- Natural Products
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- Umbelliferae
- Centella asiatica (L.) Urb.
Centella asiatica (L.) Urb.
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Centella asiatica (L.) Urb. (21)
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- Formula: C48H78O19
- Molecular Weight: 959.12
Asiaticoside, a trisaccaride triterpene from Centella asiatica, suppresses TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts; Asiaticoside shows antioxidant, anti-inflammatory, and anti-ulcer properties.
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- Formula: C30H48O5
- Molecular Weight: 488.70
Asiatic acid, a pentacyclic triterpene found in Centella asiatica (Centella asiatica), has anticancer activity. Asiatic acid induces apoptosis in melanoma cells and has barrier protective effects on human aortic endothelial cells (HAEC). Asiatic acid also has anti-inflammatory activity and inhibits tumor necrosis factor (TNF)-α-induced endothelial barrier dysfunction. Asiatic acid also inhibits NLRP3 inflammasome activation and NF-κB pathway, effectively inhibits inflammation in rats, and has neuroprotective effects in rat spinal cord injury (SCI) model.
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- Formula: C48H78O20
- Molecular Weight: 975.12
Madecassoside is a pentacyclic triterpene isolated from Centella asiatica and has anti-inflammatory properties. Antioxidant and anti-aging effects. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica. Madecassoside is orally active and has inhibitory properties against inflammation, oxidation, apoptosis and autophagy. Madecassosid inhibits activities of p38 MAPK and NF-kB, exhibits an anti-apopototic property, activates Nrf2 expression to reduce the neurotoxicity. Madecassoside can be used in endocrine diseases, cardiovascular diseases, skin diseases and other diseases.
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- Formula: C30H48O6
- Molecular Weight: 504.70
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- Formula: C₄₈H₇₈O₂₀
- Molecular Weight: 975.12
Madecassoside (Standard) is the analytical standard of Madecassoside. This product is intended for research and analytical applications. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica and has anti-inflammatory properties. Antioxidant and anti-aging effects. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica. Madecassoside is orally active and has inhibitory properties against inflammation, oxidation, apoptosis and autophagy. Madecassosid inhibits activities of p38 MAPK and NF-kB, exhibits an anti-apopototic property, activates Nrf2 expression to reduce the neurotoxicity[10]. Madecassoside can be used in endocrine diseases, cardiovascular diseases, skin diseases and other diseases.
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- Formula: C₄₈H₇₈O₁₉
- Molecular Weight: 959.12
Asiaticoside (Standard) is the analytical standard of Asiaticoside. This product is intended for research and analytical applications. Asiaticoside, a trisaccaride triterpene from Centella asiatica, suppresses TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts; Asiaticoside shows antioxidant, anti-inflammatory, and anti-ulcer properties.
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- Formula: C₃₀H₄₈O₅
- Molecular Weight: 488.70
Asiatic acid (Standard) is the analytical standard of Asiatic acid. This product is intended for research and analytical applications. Asiatic acid, a pentacyclic triterpene found in Centella asiatica (Centella asiatica), has anticancer activity. Asiatic acid induces apoptosis in melanoma cells and has barrier protective effects on human aortic endothelial cells (HAEC). Asiatic acid also has anti-inflammatory activity and inhibits tumor necrosis factor (TNF)-α-induced endothelial barrier dysfunction. Asiatic acid also inhibits NLRP3 inflammasome activation and NF-κB pathway, effectively inhibits inflammation in rats, and has neuroprotective effects in rat spinal cord injury (SCI) model.
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- Formula: C48H78O20
- Molecular Weight: 975.12
Asiaticoside B is a 9,19-cycloartane triterpene glycoside found in Actaea asiatica. Asiaticoside B has cytotoxicity against HepG2 and MCF-7 cancer cells with IC50 values of 9.74 µM and 8.32 µM, respectively.
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- Formula: C₃₀H₄₈O₆
- Molecular Weight: 504.70
Madecassic acid (Standard) is the analytical standard of Madecassic acid. This product is intended for research and analytical applications. Madecassic acid is isolated from Centella asiatica (Umbelliferae). Madecassic acid has anti-inflammatory properties caused by iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-κB activation in RAW 264.7 macrophage cells.
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- Formula: C48H78O20
- Molecular Weight: 975.12
Asiaticoside B (Standard) is the analytical standard of Asiaticoside B (HY-N5052). This product is intended for research and analytical applications. Asiaticoside B is a 9,19-cycloartane-type triterpene glycoside. Asiaticoside B induces cytotoxicity in liver cancer and breast cancer cells. Asiaticoside B alleviates 6-OHDA-induced neuronal cell damage. Asiaticoside B can be used in studies related to liver cancer, breast cancer and Parkinson's disease.
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- Formula: C48H78O19
- Molecular Weight: 959.12
Isoasiaticoside is a pentacyclic triterpene saponin that can be isolated from Centella asiatica. Isoasiaticoside has potential neuroprotective effects in the 6-OHDA (HY-B1081)-induced PC12 cell model.
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- Formula: C48H78O19
- Molecular Weight: 959.12
Centellasaponin A (compound 10) is a pentacyclic triterpene saponin isolated from the methanolic extract of Centella asiatica.
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- Formula: C48H78O19
- Molecular Weight: 959.12
Scheffoleoside A is a neuroprotective agent can be derived from Centella asiatica. Scheffoleoside A exhibits moderate activity in inhibiting 6-OHDA-induced cytotoxicity.
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- Formula: C12H10O5
- Molecular Weight: 234.20
6-Formyllimetin is a natural product isolated from the root bark of T. asiatica LAM.
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- Formula: C16H18O5
- Molecular Weight: 290.31
Toddanone, a coumarin, can be isolated from the root of Toddalia asiatica.
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- Formula: C16H18O5
- Molecular Weight: 290.31
(-)-Toddanol, a coumarin, can be isolated from the root of Toddalia asiatica.
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- Formula: C16H19ClO5
- Molecular Weight: 326.77
(+)-6-(3-Chloro-2-hydroxy-3-methylbutyl)-5,7-dimethoxycoumarin is a nature product that could be isolated form the root bark of Toddalia asiatica (L.) LAM.
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- Formula: C28H32O14
- Molecular Weight: 592.55
Margaritene is a natural product.
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- Formula: C28H32O14
- Molecular Weight: 592.55
Isomargaritene is a natural product.
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