Raja 42
Raja 42 is a gamma lactam antibiotic. Raja 42 is effective against a variety of different bacterias, including Gram-positive and Gram-negative bacteria, such as C. difficile strains.
For research use only. We do not sell to patients.
- CAS No.: 1198782-86-3
- Formula: C14H15ClN2O2
- Molecular Weight:278.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| 184B5 | GI50 |
93.72 μM
Compound: 2i
|
Cytotoxicity against human 184B5 cells after 48 hrs by SRB assay
Cytotoxicity against human 184B5 cells after 48 hrs by SRB assay
|
[PMID: 19804979] |
| MCF-10A | GI50 |
70.67 μM
Compound: 2i
|
Cytotoxicity against human MCF10A cells after 48 hrs by SRB assay
Cytotoxicity against human MCF10A cells after 48 hrs by SRB assay
|
[PMID: 19804979] |
| MCF7 | GI50 |
51.24 μM
Compound: 2i
|
Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
|
[PMID: 19804979] |
| MDA-MB-231 | GI50 |
26.48 μM
Compound: 2i
|
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by SRB assay
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by SRB assay
|
[PMID: 19804979] |
| MDA-MB-468 | GI50 |
82.84 μM
Compound: 2i
|
Cytotoxicity against human MDA-MB-468 cells after 48 hrs by SRB assay
Cytotoxicity against human MDA-MB-468 cells after 48 hrs by SRB assay
|
[PMID: 19804979] |
Chemical Information
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CAS No. 1198782-86-3
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Molecular Weight 278.73
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Formula C14H15ClN2O2
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SMILES
O=C1N(C2=C(C1=O)C(Cl)=CC=C2)CN3CCCCC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)