2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P2661A
    FA-Leu-Gly-Pro-Ala-OH TFA 98%
    FA-Leu-Gly-Pro-Ala-OH TFA is a furylacryloyl-terminal tetrapeptide that serves as a substrate for bacterial collagenase and spirochete metalloendopeptidase. FA-Leu-Gly-Pro-Ala-OH TFA is specifically hydrolyzed by spirochete collagenase only at the Leu-Gly bond. FA-Leu-Gly-Pro-Ala-OH TFA can be used to determine the equilibrium constant of peptide bond hydrolysis, and also to detect collagenase-mediated cleavage reactions via turbidimetry based on absorbance reduction.
    FA-Leu-Gly-Pro-Ala-OH TFA
  • HY-P2818B
    Alkaline phosphatase, Chicken Intestine 9001-78-9
    Alkaline Phosphatase (Apase), Chicken Intestine is an alkaline phosphatase from Chicken Intestine, and is one of the most active alkaline phosphatases. Alkaline phosphatase, Chicken Intestine is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase, Chicken Intestine reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase, Chicken Intestine improves survival rate of mice infected with E. coli. Alkaline phosphatase, Chicken Intestine improves TNBS-induced colon inflammation.
    Alkaline phosphatase, Chicken Intestine
  • HY-P2818F
    Alkaline phosphatase, Human (HEK293) 9001-78-9 98%
    Alkaline phosphatase (Apase), Human (HEK293) is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase improves survival rate of mice infected with E. coli. Alkaline phosphatase improves TNBS-induced colon inflammation.
    Alkaline phosphatase, Human (HEK293)
  • HY-P2848A
    Cholesterol oxidase, rhodococcus sp 9028-76-6 98%
    Cholesterol oxidase, Rhodococcus sp. is a key enzyme in the cholesterol degradation process. It catalyzes the isomerization and oxidation of cholesterol mediated by the coenzyme FAD. Research indicates that cholesterol oxidase plays a crucial role in the pathogenicity of Mycobacterium tuberculosis by modulating the host macrophage immune response through inhibition of the Toll-like receptor 2 (TLR2) signaling pathway, thereby enhancing the survival of Mycobacterium tuberculosis. Cholesterol oxidase, from Rhodococcus sp., shows potential for research in the field of tuberculosis.
    Cholesterol oxidase, rhodococcus sp
  • HY-P2915A
    Protocatechuate 3,4-Dioxygenase, Bacteria 98%
    Protocatechuate 3,4-Dioxygenase, Bacteria is a dioxygenase. Protocatechuate 3,4-Dioxygenase, Bacteria belongs to the non-heme iron dioxygenase class. Protocatechuate 3,4-Dioxygenase, Bacteria catalyzes the cleavage of the aromatic ring of 3,4-dihydroxybenzoate, attaching two atoms of molecular oxygen to the compound to generate β-carboxy-cis,cis-muconate. Protocatechuate 3,4-Dioxygenase, Bacteria is a key enzyme in the β-ketoadipic acid pathway. Protocatechuate 3,4-Dioxygenase, Bacteria is found in marine bacteria associated with Roseobacter. Protocatechuate 3,4-Dioxygenase, Bacteria can be isolated from Pseudomonas aeruginosa.
    Protocatechuate 3,4-Dioxygenase, Bacteria
  • HY-P2973A
    Aspergillopepsin I (Xeno-free) 98%
    Aspergillopepsin I (Xeno-free) is an acid protease and aspartic protease. Aspergillopepsin I (Xeno-free) is derived from the marine fungus Aspergillus tubingensis. Aspergillopepsin I from Aspergillus tubingensis hydrolyzes glycinin, especially the 7S globulin.
    Aspergillopepsin I (Xeno-free)
  • HY-P2988H
    Neuraminidase,Vibrio cholerae
    Neuraminidase,Vibrio cholerae (EC 3.2.1.18) is a glycoside hydrolase enzyme that cleave the glycosidic linkages of neuraminic acids.
    Neuraminidase,Vibrio cholerae
  • HY-P2998A
    β-Lactamase, Pseudomonas aeruginosa
    β-Lactamase, Pseudomonas aeruginosa (EC 3.5.2.6) inactivates β-lactam antibiotics by breaking open the β-lactam ring.
    β-Lactamase, Pseudomonas aeruginosa
  • HY-P2998B
    β-Lactamase Blend
    β-Lactamase Blend (EC 3.5.2.6) inactivates β-lactam antibiotics by breaking open the β-lactam ring.
    β-Lactamase Blend
  • HY-P3051A
    CKS-17 (dimer) 162873-95-2 98%
    CKS-17 (dimer) is the dimer of CKS-17 (HY-P3051). CKS-17 (dimer) can be prepared by introducing a naturally occurring cysteine at the carboxyl terminus and dimerizing via a cysteine-disulfide bond. CKS-17 is a synthetic retroviral envelope peptide. CKS-17 has a highly conserved amino acid sequence present in the transmembrane envelope proteins of numerous animal and human retroviruses. As an immunomodulatory epitope, CKS-17 exhibits inhibitory properties on a variety of immune functions.
    CKS-17 (dimer)
  • HY-P3425A
    AGPV TFA 98%
    AGPV TFA, a tetrapeptide, has the potential for prevention of schistosome parasite infection research.
    AGPV TFA
  • HY-P3823A
    Asp-Asp-Asp-Asp-Asp-Asp TFA 98%
    Asp-Asp-Asp-Asp-Asp-Asp TFA is a polyaspartic acid. The specificity of the catalytic and antigenic sites of influenza virus neuraminidase is related to the number of specific amino acids.
    Asp-Asp-Asp-Asp-Asp-Asp TFA
  • HY-P4027A
    HCV-1 e2 Protein (554-569) TFA 98%
    HCV-1 e2 Protein (554-569) TFA is one of the main antigenic regions of HCV envelope 2 (e2) protein. The HCV-1 e2 Protein (554-569) TFA contains a putative N-glycosylation site, which was previously thought to influence the immune recognition of e2.
    HCV-1 e2 Protein (554-569) TFA
  • HY-P4777A
    Dabcyl-RGVVNASSRLA-Edans TFA 98%
    Dabcyl-RGVVNASSRLA-Edans (Dabcyl-CMV-Edans) is a fluorogenic substrate for human cytomegalovirus (HCMV) protease.
    Dabcyl-RGVVNASSRLA-Edans TFA
  • HY-P5345A
    KLA peptide acetate 99.81%
    KLA peptide acetate is a naturally occurring Antibiotic peptide that is nontoxic outside of cells but is toxic when it enters into the interior of targeted cells. KLA peptide acetate can induce cell Apoptosis by disrupting mitochondrial membranes and activating Caspase. MG1-KLA acetate, formed by the coupling of KLA peptide acetate with MG1, can selectively induce apoptosis in pro-inflammatory microglia. KLA peptide acetate can be used for the research of liver fibrosis. KLA peptide acetate can be used for the research of neonatal hypoxic-ischemic encephalopathy.
    KLA peptide acetate
  • HY-P5829A
    CRAMP (140-173) (mouse) TFA 98%
    CRAMP (140-173) (mouse) TFA is a ortholog of human LL-37 antimicrobial peptide. CRAMP (140-173) (mouse) TFA inhibits LPS (HY-D1056)-induced responses, and can not colocalized with TLR3 in BEAS-2B cells.
    CRAMP (140-173) (mouse) TFA
  • HY-P5924A
    D-K6L9 426264-61-1 98%
    D-K6L9 shows antimicrobial and antibiofilm activities against P. aeruginosa from cystic fibrosis patients. D-K6L9 is stable and resistant to degradation by cystic fibrosis sputum proteases and will not induce bacterial resistance .
    D-K6L9
  • HY-P99438
    Anivovetmab 2370896-63-0 99.70%
    Anivovetmab (KIND-030) is an anti-VP2 protein (canine parvovirus major capsid protein) monoclonal antibody (IgG2 isotype). Anivovetmab has the potential for studying canine parvovirus infection.
    Anivovetmab
  • HY-P99532
    Urtoxazumab 502496-16-4
    Urtoxazumab (TMA-15) is a humanizedized monoclonal antibody against Shiga toxin (Stx) 2.
    Urtoxazumab
  • HY-P99753
    Nerelimomab 162774-06-3
    Nerelimomab (BAYX1351) is an anti-TNF-α antibody. Nerelimomab can be used for research of sepsis.
    Nerelimomab
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