Cholesterol oxidase, rhodococcus sp
Based on 2 publication(s) in Google Scholar
Cholesterol oxidase, Rhodococcus sp. is a key enzyme in the cholesterol degradation process. It catalyzes the isomerization and oxidation of cholesterol mediated by the coenzyme FAD. Research indicates that cholesterol oxidase plays a crucial role in the pathogenicity of Mycobacterium tuberculosis by modulating the host macrophage immune response through inhibition of the Toll-like receptor 2 (TLR2) signaling pathway, thereby enhancing the survival of Mycobacterium tuberculosis. Cholesterol oxidase, from Rhodococcus sp., shows potential for research in the field of tuberculosis.
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- CAS No.: 9028-76-6
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Publications Citing Use of MedChemExpress (MCE) Cholesterol oxidase, rhodococcus sp
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Biological Activity
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TLR2 |
Chemical Information
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CAS No. 9028-76-6
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SMILES
[Cholesterol oxidase, rhodococcus sp]
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Mater Today Bio
"Top-down and Bottom-up" cholesterol-depleting biomimetic nanoparticle for enhancing sonodynamic therapy against hepatocellular carcinoma. [Abstract]2025 Sep 30:35:102370. PMID: 41104047 -
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References
[1]. Cui H, et al. Heterologous Expression and Function of Cholesterol Oxidase: A Review. Protein Pept Lett. 2023;30(7):531-540. [Content Brief]
[2]. Brzostek A, et al. Cholesterol oxidase is required for virulence of Mycobacterium tuberculosis. FEMS Microbiol Lett. 2007 Oct;275(1):106-12. [Content Brief]
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