2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N14756
    6"'-Deamino-6"'-hydroxyneomycin B 78524-73-9 98%
    6"'-Deamino-6"'-hydroxyneomycin B is an aminoglycosyl antibiotic that can be produced by Streptomyces fradiae UC 75 and is active against both Gram-positive and Gram-negative bacteria. 6"'-Deamino-6"'-hydroxyneomycin B can be used as an intermediate in the biosynthesis of neomycin.
    6
  • HY-N14758
    6"'-Deamino-6"'-hydroxyparomomycin I 78524-72-8 98%
    6"'-Deamino-6"'-hydroxyparomomycin I is an amino glycosyl antibiotic that can be produced by Streptomyces rimosus forma paromomycinus A67 15. It is active against both Gram-positive and Gram-negative bacteria. 6"'-Deamino-6"'-hydroxyparomomycin I can be used as an intermediate in the biosynthesis of paromomycin.
    6
  • HY-N14763
    3'-O-Decarbamoylirumamycin 99486-52-9 98%
    3'-O-Decarbamoylirumamycin is a 20-membered macrolide antibiotic produced by Streptomyces subflavus subsp.Irumaensis . 3'-O-Decarbamoylirumamycin has certain inhibitory effect on plant pathogenic fungi such as Piricularia oryzae, and Sclerotinia cinerea.
    3'-O-Decarbamoylirumamycin
  • HY-N14776
    11-Demethyltomaymycin 55511-85-8 98%
    11-Demethyltomaymycin is an antibiotic. 11-Demethyltomaymycin has antiviral activity against Escherichia coli T1 and T3 phages and antibacterial activity against Gram-positive bacteria. In addition, 11-Demethyltomaymycin is cytotoxic to leukemia L1210 cells.
    11-Demethyltomaymycin
  • HY-N14781
    10-Decarbamoyloxy-9-dehydromitomycin B 74148-44-0 98%
    10-Decarbamoyloxy-9-dehydromitomycin B is a mitomycin. 10-Decarbamoyloxy-9-dehydromitomycin B has antibacterial and antitumor activity.
    10-Decarbamoyloxy-9-dehydromitomycin B
  • HY-N14847
    1-Hydroxyauramycin B 79206-72-7 98%
    1-Hydroxyauramycin B is an anthracycline antibiotic. 1-Hydroxyauramycin B has anti-Gram-positive bacteria and anti-tumor cell activity.
    1-Hydroxyauramycin B
  • HY-N14937
    Albaflavenone 157078-47-2 98%
    Albaflavenone is a sesquiterpene antibiotic with a zizaene skeleton. Albaflavenone is active against Bacillus subtilis.
    Albaflavenone
  • HY-N14958
    Dedesosaminyl-5-O-mycaminosyl-10,11-dihydromycinamicin IV 83883-27-6 98%
    Dedesosaminyl-5-O-mycaminosyl-10,11-dihydromycinamicin IV is an antibiotic, and its biological activity is similar to that of Tylosin (HY-B0519A).
    Dedesosaminyl-5-O-mycaminosyl-10,11-dihydromycinamicin IV
  • HY-N14959
    Deacetylravidomycin N-oxide 114494-30-3 98%
    Deacetylravidomycin N-oxide is an antibiotic that can be produced by Streptomyces ravidus S50905. Deacetylravidomycin N-oxide is active against Gram-positive bacteria but inactive against Gram-negative bacteria. Deacetylravidomycin N-oxide has antitumor activity against P388 leukemia and methamphetamine A fibrosarcoma.
    Deacetylravidomycin N-oxide
  • HY-N14972
    3,6-Dihydroxyindoxazene 86004-57-1 98%
    3,6-Dihydroxyindoxazene, an antibiotic can be isolated from C. violaceum, exhibits a selective activity against Gram-negative bacteria.
    3,6-Dihydroxyindoxazene
  • HY-N15075
    Espinomycin A2 40867-12-7 98%
    Espinomycin A2 is a sixteen-membered macrolide antibiotic. Espinomycin A2 is active against Gram-positive bacteria.
    Espinomycin A2
  • HY-N15097
    Dihydrocompactin 78366-44-6 98%
    Dihydrocompactin, an antifungal metabolite, is an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase (HMG-CoA reductase) from Penicillium citrinum.
    Dihydrocompactin
  • HY-N15141
    γ-Thujaplicin 672-76-4
    γ-Thujaplicin is a Hinokitiol (HY-B2230)-related compound that can be isolated from the wood of Thujopsis dolabrata. γ-Thujaplicin shows strong cytotoxic activities against human stomach cancer cell lines KATO-III and Ehrlich’s ascites carcinoma. γ-Thujaplicin exhibits potent and broad-spectrum antifungal activity on wood-rotting fungi, and insecticidal activity on the noxious insects. γ-Thujaplicin can be used for cancer and infection research and pest management.
    γ-Thujaplicin
  • HY-N15146
    Aralia-saponin I 289649-54-3 98%
    Aralia-saponin I is a saponin that can be isolated from Aralia elata, possessing high binding affinity for aerolysin and capable of binding to amino acids critical for aerolysin function. Aralia-saponin I can be utilized in research on infections caused by Aeromonas hydrophila.
    Aralia-saponin I
  • HY-N15159
    Cladophorol A 146776-30-9 98%
    Cladophorol A is a cyclic GMP-AMP synthase (cGAS) inhibitor. Cladophorol A binds to the conserved adenosine nucleobase binding site within the cGAS active site to inhibit its catalytic activity. Cladophorol A effectively inhibits the overactivation of the cGAS-STING pathway with an IC50 of 370 nM. Cladophorol A inhibits asexual blood-stage Plasmodium falciparum with an EC50 of 0.7 μg/mL. Cladophorol A can be used for the researches of inflammatory disease and malaria.
    Cladophorol A
  • HY-N15193
    Cystocholic acid 73386-01-3 98%
    Cystocholic acid is the metabolite of bile acid, and exhibits the antimicrobial potential.
    Cystocholic acid
  • HY-N15215
    Antiviral agent 64 1004319-60-1 98%
    Antiviral agent 64 (Compound 12) is a diarylheptanoid that can be isolated from Alpinia officinarum. Antiviral agent 64 exhibits cytotoxicity in human neuroblastoma cell IMR-32 with an IC50 of 0.23 μM. Antiviral agent 64 exhibits antiviral efficacy, that inhibits RSV, poliovirus, measles virus, HSV-1, and influenza virus H1N1, with EC50 of 13.3, 3.7, 6.3, 5.7, and <10 μg/mL, respectively.
    Antiviral agent 64
  • HY-N15217
    Antiviral agent 65 1004319-61-2 98%
    Antiviral agent 65 (compound 9) is an antiviral agent that targets influenza H1N1 virus (EC50=7 μg/mL).
    Antiviral agent 65
  • HY-N15249
    4"-Isovalerylspiramycin I 267662-22-6 98%
    4"-Isovalerylspiramycin I (Isovalerylspiramycin I) is a topoisomerase 1 (TOP1) inhibitor and an antitumor agent. 4"-Isovalerylspiramycin I directly binds to TOP1, suppresses DNA replication, and induces DNA damage. 4"-Isovalerylspiramycin I downregulates phosphorylated CHEK1 and the ATR/CHEK1 DNA damage repair pathway, blocks DNA repair, and augments DNA damage. 4"-Isovalerylspiramycin I suppresses proliferation, migration, and invasion of osteosarcoma cells. 4"-Isovalerylspiramycin I induces apoptosis and cell cycle arrest in osteosarcoma cells. 4"-Isovalerylspiramycin I exerts antibacterial activity against methicillin-resistant Staphylococcus aureus. 4"-Isovalerylspiramycin I can be used for the research of osteosarcoma, upper respiratory bacterial infections, and methicillin-resistant Staphylococcus aureus infection.
    4
  • HY-N15250
    4"-Isovalerylspiramycin III 212125-76-3
    4"-Isovalerylspiramycin III (Shengjimycin A1) is an antibiotic. 4"-Isovalerylspiramycin III is the main active component among the multiple components of the antibiotic Shengjimycin.
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Cat. No. Product Name / Synonyms Application Reactivity