2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose
2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose is an FGFR3 and BRAF binder, and is an isovaleryl sucrose ester that can be found in Atractylodes japonica. 2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose shows low cytotoxicity against cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 150302-84-4
- Formula: C37H62O16
- Molecular Weight:762.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
FGFR3 |
Braf |
In Vitro
2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose (Compound 11) (0-100 μM; 48 h) does not exhibit cytotoxic activity against HCT-116 or A549 cells, with IC50 values >50 μM[1].
2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose binds weakly to FGFR3 and BRAF proteins, with binding energies of -6.87 kcal/mol (FGFR3) and -4.68 kcal/mol (BRAF)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HCT-116, A549
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Concentration:0-100 μM
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Incubation Time:48 h
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Result:Showed no inhibitory activity against HCT-116 and A549 cells, with IC50 values greater than 50 μM.
Chemical Information
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CAS No. 150302-84-4
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Molecular Weight 762.88
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Formula C37H62O16
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SMILES
OC[C@@]1([C@H]([C@@H]([C@H](O1)COC(CC(C)C)=O)OC(CC(C)C)=O)OC(CC(C)C)=O)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)OC(CC(C)C)=O)O)OC(CC(C)C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose Related Classifications
HY-N13841 Related Classifications
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