76588-87-9
Chemical Structure
Yadanzigan
Synonym(s): YDZG
- CAS No.: 76588-87-9
- Formula:C26H38O14
- Molecular Weight:574.57
IUPAC Name: (1R,2S,3S,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS,11bR)-1,2,3a,4,11-pentahydroxy-3,8,11a-trimethyl-10-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,2,3,3a,4,6a,7,7a,10,11,11a,11b-dodecahydro-5H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5-one
InChIKey: GLBAPTKVDVXEGQ-DCGYBIAKSA-N
SMILES: CC1=C[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)[C@@H](O)[C@@]3(C)[C@H]1C[C@@H]4[C@]56[C@@H]3[C@@H](O)[C@H](O)[C@@](OC6)(C)[C@]5(O)[C@@H](O)C(O4)=O
Biological Activity: Yadanzigan (YDZG) is an anti-inflammatory agent and a NLRP3 inhibitor. Yadanzigan specifically inhibits NLRP3 activation via inhibiting NF-κB pathway and Reactive Oxygen Species production. Yadanzigan also moderates LPS (HY-D1056)-induced acute lung injury (ALI) in mice[1].
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Yadanzigan | Yadanzigan (YDZG) is an anti-inflammatory agent and a NLRP3 inhibitor. Yadanzigan specifically inhibits NLRP3 activation via inhibiting NF-κB pathway and Reactive Oxygen Species production. Yadanzigan also moderates LPS (HY-D1056)-induced acute lung injury (ALI) in mice. | |||||||||||||||||||||
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