2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1908R
    Midecamycin (Standard) 35457-80-8
    Lomefloxacin (Standard) is the analytical standard of Lomefloxacin. This product is intended for research and analytical applications. Lomefloxacin (SC47111A) is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc..
    Midecamycin (Standard)
  • HY-B1915R
    Micronomicin (Standard) 52093-21-7 98%
    Micronomicin (Standard) is the analytical standard of Micronomicin. This product is intended for research and analytical applications. Micronomicin (Gentamicin C2b) is an aminoglycoside antibiotic, with antibacterial and bactericidal activities.
    Micronomicin (Standard)
  • HY-B1916R
    Acetylspiramycin (Standard) 24916-51-6
    Acetylspiramycin (Standard) is the analytical standard of Acetylspiramycin. This product is intended for research and analytical applications. Acetylspiramycin (Spiramycin B) is an effective oral macrolide antibiotic produced by Streptomyces, It can inhibit the splenic lymphocyte transformation induced by phytohemagglutinin (PHA), LPS (HY-D1056) and antigen, reduce the procoagulant activity of macrophages, have good antibacterial effect on gram-positive bacteria, and is also an effective antigenic insect agent, which can be used to fight parasitic infection[1][2][3][4].
    Acetylspiramycin (Standard)
  • HY-B1920A
    Josamycin hydrochloride 11033-19-5 98%
    Josamycin (EN-141) hydrochloride is an orally active macrolide antibiotic exhibiting antimicrobial activity against a wide spectrum of pathogens, such as bacteria. The dissociation constant Kd from ribosome for Josamycin hydrochloride is 5.5 nM.
    Josamycin hydrochloride
  • HY-B1923A
    Piperacillin hydrate 66258-76-2 98%
    Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin hydrate is most commonly used in combination with the β-lactamase inhibitor Tazobactam (HY-B1418).
    Piperacillin hydrate
  • HY-B1975S
    Dithianon-d4 98%
    Dithianon-d4 is the deuterium labeled Dithianon (HY-B1975). Dithianon is a broad-spectrum anthraquinone fungicide with good adherence to the surface of leaves and fruits. Dithianon is used to control several several fungal of some fruits and vegetables, as anthracnose (Colletotrichum sp., Elsinoe ampelina), mildew (Plasmopara viticola), phomopsis (Phomopsis viticola), among others.
    Dithianon-d4
  • HY-B1978S
    Iprodione-d5 1215631-57-4 98%
    Iprodione-d5 is the deuterium labeled Iprodione. Iprodione, a dicarboximide fungicide, has a highly specific action, with a capacity to cause oxidative damage through production of free oxygen radicals (ROS). Iprodione does not appear to be species selective.
    Iprodione-d5
  • HY-B1984S
    p,p'-DDD-d8 93952-20-6 98%
    p,p'-DDD-d8 is the deuterium labeled p,p'-DDD[1]. p,p'-DDD (4,4’-DDD) is an organochlorine insecticide, a major metabolite of p,p'-DDT. p,p'-DDD is an agonist at estrogen receptor α(ERα) and ERβ. p,p'-DDD increases DNA damage, apoptosis and necrosis in peripheral blood. p,p'-DDD stimulates cell proliferation in SKBR3 cells. p,p'-DDD activates the AP-1 transcription factor. p,p'-DDD decreases sleep times of barbiturates and steroids in rats.
    p,p'-DDD-d8
  • HY-B2006S
    Fenvalerate-d5 1246815-00-8 98%
    Fenvalerate-d5 is the deuterium labeled Fenvalerate. Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC50 of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide.
    Fenvalerate-d5
  • HY-B2031S
    Pyriproxyfen-d6 2673269-99-1 98%
    Pyriproxyfen-d6 (S-31183-6) is the deuterium labeled Pyriproxyfen. Pyriproxyfen is a juvenile hormone analog and insect growth regulator. Pyriproxyfen is used in research related to dengue fever and malaria.
    Pyriproxyfen-d6
  • HY-B2041R
    Benfuracarb (Standard) 82560-54-1
    Benfuracarb (Standard) is the analytical standard of Benfuracarb. This product is intended for research and analytical applications. Benfuracarb is a broad-spectrum carbamate insecticide with crop protection activity. Benfuracarb is used to control springtails, aphids, and other pests, typically on sugar beet crops. Benfuracarb exhibits toxicity to humans and aquatic organisms. Benfuracarb exposure to zebrafish embryos resulted in a reduction in the body length of zebrafish larvae. Superoxide dismutase (SOD) activity was significantly increased after Benfuracarb treatment. Benfuracarb also interfered with the transcriptional levels of marker genes associated with early embryonic development.
    Benfuracarb (Standard)
  • HY-B2060R
    Tiamulin (Standard) 55297-95-5 98%
    Tiamulin (Standard) is the analytical standard of Tiamulin. This product is intended for research and analytical applications. Tiamulin (Thiamutilin) is a diterpenic antibiotic that is widely used in pigs and poultry for the control of infectious diseases. Tiamulin is effectively used in the study of airsacculitis, which is primarily caused by Mycoplasma spp.
    Tiamulin (Standard)
  • HY-B2144L
    Chitosan (≥95% deacetylated,mushroom) 9012-76-4 98%
    Chitosan (≥95% deacetylated,mushroom) is a polysaccharide obtained by deacetylating chitin from mushroom.
    Chitosan (≥95% deacetylated,mushroom)
  • HY-B2144M
    Chitosan (85%~90% deacetylated,mushroom) 9012-76-4 98%
    Chitosan (85%-90% deacetylated,mushroom) is a polysaccharide obtained by deacetylating chitin from mushroom.
    Chitosan (85%~90% deacetylated,mushroom)
  • HY-B2184S
    Sofalcone-d4 98%
    Sofalcone-d4 is deuterated labeled Sofalcone. Sofalcone, a gastric antiulcer agent, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium.
    Sofalcone-d4
  • HY-D0162R
    Malachite green hemioxalate (Standard) 2437-29-8
    Malachite green hemioxalate (Standard) is the analytical standard of Malachite green hemioxalate (HY-D0162). This product is intended for research and analytical applications. Malachite green hemioxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate has antimicrobial activity, which is attributed to inhibition of intracellular enzymes, intercalation into DNA, and/or interaction with cellular membranes. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo.
    Malachite green hemioxalate (Standard)
  • HY-D0226R
    Quinizarin (Standard) 81-64-1 98%
    Quinizarin (Standard) is the analytical standard of Quinizarin. This product is intended for research and analytical applications. Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth.
    Quinizarin (Standard)
  • HY-D0958R
    Methylene blue hydrate (Standard) 122965-43-9
    Methylene blue (hydrate) (Standard) is the analytical standard of Methylene blue (hydrate). This product is intended for research and analytical applications. Methylene blue (Basic Blue 9) hydrate is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue hydrate through the nitric oxide syntase/guanylate cyclase signalling pathway to reduce prepulse inhibition. Methylene blue hydrate is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue hydrate is a Tau aggregation inhibitor. Methylene blue hydrate reduces cerebral edema, attenuated microglial activation and reduced neuroinflammation.
    Methylene blue hydrate (Standard)
  • HY-DY1024
    TPE-MI (solution) 1245606-71-6
    TPE-MI (Tetraphenylethene maleimide) (solution) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .
    Solvent and concentration: DMSO: 10 mM
    TPE-MI (solution)
  • HY-DY1051
    Resazurin sodium (solution) 62758-13-8
    Resazurin sodium (Diazoresorcinol sodium) (solution) is a non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin sodium is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin sodium can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) .
    Solvent and Concentration: Sterile water: 10 mM
    Resazurin sodium (solution)
Cat. No. Product Name / Synonyms Application Reactivity