1. Alkaloids
  2. L-(+)-Abrine

L-(+)-Abrine (Synonyms: L-Abrine; L-N-Methyltryptophan; N-α-Methyl-L-tryptophan)

Cat. No.: HY-N1436 Purity: 99.76%
Handling Instructions

L-(+)-Abrine, a lethal albumin found in Abrus precatorius seeds, is an acute toxic alkaloid and chemical marker for abrin.

For research use only. We do not sell to patients.

L-(+)-Abrine Chemical Structure

L-(+)-Abrine Chemical Structure

CAS No. : 526-31-8

Size Price Stock Quantity
50 mg USD 50 In-stock
Estimated Time of Arrival: December 31
100 mg USD 80 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Protocol

  • Purity & Documentation

  • References

  • Customer Review


L-(+)-Abrine, a lethal albumin found in Abrus precatorius seeds, is an acute toxic alkaloid and chemical marker for abrin.

In Vitro

L-(+)-Abrine is a marker for abrin poisoning. A strong indication for abrin poisoning is the presence of the chemical maker L-(+)-Abrine, which can survive metabolism in significant amounts making it detectable in human urine[1].

In Vivo

Abrin is a toxic protein found in the jequirity seed. L-(+)-Abrine (L-Abrine) is also found in the jequirity seed and can be used as a biomarker for abrin exposure. An animal study is designed to monitor the excretion and recovery of L-(+)-Abrine in 20 rats. The animals are exposed to one of three concentrations of L-(+)-Abrine, a single high concentration of L-tryptophan, or no agent (control). The low L-(+)-Abrine dose corresponds to 0.63 LD50 i.p. abrin in mice, assuming a concentration ratio of 1:4 of abrin to L-(+)-Abrine and an LD50 for abrin of 20 μg/kg. The mid and high L-(+)-Abrine (250 and 400 μg/kg) doses are included to ensure that the target analyte can be detected and tracked over the course of the experiment[2].

Molecular Weight







O=C(O)[[email protected]](CC1=CNC2=CC=CC=C12)NC


Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 2 mg/mL (9.16 mM; ultrasonic and adjust pH to 10 with NaOH)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5819 mL 22.9095 mL 45.8190 mL
5 mM 0.9164 mL 4.5819 mL 9.1638 mL
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
Animal Administration

Twenty male Wistar rats, approximately 6-7 weeks of age and weighing approximately 175-200 g upon receipt, are used. A total of 12 rats are dosed intramuscularly with L-(+)-Abrine at 0.63, 3.13, and 5 times the expected Abrin LD50 of 20 μg/kg. Although no toxin is used here, the concentration of the biomarker is increased by a factor of 4 to estimate an equivalent level of toxin, assuming that Labrine is present in rosary peas at a concentration four times greater that the toxin abrin. A total of 12 rats are dosed intramuscularly with L-(+)-Abrine: four at approximately 50 μg/kg body weight (bw), four at 250 μg/kg bw, and four at 400 μg/kg bw. Four control rats are dosed with water, which is the vehicle for all dosing experiments. Another four rats are dosed intraperitoneally with 20,000 μg/kg L-tryptophan to verify that endogenous L-tryptophan is not metabolized to L-(+)-Abrine[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2



Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name



Applicant name *


Email address *

Phone number *


Organization name *

Country or Region *


Requested quantity *


Bulk Inquiry

Inquiry Information

Product name:
Cat. No.:
MCE Japan Authorized Agent: