2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W014394
    Vanillyl butyl ether 82654-98-6 99.75%
    Vanillyl butyl ether is a major contributor to the characteristic flavor and fragrance of vanilla. Vanillyl butyl ether is one of the eco-friendly and nontoxic substances. Vanillyl butyl ether exhibits mutually inhibitory effects on mammalian TRPV1 and TRPM8 channels. Vanillyl butyl ether shows repellency activity against Tribolium castaneum, T. confusum and L. bostrychophila. Vanillyl butyl ether acts as a mild warming agent, providing a warming sensation and enhancing blood circulation.
    Vanillyl butyl ether
  • HY-W014665
    N-Phthaloylglycine 4702-13-0 99.95%
    N-Phthaloylglycine (Phthaloyl glycine) is a Type II fragmentary hapten (FX-type) with antimicrobial activity. N-Phthaloylglycine acts against Candida albicans, Escherichia coli, and Staphylococcus epidermidis. N-Phthaloylglycine can be used for the research of fungal and bacterial infection.
    N-Phthaloylglycine
  • HY-W016149
    4,5-Dichloro-3H-1,2-dithiol-3-one 1192-52-5 98.0%
    4,5-Dichloro-3H-1,2-dithiol-3-one (Dichloro-1,2-dithiacyclopentenone) is an E. coli FabH inhibitor (IC50: 2.9 µM). 4,5-Dichloro-3H-1,2-dithiol-3-one can be used as a slimicide in the manufacture of food-contact paper and paperboard .
    4,5-Dichloro-3H-1,2-dithiol-3-one
  • HY-W016407
    Methyl 3,4-dihydroxyphenylacetate 25379-88-8 99.82%
    Methyl 3,4-dihydroxyphenylacetate is a potent enterovirus 71 (EV71) infection inhibitor. Methyl 3,4-dihydroxyphenylacetate inhibits EV71 replication in rhabdomyosarcoma (RD) cells.
    Methyl 3,4-dihydroxyphenylacetate
  • HY-W016867
    4-Chlorosalicylic acid 5106-98-9 ≥98.0%
    4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibits monophenolase and diphenolase activity with IC50s of 1.89 mM and 1.10 mM. Potent antimicrobial activity. Against E. coli with the MIC of 250 μg/mL and with the MBC of 500 μg/mL.
    4-Chlorosalicylic acid
  • HY-W017087
    1,2,4-Trimethoxybenzene 135-77-3 98%
    1,2,4-Trimethoxybenzene is an orally active NLRP3 selective inhibitor. 1,2,4-Trimethoxybenzene can markedly suppress Nigericin (HY-127019) or ATP (HY-B2176)-induced NLRP3 inflammasome activation, thus decreasing caspase-1 activation and IL-1β secretion. 1,2,4-Trimethoxybenzene specifically inhibits the activation of NLRP3 inflammasome without affecting absent in melanoma 2 (AIM2) inflammasome activation. 1,2,4-Trimethoxybenzene inhibits oligomerization of the apoptosis-associated speck-like protein containing a CARD (ASC) and protein-protein interaction between NLRP3 and ASC, thus blocking NLRP3 inflammasome assembly. 1,2,4-Trimethoxybenzene can be used for the study of experimental autoimmune encephalomyelitis (EAE), multiple sclerosis, and type 2 diabetes.
    1,2,4-Trimethoxybenzene
  • HY-W019829
    Polyphyllin C 76296-71-4 98%
    Polyphyllin C (compound 2) is a spirostanol saponin. Polyphyllin C exhibits mild (IC50=36.87 µM) activities against the tyrosinase and moderate (IC50=1.59 µg/mL) antileishmanial activities.
    Polyphyllin C
  • HY-W028047
    JFD01307SC 51070-56-5 98.0%
    JFD01307SC is a glutamine synthetase inhibitor and anti-tuberculosis agent. JFD01307SC acts as a mimic of L-Glutamate and thus target enzymes involved in glutamine biosynthesis.
    JFD01307SC
  • HY-W039169
    4-Chloroguaiacol 16766-30-6 99.89%
    4-Chloroguaiaco (4-Chloro-2-methoxyphenol) is a phenol derivative, with antimicrobial activity. 4-Chloroguaiaco shows inhibition against S. aureus and E. coli with MICs of both 110 μg/mL.
    4-Chloroguaiacol
  • HY-W040156
    Oxadixyl 77732-09-3 98%
    Oxadixyl is a fungicide with activity that inhibits the growth of fungi. Oxadixyl was tested during the malic fermentation of red wine, where its concentration may be affected. The biological activity of Oxadixyl helps to evaluate its effect on microorganisms during the winemaking process.
    Oxadixyl
  • HY-W049875
    Nitroxynil 1689-89-0 98.92%
    Nitroxynil, anthelmintic agent, is active against parasites in both adult and immature stages. Nitroxynil is widely used for the research of infection of Fasciola hepatica.
    Nitroxynil
  • HY-W074648
    Antibacterial agent 18 1239602-35-7
    Antibacterial agent 18 is a multi-arm AIE molecule extracted from patent CN110123801A, compound 23. Antibacterial agent 18 can be used for resisting Gram-positive and Gram-negative bacteria. Antibacterial agent 18 can be conjugated in the cell wall of rigid arm configuration insertion bacterium, and block cell wall turns sugar and turns peptide process, to inhibit or kill bacterium.
    Antibacterial agent 18
  • HY-W075248
    m-THPP 22112-79-4 98%
    m-THPP (Tetra(3-hydroxyphenyl)porphyrin; 3-THPP) is a photosensitizer. m-THPP can weakly induce ROS production and shows antitumor and antibacterial activity. m-THPP can be used for the research of photodynamic therapy (PDT).
    m-THPP
  • HY-W078844
    PfDHODH-IN-2 425629-94-3 99.83%
    PfDHODH-IN-2, a dihydrothiophenone derivative (Compound 11), is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor with an IC50 of 1.11 µM. PfDHODH-IN-2 acts as an antimalarial agent and can be used for the research of malaria.
    PfDHODH-IN-2
  • HY-W097570
    Sulfamonomethoxine sodium 38006-08-5 99.88%
    Sulfamonomethoxine sodium is an orally active broad-spectrum synthetic sulfonamide antibiotic that inhibits dihydropteroate synthetase. Sulfamonomethoxine sodium increases blood glucose levels, induces anxiety-related activities and impairs spatial learning and memory. Sulfamonomethoxine sodium can be used for the research of anxiety, spatial memory impairment, colisepticemia, salmonellosis, and staphylococcus infection.
    Sulfamonomethoxine sodium
  • HY-W099569
    Zinc stearate 557-05-1 98%
    Zinc stearate is a metal stearate that acts as a preservative, bactericide, fungicide, and larvicide. Zinc stearate inhibits larval reproduction in animal feces. Zinc stearate exhibits extremely low systemic toxicity. Zinc stearate is a common component of pharmaceutical excipients, lubricants, mold release agents, polymer stabilizers, and coating matting agents.
    Zinc stearate
  • HY-W102349
    S-Methyl thioacetate 1534-08-3 98%
    S-Methyl thioacetate is a toxicant with fumigant activity, can be found in emissions from Bacillus oshimensis, Burkholderia gladioli, Burkholderia cepacia, and Pseudomonas oryzihabitans. S-Methyl thioacetate exerts fumigant toxicity against Caenorhabditis elegans and root-knot nematode Meloidogyne incognita. S-Methyl thioacetate functions as a bacterial volatile organic compound. S-Methyl thioacetate can be used for the research of plant-parasitic nematode infection.
    S-Methyl thioacetate
  • HY-W112166
    (E/Z)-4,4'-Dicyanostilbene 6292-62-2 98.34%
    (E/Z)-4,4'-Dicyanostilbene is the isomer of 4,4'-Dicyanostilbene (HY-W112166A), and can be used as an experimental control. 4,4'-Dicyanostilbene (compound 43) is a potent antimalarial agent against the Dd2 strain, with an EC50 of 27 nM. 4,4'-Dicyanostilbene exhibits in vivo efficacy against methicillin-resistant Staphylococcus aureus (MRSA).
    (E/Z)-4,4'-Dicyanostilbene
  • HY-W127493
    1-Hexacosanol 506-52-5 98.0%
    1-Hexacosanol can be used as an inhibitor of acetylcholinesterase (AChE). 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects.
    1-Hexacosanol
  • HY-W141788
    N-Butyryl-DL-homocysteine thiolactone 39837-08-6 98%
    N-Butyryl-DL-homocysteine thiolactone is an N-acyl homoserine lactone (AHL) analogue. AHLs are potent inhibitors of biofilm formation and virulence factors, and has been used for degrading microbial communities, reducing bacterial pathogenicity.
    N-Butyryl-DL-homocysteine thiolactone
Cat. No. Product Name / Synonyms Application Reactivity