61642-89-5
61642-89-5
Chemical Structure
Atractylodinol
- CAS No.: 61642-89-5
- Formula:C13H10O2
- Molecular Weight:198.22
IUPAC Name: (2E,8E)-9-(furan-2-yl)nona-2,8-dien-4,6-diyn-1-ol
InChIKey: JPWHLNBWBPJJJN-PDTNFJSOSA-N
SMILES: OC/C=C/C#CC#C/C=C/C1=CC=CO1
Biological Activity: Atractylodinol, an antimicrobial, is a PRRSV (porcine reproductive and respiratory syndrome virus) inhibitor. Atractylodinol inhibits TGF-β receptor I recycling by binding to vimentin (KD of 454 nM) and inducing the formation of filamentous aggregates[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Atractylodinol | 99.60% | Atractylodinol, an antimicrobial, is a PRRSV (porcine reproductive and respiratory syndrome virus) inhibitor. Atractylodinol inhibits TGF-β receptor I recycling by binding to vimentin (KD of 454 nM) and inducing the formation of filamentous aggregates. | ||||||||||||||||||||
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References
- [1]. Mengjiao Hao, et al. Atractylodinol prevents pulmonary fibrosis through inhibiting TGF-β receptor 1 recycling by stabilizing vimentin. Mol Ther. 2023 Oct 4;31(10):3015-3033. [Content Brief]
- [2]. Alyssa B Evans, et al. Identification and characterization of small molecule inhibitors of porcine reproductive and respiratory syndrome virus. Antiviral Res. 2017 Oct:146:28-35. [Content Brief]
Keywords
