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Cat. No.: HY-N8399

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Yadanziolide B

Yadanziolide B, a natural quassinoid, is a potential H5N1 neuraminidase inhibitor.

For research use only. We do not sell to patients.

CAS No.: 95258-13-2
Formula: C₂₀H₂₆O₁₁
Molecular Weight:442.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Yadanziolide B Chemical Structure

CAS No.: 95258-13-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Yadanziolide B, a natural quassinoid, is a potential H5N1 neuraminidase inhibitor^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
A2780	IC₅₀	>10 μM Compound: 14	Cytotoxicity against human A2780 cells by MTT assay Cytotoxicity against human A2780 cells by MTT assay	[PMID: 22070654]
A549	IC₅₀	3.8 μM Compound: 14	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 22070654]
Bel-7402	IC₅₀	4.24 μM Compound: 14	Cytotoxicity against human Bel7402 cells by MTT assay Cytotoxicity against human Bel7402 cells by MTT assay	[PMID: 22070654]
HCT-8	IC₅₀	3.33 μM Compound: 14	Cytotoxicity against human HCT8 cells by MTT assay Cytotoxicity against human HCT8 cells by MTT assay	[PMID: 22070654]

Chemical Information

CAS No. 95258-13-2
Molecular Weight 442.41
Formula C₂₀H₂₆O₁₁
SMILES

O[C@@]1([C@H]2O)[C@@]([C@@](OC2=O)([H])[C@@H]3O)(CO[C@@]1([C@H]4O)CO)[C@@]([C@H]4O)([H])[C@]([C@]3([H])C(C)=CC5=O)([C@@H]5O)C
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hui Chen, et al. Indole alkaloids and quassinoids from the stems of Brucea mollis. J Nat Prod. 2011 Nov 28;74(11):2438-45. [Content Brief]

[2]. Rina Fajri Nuwarda, et al. Molecular Docking Studies of Compounds from Brucea javanica (L.) Merr. Towards The Discovery of Potential H5N1 Neuraminidase Inhibitors. Beranda Vol 7, No 1 (2020) Nuwarda.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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