1. Immunology/Inflammation
    Apoptosis
  2. NO Synthase
    COX
    TNF Receptor
    Interleukin Related
  3. Madecassic acid

Madecassic acid 

Cat. No.: HY-N0569
Handling Instructions

Madecassic acid is isolated from Centella asiatica (Umbelliferae). Madecassic acid has anti-inflammatory properties caused by iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-κB activation in RAW 264.7 macrophage cells.

For research use only. We do not sell to patients.

Madecassic acid Chemical Structure

Madecassic acid Chemical Structure

CAS No. : 18449-41-7

Size Price Stock
5 mg USD 50 Ask For Quote & Lead Time
10 mg USD 80 Ask For Quote & Lead Time
20 mg USD 140 Ask For Quote & Lead Time

* Please select Quantity before adding items.

Top Publications Citing Use of Products

View All COX Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Madecassic acid is isolated from Centella asiatica (Umbelliferae). Madecassic acid has anti-inflammatory properties caused by iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-κB activation in RAW 264.7 macrophage cells[1].

IC50 & Target

COX-2

 

TNF-α

 

IL-1β

 

IL-6

 

Molecular Weight

504.70

Formula

C₃₀H₄₈O₆

CAS No.

18449-41-7

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Madecassic acidNO SynthaseCOXTNF ReceptorInterleukin RelatedNitric oxide synthasesNOSCyclooxygenaseTumor Necrosis Factor ReceptorTNFRILCentellaasiaticaNF-κBRAW264.7macrophagecellsInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product name:
Madecassic acid
Cat. No.:
HY-N0569
Quantity:
MCE Japan Authorized Agent: