21586-90-3
Chemical Structure
Bruceine E
- CAS 番号: 21586-90-3
- Formula:C20H28O9
- Molecular Weight:412.43
IUPAC Name: (1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS,11bR)-1,2,3a,4,10,11-hexahydroxy-3,8,11a-trimethyl-1,2,3,3a,4,6a,7,7a,10,11,11a,11b-dodecahydro-5H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5-one
InChIKey: ZBXITHPYBBXZRG-QYUWQHSUSA-N
SMILES: CC([C@](C[C@@](O1)2[H])3[H])=C[C@H](O)[C@@H](O)[C@]3(C)[C@]4([H])[C@]2(CO[C@@]5([C@@H](O)[C@@H]4O)C)[C@@]5(O)[C@@H](O)C1=O
Biological Activity: Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect[1]. Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ (HY-13753))-induced diabetic rats at lower dose[2].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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Bruceine E | 97.32% | Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect. Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ (HY-13753))-induced diabetic rats at lower dose. | ||||||||||||||||||||
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- [1]. Man F, et al. HPLC-MS/MS method for bioavailability study of bruceines D & E in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 15;1063:183-188. [Content Brief]
- [2]. Ablat A, et al. Antidiabetic effects of Brucea javanica seeds in type 2 diabetic rats. BMC Complement Altern Med. 2017;17(1):94. Published 2017 Feb 6. [Content Brief]
Keywords
