2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N8174
    Valeriandoid F 1427162-60-4 98%
    Valeriandoid F is an iridoid, which potently inhibits NO production with an IC50 value of 0.88 μM. Valeriandoid F has anti-inflammatory and antiproliferative activities.
    Valeriandoid F
  • HY-N8205
    Hispidulin 4'-O-β-D-glucopyranoside 244285-12-9 98%
    Hispidulin 4'-O-β-D-glucopyranosid, a natural compound, may serve as a potential COVID-19 main protease inhibitor.
    Hispidulin 4'-O-β-D-glucopyranoside
  • HY-N8217
    4-O-Cinnamoylquinic acid 5509-70-6 98%
    4-O-Cinnamoylquinic acid could inhibit superoxide anion generation in human neutrophils.
    4-O-Cinnamoylquinic acid
  • HY-N8230
    Ganosinensic acid C 2231756-23-1 98%
    Ganosinensic acid C is a triterpenoid compound that can be extracted from Ganoderma lucidum. Ganosinensic acid C has important biological activities such as anti-tumor, anti-prostate cancer, anti-inflammatory, and inhibition of HIV-I protease. Ganosinensic acid C has an IC50 value of 10.5 μM against human highly metastatic lung cancer cell line 95D. Ganosinensic acid C has an IC50 value of Ganosinensic acid C against cervical cancer cell line Hela is 13.2 μM.
    Ganosinensic acid C
  • HY-N8257
    Dehydrobruceine A 73435-47-9 98%
    Dehydrobruceine A is a low potent antitrypanosomal agent, with an IC50 of 88.5 nM for Plasmodium falciparum.
    Dehydrobruceine A
  • HY-N8263
    Nepetoidin B 55486-06-1 98%
    Nepetoidin B, an anti-inflammatory agent, inhibits inflammation by modulating the NF-κB and Nrf2/HO-1 signaling pathways. Nepetoidin B also has antifungal and antibacterial activity. Nepetoidin B is a natural product that can be obtained from Salvia plebeia R. Br. Nepetoidin B can be used in anti-inflammatory and anti-infectious research.
    Nepetoidin B
  • HY-N8274
    Flavidin 83924-98-5 98%
    Flavidin, an aromatic compound, can be isolated from Coelogyne longipe. Flavidin is an antioxidant, and has radical scavenging activity.
    Flavidin
  • HY-N8311
    Goshonoside F5 90851-28-8 98%
    Goshonoside F5 can be isolated from the unripe fruits of Rubus chingii. Goshonoside F5 has anti-inflammatory activity, and inhibits NF-κB and MAPK signaling pathway.
    Goshonoside F5
  • HY-N8399
    Yadanziolide B 95258-13-2 98%
    Yadanziolide B, a natural quassinoid, is a potential H5N1 neuraminidase inhibitor.
    Yadanziolide B
  • HY-N8415
    Hispanone 82462-67-7 98%
    Hispanone, a diterpenoidcan, has anti-inflammatory activity. Hispanone can be isolated from Leonurus heterophyllus.
    Hispanone
  • HY-N8427
    Bisacurone 120681-81-4 98%
    Bisacurone is a natural terpenoid, exhibits inhibitory activities on LPS-induced NO production with an IC50 of 29.8 μM.
    Bisacurone
  • HY-N8428
    Canophyllal 14440-40-5 98%
    Canophyllal is a triterpene that can be isolated from the leaves of Elsholtzia ciliata. Canophyllal weakly inhibits the production of NO.
    Canophyllal
  • HY-N8449
    Ailanthoidol 156398-61-7 98%
    Ailanthoidol is a natural occurring neolignan, with anti-inflammatory and antitumor activities. Ailanthoidol has chemopreventive activity against tumor promotion.
    Ailanthoidol
  • HY-N8458
    Cryogenine 10308-13-1 98%
    Cryogenine is an alkaloid originally isolated from H. salicifolia that has anti-inflammatory activity. It inhibits prostaglandin synthetase (IC50=424 μM). Cryogenine (100 mg/kg per day, p.o.) reduces paw edema and the mean arthritic index in a rat model of adjuvant-induced polyarthritis.
    Cryogenine
  • HY-N8477
    Isolupalbigenin 162616-70-8 98%
    Isolupalbigenin is an inhibitor of NO. Isolupalbigenin has anti-proliferative activity on HL-60 cells with an IC50 of 5.1 μM.
    Isolupalbigenin
  • HY-N8480
    Atractylochromene 203443-33-8 98%
    Atractylochromene is a potent dual inhibitor of 5-LOX/COX-1 with IC50s of 0.6 and 3.3 μM, respectively.
    Atractylochromene
  • HY-N8529
    Eupalestin 73340-44-0 98%
    Eupalestin is an anti-inflammatory agent. Eupalestin reduces the levels of p-p65 NF-κB and p-p38 MAPK. Eupalestin inhibits MPO and adenosine deaminase. Eupalestin decreases the levels of pro-inflammatory cytokines including IL-17A, IL-6, TNF and IFN-γ. Eupalestin exerts anti-inflammatory activity in a carrageenan (HY-125474)-induced mouse pleurisy model.
    Eupalestin
  • HY-N8604
    Methyl 4-O-caffeoylquinate 123372-74-7 98%
    Methyl 4-O-caffeoylquinate is an extract naturally derived from the leaf ofIlex paraguariensis. Methyl 4-O-caffeoylquinate has human neutrophilic elastase (HNE) inhibitory activity .
    Methyl 4-O-caffeoylquinate
  • HY-N8610
    Uralsaponin D 1262489-44-0 98%
    Uralsaponin D is a saponin that can be isolated from Glycyrrhiza inflata. Uralsaponin D inhibits phospholipase A2 (PLA2) with an IC50 value of 32.2 μM.
    Uralsaponin D
  • HY-N8631
    O-Acetylschisantherin L 149998-51-6 98%
    O-Acetylschisantherin L (Acetylschisantherin L) is a natural lignan, which exhibits inhibitory effects on LPS-induced NO production in BV-2 cells with an IC50 of 23.1 μM.
    O-Acetylschisantherin L
Cat. No. Product Name / Synonyms Application Reactivity