2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W741555
    Dechlorogriseofulvin 3680-32-8 98%
    Dechlorogriseofulvin (7-Dechlorogriseofulvin) is an antibiotic, and exhibits inhibitory activity against various plant pathogenic fungi. Dechlorogriseofulvin inhibits Botrytis cinerea, Rhizoctonia solani, Pythium ultimum, and Sclerotinia sclerotiorum with MIC of 40.0 µg/ml, 43.9 µg/ml, 81.7 µg/ml, and 28.5 µg/ml, respectively.
    Dechlorogriseofulvin
  • HY-W741556
    Dehydrogriseofulvin 3573-90-8 98%
    Dehydrogriseofulvin can be isolated from Penicillium sp. Dehydrogriseofulvin inhibits Colletotrichum musae with MIC > 1 µg/scrip.
    Dehydrogriseofulvin
  • HY-W741557
    Griseofulvic Acid 469-54-5 98%
    Griseofulvic acid is a metabolite of the antifungal Griseofulvin (HY-17583). It induces protein aggregation and tubulin polymerization in cell-free assays.
    Griseofulvic Acid
  • HY-W742094
    Cycotiamine 6092-18-8 98%
    Cycotiamine is an S-acylated thiamine derivative with antiplasmodial activity. Cycotiamine inhibits the proliferation of Plasmodium falciparum and Plasmodium knowlesi. Cycotiamine can be used in malaria-related research.
    Cycotiamine
  • HY-W742100
    Scillarenin 465-22-5 98%
    Scillarenin is a plant bufadienolide and cardiotonic agent. Scillarenin selectively inhibits replication of picornaviruses, in particular, rhinovirus.
    Scillarenin
  • HY-W743773
    γ-Cyhalothrin 76703-62-3 98%
    γ-Cyhalothrin is an orally active, blood-brain barrier permeable Type II synthetic pyrethroid insecticide. γ-Cyhalothrin is the insecticidally active enantiomer of λ-Cyhalothrin (HY-B0836). γ-Cyhalothrin disrupts voltage-gated sodium channels, induces salivation and reduces spontaneous activity in rats. γ-Cyhalothrin exerts toxic effects on aquatic invertebrates and fish, triggers community-level effects in aquatic ecosystems, and inhibits host-seeking Ixodes scapularis nymphs in residential lawn ecotones. γ-Cyhalothrin is applicable to insecticidal-related research.
    γ-Cyhalothrin
  • HY-W744633
    Cefdaloxime 80195-36-4 98%
    Cefdaloxime is an orally active cephalosporin and HR-916 ester metabolite. Cefdaloxime has a broad spectrum of activity against pathogens such as the majority of members of the family Enterobacteriaceae, staphylococci, Streptococcus spp., Neisseria gonorrhoeae, Moraxella catarrhalis, Haemophilus influenzae.
    Cefdaloxime
  • HY-W747311
    Ritipenem 84845-57-8 98%
    Ritipenem is a penicillin antibiotic, that targets penicillin-binding protein with good affinity (IC50 in levels of ng/mL), and exhibits antibacterial properties. Ritipenem exhibits antiviral activity against Haemophilus influenzae.
    Ritipenem
  • HY-W747504
    TAN-420E 91700-93-5 98%
    TAN-420E (Dihydroherbimycin A) is an antibiotic, that can be isolated from the fermentation product of Streptomyces hygroscopicus. TAN-420E exhibits cytotoxicity in cancer cells P-388 and KB. TAN-420E scavenges DPPH free radicals with an IC50 of 1.3 μM.
    TAN-420E
  • HY-W747507
    Reveromycin D 144860-70-8 98%
    Reveromycin D is a bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells and has pH-dependent antifungal activity against C. albicans (MICs=2 and >500 μg/mL at pH 3 and 7.4, respectively).2 Reveromycin D also inhibits proliferation of KB and K562 cells (IC50s=1.6 and 1.3 μg/mL, respectively).
    Reveromycin D
  • HY-W747516
    Butylcycloheptylprodigiosin 352304-41-7 98%
    Butylcycloheptylprodigiosin is the secondary metabolite produced by some bacteria, such as Streptomyces. Butylcycloheptylprodigiosin is a red-pigmented antibiotic and exhibits cytotoxicity against cancer cell MCF-7 and HDF.
    Butylcycloheptylprodigiosin
  • HY-W747601
    Chlorphoxim 14816-20-7 98%
    Chlorphoxim is a broad-spectrum and highly efficient insecticide. Chlorphoxim kills pests by inhibiting AChE. Chlorphoxim inhibits the activities of SOD and CAT in zebrafish embryos. Chlorphoxim induces oxidative stress in zebrafish embryos by activating ROS. Chlorphoxim induces apoptosis by upregulating the expression levels of Bax, Bcl2 and p53 in zebrafish embryos. Chlorphoxim exhibits neurotoxicity and developmental toxicity. Chlorphoxim is used in agricultural research for the control of various pests.
    Chlorphoxim
  • HY-W747609
    Butoxycarboxim 34681-23-7 98%
    Butoxycarboxim is an organophosphate insecticide/acaricide mainly used in agriculture to control a variety of pests.
    Butoxycarboxim
  • HY-W747994
    Atramycin A 137109-48-9 98%
    Atramycin A is an isotetracenone type antitumor antibiotic.
    Atramycin A
  • HY-W748000
    Kocurin 1374772-61-8 98%
    Kocurin (PM181104) is a thiazolyl cyclic-peptide antibiotic. Kocurin inhibits bacterial growth by impeding bacterial protein biosynthesis during the translation phase. Kocurin has strong inhibitory activity against Gram-positive bacteria, but no activity against fungi and Gram-negative bacteria.
    Kocurin
  • HY-W748786
    Fenpyrazamine 473798-59-3 98%
    Fenpyrazamine is an antifungal agent. Fenpyrazamine possesses antifungal, preventative, systemic, and lesion-inhibiting activities, as well as a long-lasting effect. Fenpyrazamine targets 3-keto reductase in the ergosterol biosynthesis pathway. Fenpyrazamine is effective against gray mold, stem rot, and brown rot.
    Fenpyrazamine
  • HY-W749146
    Raja 42 1198782-86-3 98%
    Raja 42 is a gamma lactam antibiotic. Raja 42 is effective against a variety of different bacterias, including Gram-positive and Gram-negative bacteria, such as C. difficile strains.
    Raja 42
  • HY-W749636
    N-De-2,4-difluorobenzyl dolutegravir 1485081-26-2 98%
    N-De-2,4-difluorobenzyl dolutegravir is a metabolite of Dolutegravir (HY-13238). Dolutegravir is a HIV integrase inhibitor inhibitor.
    N-De-2,4-difluorobenzyl dolutegravir
  • HY-W749691
    (S)-Velpatasvir-13c,d3 98%
    (S)-Velpatasvir-13C,d3 ((S)-GS-5816-13C,d3) is 13C labeled Velpatasvir. Velpatasvir (VEL, GS-5816) is a novel pan-genotypic hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor with activity against genotype 1 (GT1) to GT6 HCV replicons. Velpatasvir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 2.16 μM.
    (S)-Velpatasvir-13c,d3
  • HY-W750902
    Oxymatrine-d3 2714484-46-3 98%
    Oxymatrine-d3 is the deuterium labeled Oxymatrine (HY-N0158). Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral infection.
    Oxymatrine-d3
Cat. No. Product Name / Synonyms Application Reactivity