1. Natural Products
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  3. Umbelliferae
  4. Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. ex Franch. e

Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. ex Franch. e

Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. ex Franch. e (10):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0285
    Imperatorin 482-44-0 98.00%
    Imperatorin is an effective of NO synthesis inhibitor (IC50=9.2 μmol), which also is a BChE inhibitor (IC50=31.4 μmol). Imperatorin is a weak agonist of TRPV1 with EC50 of 12.6±3.2 μM.
  • HY-N2110
    Phellopterin 2543-94-4 99.94%
    Phellopterin is a natural product isolated from P. trifoliata. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium.
  • HY-N0286
    Isoimperatorin 482-45-1 98.93%
    Isoimperatorin is a methanolic extract of the roots of Angelica dahurica shows significant inhibitory effects on acetylcholinesterase (AChE) with the IC50 of 74.6 μM.
  • HY-N6022
    Byakangelicin 482-25-7 99.96%
    Byakangelicin, one of the active compounds found in the roots of Angelica gigas, can serve as a modulator to improve brain accumulation of diverse active compounds (Umb, Cur, and Dox) and enhance therapeutic effects. Byakangelicin is likely to increase the expression of all PXR target genes (such as MDR1) and induce a wide range of drug-drug interactions. Byakangelicin can inhibit the effects of sex hormones, it may increase the catabolism of endogenous hormones.
  • HY-N0074
    Byakangelicol 26091-79-2 99.51%
    Byakangelicol, isolated from Angelica dahurica, inhibits interleukin-1beta (IL-1beta) -induced prostaglandin E2 (PGE2) release in A549 cells mediated by suppression of cyclooxygenase-2 (COX-2) expression and the activity of COX-2 enzyme. Byakangelicol has therapeutic potential as an anti-inflammatory drug on airway inflammation.
  • HY-N9535
    tert-OMe-byakangelicin 79638-04-3
    tert-OMe-byakangelicin is a coumarin that can enhances the adrenaline-induced lipolytic effect and inhibits insulin-stimulated triglyceride synthesis from glucose in fat cells.
  • HY-N9532
    Isobyakangelicol 35214-81-4
    Isobyakangelicol is a coumarin that can be found in the roots of Angelica dahurica. Isobyakangelicol inhibits the growth of HeLa and HepG2 cells, with IC50s of 70.04 μM and 17.97 μM.
  • HY-N4052
    Heraclenol 31575-93-6
    Heraclenol, a coumarin, is isolated from the fruits of Angelica lucida, and exhibits antibacterial activities.
  • HY-N2622
    Oxypeucedanin hydrate 2643-85-8 ≥98.0%
    Oxypeucedanin hydrate ((+)-Oxypeucedanin hydrate) is a natural product isolated from D. anethifolia. Prangol exhibits mild toxicity on fibroblasts and parental lymphoma cells.
    Oxypeucedanin hydrate
  • HY-N2356
    Apiosylskimmin 103529-94-8
    Apiosylskimmin (Adicardin), a coumarin isolated from Hydrangea macrophylla, has anti-chronic renal failure activity .