1. Anti-infection
  2. Fungal
    Bacterial

4-Chlorosalicylic acid 

Cat. No.: HY-W016867
Handling Instructions

4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibits monophenolase and diphenolase activity with IC50s of 1.89 mM and 1.10 mM. Potent antimicrobial activity. Against E. coli with the MIC of 250 μg/mL and with the MBC of 500 μg/mL.

For research use only. We do not sell to patients.

4-Chlorosalicylic acid Chemical Structure

4-Chlorosalicylic acid Chemical Structure

CAS No. : 5106-98-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

  • Biological Activity

  • Technical Information

  • References

Description

4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibits monophenolase and diphenolase activity with IC50s of 1.89 mM and 1.10 mM. Potent antimicrobial activity. Against E. coli with the MIC of 250 μg/mL and with the MBC of 500 μg/mL.

IC50 & Target

IC50: 1.89 mM (monophenolase), 1.10 mM (diphenolase)[1]

In Vitro

4-chlorosalicylic acid could inhibit both the diphenolase activity and the monophenolase activity of mushroom tyrosinase. 4-chlorosalicylic acid has broad-spectrum antimicrobial activity which could inhibits Gram-positive and Gram-negative bacteria and fungi[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.7951 mL 28.9754 mL 57.9509 mL
5 mM 1.1590 mL 5.7951 mL 11.5902 mL
10 mM 0.5795 mL 2.8975 mL 5.7951 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

172.56

Formula

C₇H₅ClO₃

CAS No.

5106-98-9

SMILES

C1=CC(=CC(=C1C(O)=O)O)Cl

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
4-Chlorosalicylic acid
Cat. No.:
HY-W016867
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4-Chlorosalicylic acid

Cat. No.: HY-W016867