Dechlorogriseofulvin
Dechlorogriseofulvin (7-Dechlorogriseofulvin) is an antibiotic, and exhibits inhibitory activity against various plant pathogenic fungi. Dechlorogriseofulvin inhibits Botrytis cinerea, Rhizoctonia solani, Pythium ultimum, and Sclerotinia sclerotiorum with MIC of 40.0 µg/ml, 43.9 µg/ml, 81.7 µg/ml, and 28.5 µg/ml, respectively.
For research use only. We do not sell to patients.
- CAS No.: 3680-32-8
- Formula: C17H18O6
- Molecular Weight:318.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
>10 μM
Compound: 9
|
Cytotoxicity against human A2780 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against human A2780 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 31359750] |
| HT-29 | IC50 |
>20 μM
Compound: 13
|
Cytotoxicity against human HT-29 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human HT-29 cells after 3 days by sulforhodamine B assay
|
[PMID: 28409637] |
| L5178Y | IC50 |
>10 μM
Compound: 9
|
Cytotoxicity against mouse L5178Y cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against mouse L5178Y cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 31359750] |
| MCF7 | IC50 |
>20 μM
Compound: 13
|
Cytotoxicity against human MCF7 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human MCF7 cells after 3 days by sulforhodamine B assay
|
[PMID: 28409637] |
Chemical Information
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CAS No. 3680-32-8
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Molecular Weight 318.32
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Formula C17H18O6
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SMILES
C[C@@H]1CC(C=C(OC)[C@]12C(C3=C(OC)C=C(OC)C=C3O2)=O)=O
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Synonyms
7-Dechlorogriseofulvin
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)