γ-Thujaplicin
γ-Thujaplicin is a Hinokitiol (HY-B2230)-related compound that can be isolated from the wood of Thujopsis dolabrata. γ-Thujaplicin shows strong cytotoxic activities against human stomach cancer cell lines KATO-III and Ehrlich’s ascites carcinoma. γ-Thujaplicin exhibits potent and broad-spectrum antifungal activity on wood-rotting fungi, and insecticidal activity on the noxious insects. γ-Thujaplicin can be used for cancer and infection research and pest management.
For research use only. We do not sell to patients.
- CAS No.: 672-76-4
- Formula: C10H12O2
- Molecular Weight:164.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| G-361 | IC50 |
1.15 μM
Compound: gamma-Thujaplicin
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Competitive inhibition of tyrosinase in human G-361 cells incubated for 10 mins measured for 2 hrs by MBTH-based spectrophotometry
Competitive inhibition of tyrosinase in human G-361 cells incubated for 10 mins measured for 2 hrs by MBTH-based spectrophotometry
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[PMID: 25288494] |
Chemical Information
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CAS No. 672-76-4
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Molecular Weight 164.20
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Formula C10H12O2
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SMILES
O=C1C=CC(C(C)C)=CC=C1O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Matsumura E, et al. Cytotoxicity of the hinokitiol-related compounds, gamma-thujaplicin and beta-dolabrin. Biol Pharm Bull. 2001 Mar;24(3):299-302. [Content Brief]
[2]. Inamori Y, et al. Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities. Biol Pharm Bull. 2000 Aug;23(8):995-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
γ-Thujaplicin Related Classifications
HY-N15141 Related Classifications
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