1. Natural Products
  2. Plants
  3. Simaroubaceae
  4. Brucea javanica (L.) Merr.

Brucea javanica (L.) Merr.

Brucea javanica (L.) Merr. (19):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-19543
    Brusatol 14907-98-3 99.89%
    Brusatol (NSC 172924) is a unique inhibitor of the Nrf2 pathway that sensitizes a broad spectrum of cancer cells to Cisplatin and other chemotherapeutic agents. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Brusatol can be developed into an adjuvant chemotherapeutic agent. Brusatol increases cellular apoptosis.
  • HY-N3014
    Bruceine D 21499-66-1
    Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity. Bruceine D has strong anthelmintic activity against D. intermedius with an EC50 value of 0.57 mg/L.
    Bruceine D
  • HY-N0840
    Bruceantin 41451-75-6 99.94%
    Bruceantin(NSC165563) is first isolated from Brucea antidysenterica, a tree used in Ethiopia for the treatment of cancer, and activity was observed against B16 melanoma, colon 38, and L1210 and P388 leukemia in mice.
  • HY-N0841
    Bruceine A 25514-31-2 ≥98.0%
    Bruceine A(NSC310616; Dihydrobrusatol) is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.
    Bruceine A
  • HY-N7532
    Yadanzioside I 99132-95-3
    Yadanzioside I is a potent anti-tobacco mosaic virus (TMV) quassinoid with an IC50 of 4.22 μM.
    Yadanzioside I
  • HY-N4257
    Yadanzioside A 95258-15-4 ≥98.0%
    Yadanziolide A, a quassinoid glycoside from Brucea javanica, has antitumor activity.
    Yadanzioside A
  • HY-N7190
    Yadanzioside F 95258-11-0 ≥98.0%
    Yadanzioside F is one of the toxic components found in Brucea javanica. Brucea javanica has demonstrated a variety of antitumoral, antimalarial, and anti-inflammatory properties.
    Yadanzioside F
  • HY-N7189
    Yadanzioside C 95258-16-5
    Yadanzioside C is a quassinoid glucoside found in seeds of Brucea amarissima.
    Yadanzioside C
  • HY-133096
    Yadanzioside K 101559-98-2
    Yadanzioside K is a natural quassinoid glucoside found in Brucea amarissima.
    Yadanzioside K
  • HY-N3015
    Bruceine E 21586-90-3
    Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect. Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ)-induced diabetic rats at lower dose.
    Bruceine E
  • HY-N4210
    Yadanziolide A 95258-14-3 99.41%
    Yadanziolide A, isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC50 of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects.
    Yadanziolide A
  • HY-N8399
    Yadanziolide B 95258-13-2
    Yadanziolide B, a natural quassinoid, is a potential H5N1 neuraminidase inhibitor.
    Yadanziolide B
  • HY-N8995
    Bruceoside A 63306-30-9
    Bruceoside A, an abundant quassinoid glycoside in Fructus Bruceae, possesses anti-cancer activity.
    Bruceoside A
  • HY-N3013
    Bruceine B 25514-29-8
    Bruceine B inhibits protein synthesis and nucleic acid synthesis.
    Bruceine B
  • HY-N7194
    Yadanzioside L 99132-97-5
    Yadanzioside L is a quassinoid and shows anti-tobacco mosaic virus (TMV) activity (IC50=4.86 μM).
    Yadanzioside L
  • HY-N8257
    Dehydrobruceine A 73435-47-9
    Dehydrobruceine A is a low potent antitrypanosomal agent, with an IC50 of 88.5 nM for Plasmodium falciparum.
    Dehydrobruceine A
  • HY-133097
    Yadanzioside M 101559-99-3
    Yadanzioside M is a natural compound with anti-cancer activity.
    Yadanzioside M
  • HY-N7338
    Yadanziolide C 95258-12-1
    Yadanziolide C is a quassinoid with antiproliferative and differentiation-inducing properties in promyelocytic HL-60 cells.
    Yadanziolide C
  • HY-116786
    11-Hydroxycanthin-6-one 75969-83-4
    11-Hydroxycanthin-6-one, a canthin-6-one alkaloid, is an antitumor agent which shows potent cytotoxic activity.