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Peso molecular 198.22
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Fòrmula C13H10O2
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Color Yellow to brown
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SMILES
OC/C=C/C#CC#C/C=C/C1=CC=CO1
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Structure Classification
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Pureza y Documentación
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Ficha de datos (264 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Mengjiao Hao, et al. Atractylodinol prevents pulmonary fibrosis through inhibiting TGF-β receptor 1 recycling by stabilizing vimentin. Mol Ther. 2023 Oct 4;31(10):3015-3033. [Content Brief]
[2]. Alyssa B Evans, et al. Identification and characterization of small molecule inhibitors of porcine reproductive and respiratory syndrome virus. Antiviral Res. 2017 Oct:146:28-35. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Atractylodinol Related Classifications
HY-N2092 Related Classifications
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