m-THPP
Based on 1 Customer Validation
m-THPP (Tetra(3-hydroxyphenyl)porphyrin; 3-THPP) is a photosensitizer. m-THPP can weakly induce ROS production and shows antitumor and antibacterial activity. m-THPP can be used for the research of photodynamic therapy (PDT).
For research use only. We do not sell to patients.
- CAS No.: 22112-79-4
- Formula: C44H30N4O4
- Molecular Weight:678.73
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | IC50 |
25.69 nM
Compound: mTHPC
|
Photocytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability preincubated for 24 hrs followed by washout and 1 J/cm2 light irradiation for 24 hrs by resazurin reduction assay
Photocytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability preincubated for 24 hrs followed by washout and 1 J/cm2 light irradiation for 24 hrs by resazurin reduction assay
|
[PMID: 37634417] |
| MDA-MB-231 | IC50 |
3.31 μM
Compound: mTHPC
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Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs under dark condition by resazurin reduction assay
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs under dark condition by resazurin reduction assay
|
[PMID: 37634417] |
| NIH3T3 | IC50 |
12.53 nM
Compound: mTHPC
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Photocytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability preincubated for 24 hrs followed by washout and 1 J/cm2 light irradiation for 24 hrs by resazurin reduction assay
Photocytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability preincubated for 24 hrs followed by washout and 1 J/cm2 light irradiation for 24 hrs by resazurin reduction assay
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[PMID: 37634417] |
| NIH3T3 | IC50 |
9.16 μM
Compound: mTHPC
|
Cytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability incubated for 24 hrs under dark condition by resazurin reduction assay
Cytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability incubated for 24 hrs under dark condition by resazurin reduction assay
|
[PMID: 37634417] |
Chemical Information
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CAS No. 22112-79-4
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Appearance Solid
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Molecular Weight 678.73
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Formula C44H30N4O4
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SMILES
OC1=CC=CC(/C2=C3C=CC(/C(C4=CC(O)=CC=C4)=C5C=C/C(N/5)=C(C(C=C/6)=NC6=C(C7=CC=C2N7)\C8=CC(O)=CC=C8)\C9=CC(O)=CC=C9)=N\3)=C1
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Synonyms
Tetra(3-hydroxyphenyl)porphyrin; 3-THPP
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
m-THPP Related Classifications
HY-W075248 Related Classifications
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