2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

PDF 93.1 MB

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P990646
    Anti-TPBG Antibody (PF-06263507) 98.68%
    The Anti-TPBG Antibody (PF-06263507) is a humanized antibody expressed in CHO cells that targets TPBG. PF-06263507 has a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 145.8 kDa. The isotype control for PF-06263507 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-TPBG Antibody (PF-06263507)
  • HY-P990760
    Rezorstobart 2762201-86-3
    Rezorstobart is an anti-KLRB1 human IgG1 κ monoclonal antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
    Rezorstobart
  • HY-P990770
    Ucenprubart 2414559-57-0 98.66%
    Ucenprubart is an anti-CD200R1 human IgG4κ monoclonal antibody. Recommend Isotype Controls: Human IgG4 kappa, Isotype Control (HY-P99003).
    Ucenprubart
  • HY-P990838
    Anti-IL-12 p70 Antibody (20C2)
    Anti-IL-12 p70 Antibody (20C2) is an anti-human IL-12 p70 IgG1 monoclonal antibody. Anti-IL-12 p70 Antibody (20C2) can inhibit the production of IFN-γ. Anti-IL-12 p70 Antibody (20C2) can be used for research on inflammation conditions. The recommend isotype control of Anti-IL-12 p70 Antibody (20C2): Rat IgG1 kappa, Isotype Control (HY-P99979).
    Anti-IL-12 p70 Antibody (20C2)
  • HY-W009338
    H-Val-Tyr-OH 3061-91-4 99.11%
    H-Val-Tyr-OH (Val-Tyr) is a dipeptide formed by the connection of valine and tyrosine via a peptide bond. H-Val-Tyr-OH is a potential IKKα inhibitor and can be used in the research of cancer and inflammatory diseases.
    H-Val-Tyr-OH
  • HY-W010841
    Levocetirizine dihydrochloride 130018-87-0 99.8%
    Levocetirizine dihydrochloride ((R)-Cetirizine dihydrochloride) is a third-generation peripheral H1-receptor antagonist. Levocetirizine dihydrochloride is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine dihydrochloride has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria.
    Levocetirizine dihydrochloride
  • HY-W011168
    8-Bromo-2'-deoxyguanosine 13389-03-2 ≥98.0%
    8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and an early biomarker of inflammation-induced oxidative tissue damage. The formation of 8-Bromo-2'-deoxyguanosine precedes that of oxidative and nitrative products, and it can be generated via the MPO-H2O2-Cl--Br- system. 8-Bromo-2'-deoxyguanosine serves as the immunogen for preparing the monoclonal antibody mAb8B3, which can be used to detect early DNA modifications in preclinical models; its urinary level also increases significantly in inflammatory disease models. 8-Bromo-2'-deoxyguanosine can also be produced in the dermis of UV-B irradiated mice, and the extract of Coprinus comatus significantly reduces its level. 8-Bromo-2'-deoxyguanosine finds applications in studies related to inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation.
    8-Bromo-2'-deoxyguanosine
  • HY-W013164
    SC-58125 162054-19-5 99.92%
    SC-58125 is a potent and selective inhibitor of cyclooxygenase 2 (COX-2), with an IC50 of 0.04 μM. SC-58125 exhibits antitumor activity in vitro and in vivo. SC-58125 also can inhibit edema at the inflammatory site and has analgesic effect.
    SC-58125
  • HY-W113433
    3-Hydroxybenzeneethanol 13398-94-2 99.25%
    3-Hydroxybenzeneethanol is a phenethyl alcohol antioxidant. 3-Hydroxybenzeneethanol can inhibit ROS production induced by cumene hydroperoxide. 3-Hydroxybenzeneethanol can be used for the research of inflammation.
    3-Hydroxybenzeneethanol
  • HY-W355779
    Gliadins 9007-90-3
    Gliadins (Tyrosylprolylglutaminylprolylglutamine) comprise a family of glutamine- and proline-rich monomeric proteins that plays an role in autoimmune disease, such as celiac disease.
    Gliadins
  • HY-W701069
    Isomyosmine 53844-46-5
    Isomyosmine is a nitrate reductase inhibitor. Isomyosmine is a nicotine related alkaloid present in solanecea plants containing nicotine. Isomyosmine can be used for research of inflammation and age-related disorders
    Isomyosmine
  • HY-W782032
    3D-Monophosphoryl Lipid A-5 1699735-79-9 99.60%
    3D-Monophosphoryl Lipid A-5 (3D-MPLA-5) is a TLR agonist that serves as a vaccine adjuvant and enhances the immunogenicity of vaccines.
    3D-Monophosphoryl Lipid A-5
  • HY-Y0320GL
    Dimethyl sulfoxide (GMP Like) 67-68-5 99.99%
    Dimethyl sulfoxide (DMSO) (GMP Like) is the GMP Like class Dimethyl sulfoxide (HY-Y0320C). Dimethyl sulfoxide is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity.
    Dimethyl sulfoxide (GMP Like)
  • HY-113037CS
    Farnesyl pyrophosphate-d2 triammonium
    Farnesyl pyrophosphate-d2 (Farnesyl diphosphate-d2) triammonium is a deuterium labeled Farnesyl pyrophosphate triammonium (HY-113037C). Farnesyl pyrophosphate ammonium is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate ammonium is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate ammonium is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases.
    Farnesyl pyrophosphate-d2 triammonium
  • HY-W015240S
    N-Acetyl-L-glutamic acid-d5 99.71%
    N-Acetyl-L-glutamic acid-d5 is the deuterium labeled N-Acetyl-L-glutamic acid (HY-W015240). N-Acetyl-L-glutamic acid is a type of glutamic acid that can serve as a component of cell culture media. When combined with media containing inorganic salts, carbohydrates, vitamins, and amino acids, N-Acetyl-L-glutamic acid plays roles in promoting cell growth, enhancing antibody production, etc. N-Acetyl-L-glutamic acid is also an endogenous metabolite that can be found in the brain. Additionally, as an IgE blocker, N-Acetyl-L-glutamic acid can be used in the research of allergic diseases.
    N-Acetyl-L-glutamic acid-d5
  • HY-W018772S12
    D-Ribose-d6 ≥99.0%
    D-Ribose-d6 is the deuterium labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein gl
    D-Ribose-d6
  • HY-11087
    SD 0006 271576-80-8 98.22%
    SD 0006 (SD-06) is an orally active, selective, ATP-competitive and potent diaryl pyrazole inhibitor of p38α MAP kinase, with an IC50 of 110 nM for p38α.
    SD 0006
  • HY-12235
    PI-3065 955977-50-1 98.97%
    PI-3065 is a potent inhibitor of PI3K p110δ, with IC50 and Ki values of 5 nM and 1.5 nM, and exhibits less potent activity against p110α, p110β, p110γ with IC50s of 910, 600, >10000 nM.
    PI-3065
  • HY-B0482
    Acemetacin 53164-05-9 99.95%
    Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.
    Acemetacin
  • HY-B1063
    Terpin hydrate 2451-01-6 98.0%
    Terpin hydrate (cis-Terpin hydrate) is an expectorant, commonly used in the research of mucus associated with acute and chronic bronchitis. Terpin hydrate ameliorates Paraquat dichloride (HY-B0864A)-induced lung damage.
    Terpin hydrate
Cat. No. Product Name / Synonyms Application Reactivity