Cholesterol oxidase, Microorganism
Based on 2 publication(s) in Google Scholar
Cholesterol oxidase, Microorganism (ChOx, Microorganism) (EC 1.1.3.6) is a cholesterol oxidase identified from bacterial sources. Cholesterol oxidase, Microorganism catalyzes the oxidation of cholesterol to 4-cholesten-3-one, while simultaneously reducing oxygen to hydrogen peroxide. Cholesterol oxidase, Microorganism retains its enzymatic activity and exhibits improved catalytic efficiency upon immobilization. Cholesterol oxidase, Microorganism is applicable for cholesterol detection, steroid biotransformation, and research on tuberculosis-related diseases.
For research use only. We do not sell to patients.
- CAS No.: 9028-76-6
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Cholesterol oxidase, Microorganism
More
Biological Activity
Description
In Vitro
Cholesterol oxidase, Microorganism (5 days) degrades 84% and 50% of cholesterol respectively under optimized conditions, and can serve as a microbial source of cholesterol oxidase[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
EC Number
1.1.3.6
Enzyme Activity
＞20 U/mg solid
Specific Activity
≥80 U/mg protein
Unit Definition
One unit is defined as the amount of enzyme that will oxidate 1 μmol of cholesterol per min at pH 7.0 at 37°C.
Chemical Information
-
CAS No. 9028-76-6
-
Appearance Solid
-
Color Light yellow to yellow
-
SMILES
[Cholesterol oxidase, Microorganism]
-
Synonyms
ChOx, Microorganism
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
-
Journal Impact Factor
-
Most Recent
-
Mater Today Bio
"Top-down and Bottom-up" cholesterol-depleting biomimetic nanoparticle for enhancing sonodynamic therapy against hepatocellular carcinoma. [Abstract]2025 Sep 30:35:102370. PMID: 41104047 -
Solvent & Solubility
In Vitro:
H2O : ≥ 25 mg/mL
* "≥" means soluble, but saturation unknown.
Purity & Documentation
-
Data Sheet (274 KB)
-
SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
-
Handling Instructions (2659 KB)
References
[1]. Cui H, et al. Heterologous Expression and Function of Cholesterol Oxidase: A Review. Protein Pept Lett. 2023;30(7):531-540. [Content Brief]
[2]. Brzostek A, et al. Cholesterol oxidase is required for virulence of Mycobacterium tuberculosis. FEMS microbiology letters. 2007 Oct;275(1):106-12. [Content Brief]
[5]. Ghosh S, et al. Cholesterol-oxidase-magnetic nanobioconjugates for the production of 4-cholesten-3-one and 4-cholesten-3, 7-dione. Bioresource technology. 2018 Apr;254:91-96. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cholesterol oxidase, Microorganism Related Classifications
HY-P2848 Related Classifications
Powered by Bioz
Keywords
- Cholesterol oxidase, Microorganism
- 9028-76-6
- ChOx, Microorganism
- Xanthine Oxidase
- silane-modified iron(II
- III)oxide magnetic nanoparticles
- tuberculosis
- flavin adenine dinucleotide
- 4-cholesten-3-one
- Rhodococcus sp.
- hydrogen peroxide
- cholesterol
- 4-cholesten-3,7-dione
- Cholesterol oxidase
- 7-ketocholesterol
- Inhibitor
- inhibitor
- inhibit