2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-45588
    Geranylamine 6246-48-6 98%
    Geranylamine is an acyclic monoterpene amine that serves as a drug intermediate for the synthesis of a series of TRP channel modulators and antibacterial agents.
    Geranylamine
  • HY-47597
    Protein kinase G inhibitor-2 612829-80-8 98.0%
    Protein kinase G inhibitor-2 (Compound 266) is a mycobacterial protein kinase G inhibitor, with an IC50 of 3 μM. Protein kinase G inhibitor-2 can be used for mycobacterial infection research.
    Protein kinase G inhibitor-2
  • HY-48958
    Protein kinase G inhibitor-1 354544-70-0 98.0%
    Protein kinase G inhibitor-1 (Compound 270) is a mycobacterial protein kinase G inhibitor, with an IC50 of 0.9 μM. Protein kinase G inhibitor-1 can be used for mycobacterial infection research.
    Protein kinase G inhibitor-1
  • HY-49558
    7-Epiclindamycin 16684-06-3 98%
    7-Epiclindamycin is a common impurity in Clindamycin (HY-B1455) bulk agent. 7-epiclindamycin is produced during the synthesis of Clindamycin.
    7-Epiclindamycin
  • HY-50680
    HCVP-IN-1 877225-09-7 98%
    HCVP-IN-1 (compound 1) is a hepatitis C viral polymerase (HCVP) inhibitor.
    HCVP-IN-1
  • HY-50892
    (Rac)-Roscovitine 186692-44-4 98%
    (Rac)-Roscovitine ((Rac)-Seliciclib) is a selective cyclin-dependent kinases (CDKs) inhibitor. (Rac)-Roscovitine binds to the active sites of CDKs competitively with ATP, inhibiting the phosphorylation activity of CDKs. (Rac)-Roscovitine induces apoptosis in cancer cells. (Rac)-Roscovitine is promising for research of cancers or other diseases associated with CDK dysregulation, such as neurodegenerative diseases, cardiac disorders, viral and protozoan infections, glomerulonephritis, and chronic inflammation.
    (Rac)-Roscovitine
  • HY-A0035
    Faropenem 106560-14-9 98%
    Faropenem is a potent and orally active beta-lactam antibiotic. Faropenem demonstrates broad-spectrum in vitro antimicrobial activity against many gram-positive and -negative aerobes and anaerobes. Faropenem is resistant to hydrolysis by nearly all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Faropenem is developed as an oral proagent, faropenem medoxomil, for the research of respiratory tract infections.
    Faropenem
  • HY-A0112
    Cefcapene 135889-00-8 98%
    Cefcapene is an orally active cephem antibiotic. Cefcapene inactivates chromosome-encoded class C β-lactamases. Cefcapene can be used for antibacterial research.
    Cefcapene
  • HY-A0148
    Halofantrine 69756-53-2 98%
    Halofantrine (SKF-102886 hydrochloride; WR-171669 hydrochloride) is a blocker that delays the delayed rectifier potassium current by inhibiting human ERG channels, and it is a potent antimalarial agent with oral activity. Halofantrine inhibits the Cap1-dependent oxidative stress response of Candida albicans, suppresses ROS responses, and enhances the antifungal (Fungal) activity of oxidative damage agents. Halofantrine exhibits antifungal activity in the Galleria mellonella model, and shows antimalarial activity against Plasmodium strains both in vitro and in animal models. Halofantrine can be used in studies related to invasive candidiasis, falciparum malaria, and vivax malaria.
    Halofantrine
  • HY-A0161
    Chlophedianol 791-35-5 98%
    Chlophedianol (Clofedanol) is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs).
    Chlophedianol
  • HY-A0188
    Norzine dimalate 52239-63-1 98%
    Norzine dimalate (Thiethylperazine dimalate), a Phenothiazine (HY-Y0055) derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Norzine dimalate is also a selective ABCC1activator that reduces amyloid-β load in mice. Norzine dimalate has anti-emetic, antipsychotic and antimicrobial effects.
    Norzine dimalate
  • HY-B0013
    Lavofloxacin lactate 294662-18-3 98%
    Lavofloxacin lactate ((-)-ofloxacin lactate) is a class of broad-spectrum antimicrobials that can kill or inhibit a variety of bacteria. Lavofloxacin lactate binds to DNA rotase and topoisomerase IV, resulting in blocked DNA replication and repair, thus inhibiting bacterial growth. Lavofloxacin lactate can be used to study resistance mechanisms in bacteria, including studying resistance genes and mutations.
    Lavofloxacin lactate
  • HY-B0050
    Delmopinol 79874-76-3 98%
    Delmopinol is an antimicrobial agent that can be used in the oral cavity to inhibit the formation of dental biofilm.
    Delmopinol
  • HY-B0155
    Vicriviroc 306296-47-9 98%
    Vicriviroc (SCH 417690) is an orally active CCR5 antagonist with the IC50 of 10 nM, and also inhibts MIP-1α and intracellular calcium release induced by the ligand RANTES (10 nM) with the IC50 values of 0.91 nM and 16 nM,,respectively. Vicriviroc can inhibits human immunodeficiency virus type 1 (HIV-1) infection, and can also used for study of cancer.
    Vicriviroc
  • HY-B0691
    Ecabet 33159-27-2 98%
    Ecabet sodium (TA-2711) is currently applied to some clinical gastrointestinal disease by inhibiting the ROS production and improving Helicobacter pylori eradication. Ecabet sodium reduces apoptosis
    Ecabet
  • HY-B0699
    Cefpirome 84957-29-9 98%
    Cefpirome (HR 810) is a fourth generation cephalosporin. Cefpirome shows antibacterial activity. Cefpirome also has in vitro activity against Streptococcus pneumoniae.
    Cefpirome
  • HY-B0736
    Sertaconazole 99592-32-2 99.42%
    Sertaconazole (FI7056 free base) is a broad-spectrum topical antifungal agent, exhibits anti-inflammatory activity via activation of a p38-COX-2-PGE2 pathway. Sertaconazole is also a microtubule inhibitor, shows antiproliferative effect, induces apoptosis and autophagy, and can also inhibit the migration of cells.
    Sertaconazole
  • HY-B0756
    Cefazolin sodium pentahydrate 115850-11-8 98%
    Cefazolin sodium pentahydrate is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research. Cefazolin sodium pentahydrate has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD).
    Cefazolin sodium pentahydrate
  • HY-B1401
    Euquinine 83-75-0 98%
    Euquinine is an odorless salt that can be used as a substitute for quinine. Euquinine has anti-Plasmodium falciparum activity. Euquinine can be used for the study of multidrug resistance and bioavailability of Plasmodium falciparum .
    Euquinine
  • HY-B1568
    Bromodiphenhydramine 118-23-0 98%
    Bromodiphenhydramine (Ambodryl) is a potent antihistamine with antimicrobial property. Bromodiphenhydramine inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine can be used for cutaneous allergies research.
    Bromodiphenhydramine
Cat. No. Product Name / Synonyms Application Reactivity