2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P2564
    Human PD-L1 inhibitor III 2135542-84-4 98%
    Human PD-L1 inhibitor III is a human PD-L1 inhibitor.
    Human PD-L1 inhibitor III
  • HY-P2617
    Ac-WEHD-AFC 210344-99-3 98%
    Ac-WEHD-AFC is a fluorogenic caspase-1 substrate. Ac-WEHD-AFC can measure caspase-1 fluorogenic activity and can be used for the research of tumor and inflammation.
    Ac-WEHD-AFC
  • HY-P2630
    Suc-YVAD-pNA 208264-84-0 98%
    Suc-YVAD-pNA is a substrate of ICE. Interleukin-1β-converting enzyme (ICE) is a cysteine protease responsible for the cleavage of pre-interleukin-1β (pre-IL-1β) to the mature cytokine and a member of a family of related proteases (the caspases).
    Suc-YVAD-pNA
  • HY-P2642
    Peptide 78 132116-62-2 98.13%
    Peptide 78, a chemotactic cytokine, a 78 amino acid protein member of the IL-8 or C-X-C chemokine supergene family. ENA-78 plays an important role in the elicitation of predominantly neutrophils (PMNs) into the joints of rheumatoid arthritis (RA).
    Peptide 78
  • HY-P2674
    KDEL 113516-56-6 98%
    KDEL is a tetrapeptide serving as an endoplasmic reticulum (ER) retrieval/retention signal. KDEL can target and deliver exogenous antigen peptides to the ER, significantly enhance and prolong MHC class I molecule presentation, and effectively boost anti-tumor immune responses.
    KDEL
  • HY-P2710
    Noxiustoxin 85205-49-8 98%
    Noxiustoxin is a toxin from the venom of the Mexican scorpion Centruroides noxius which block voltage-dependent potassium channel (Kv1.3, IC50 = 360 nM), and calcium-activated potassium channel. Noxiustoxin plays an important role in neuroinflammatory disease.
    Noxiustoxin
  • HY-P2712
    Chemerin-9, mouse 686324-96-9 98%
    Chemerin-9, mouse (Chemerin148-156, mouse) is a C-terminal nonapeptide of chemerin. Chemerin-9, mouse is a ligand for ChemR23 (EC50 = 42 nM). Chemerin-9, mouse reduces basal lipolysis in primary mouse white adipocytes(IC50 = 3.3 nM). Chemerin-9, mouse enhances memory and relieves Aβ1-42-induced memory impairment in AD mice. Chemerin-9, mouse also inhibits atherogenesis.
    Chemerin-9, mouse
  • HY-P2781
    3′,5′-Cyclic nucleotide phosphodiesterase 9040-59-9 98%
    3′,5′-Cyclic nucleotide phosphodiesterase is a hydrolytic enzyme that degrades cyclic 3', 5' -adenosine monophosphate (cyclic AMP). 3′,5′-Cyclic nucleotide phosphodiesterase is promising for research of cardiovascular diseases, inflammation, central nervous system disorders, and metabolic syndrome.
    3′,5′-Cyclic nucleotide phosphodiesterase
  • HY-P2791
    Tertiapin (reduced) 58694-52-3 98%
    Tertiapin (reduced) is a kind of synthesis of melittin, its Cys3-Cys14 and Cys5-Cys18 between containing a disulfide bond. Tertiapin (reduced) is a kind of inward rectifier potassium channels blockers, can block the activity of calcium activates large conductance potassium channels. Tertiapin (reduced) can be used for research in diseases such as rheumatoid arthritis and multiple sclerosis.
    Tertiapin (reduced)
  • HY-P2830
    Complement factor D 37213-56-2 98%
    Complement factor D is a serine protease. Complement factor D activates C3 convertase by specifically cleaving complement Factor B. Complement factor D is promising for research of autoimmune diseases (e.g., paroxysmal nocturnal hemoglobinuria, C3 glomerulopathy), age-related macular degeneration, and thrombotic microangiopathies.
    Complement factor D
  • HY-P3073
    Myelin Basic Protein (1-11) 106128-98-7 98%
    Myelin Basic Protein (1-11) is an encephalitogenic epitope of myelin basic protein (MBP). Myelin Basic Protein (1-11) can be used for induction of experimental autoimmune encephalomyelitis (EAE).
    Myelin Basic Protein (1-11)
  • HY-P3083
    N-Myristoyl-Lys-Arg-Thr-Leu-Arg 125678-68-4 98%
    N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor with an IC50 value of 75 μM. N-Myristoyl-Lys-Arg-Thr-Leu-Arg inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat.
    N-Myristoyl-Lys-Arg-Thr-Leu-Arg
  • HY-P3107
    Homodestcardin 917382-84-4 98%
    Homodestcardin, a destruxinbased cyclodepsipeptide, is a immunosuppressant. Homodestcardin, a fungal metabolite, displays pronounced activities against concanavalin A (Con A) activation, with an IC50 value of 0.86 μM.
    Homodestcardin
  • HY-P3129
    KRAS G13D peptide, 25 mer 145019-94-9 98%
    KRAS G13D peptide, 25 mer, a KRAS activating oncogene mutation peptide, is an immune potentiator extracted from patent WO2018144775A1. KRAS G13D peptide, 25 mer can be used to prepare KRAS vaccine.
    KRAS G13D peptide, 25 mer
  • HY-P3130
    Stresscopin-related peptide (human) 348626-74-4 98%
    Stresscopin-related peptide (human) is a specific ligand for the type 2 CRH receptor. Stresscopin-related peptide (human) suppresses food intake, delayed gastric emptying and decreases heat-induced edema. Stresscopin-related peptide (human) maintains homeostasis after stress, and can be used in the research of stress-related diseases.
    Stresscopin-related peptide (human)
  • HY-P3149
    LEESGGGLVQPGGSMK 2096980-79-7 98%
    LEESGGGLVQPGGSMK, a proteolysis peptide, is a component of Infliximab. LEESGGGLVQPGGSMK can be used for quantitative analysis of Infliximab. Infliximab is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α.
    LEESGGGLVQPGGSMK
  • HY-P3168
    Martentoxin 98%
    Martentoxin, a 4,046 Da polypeptide toxin, is a large-conductance Ca2+-activated K+ (BKCa) channel inhibitor. Martentoxin attenuates NO release, inhibits iNOS activation and upregulates eNOS mRNA expression in HUVECs induced by TNF-α. Martentoxin can be used for vascular diseases research.
    Martentoxin
  • HY-P3169
    a-Helical Corticotropin Releasing Factor (9-41) 99658-03-4 98%
    α-Helical Corticotropin Releasing Factor (9-41) is a corticotropin releasing factor (CRF) antagonist. α-Helical Corticotropin Releasing Factor (9-41) decreases plasma growth hormone (GH) values in vivo.
    a-Helical Corticotropin Releasing Factor (9-41)
  • HY-P3174
    Pyroglutamate aminopeptidase I 9075-21-2 98%
    Pyroglutamate aminopeptidase I is a type of enzyme that cleaves the peptide bond of pyroglutamic acid linked to the N-terminal end of a protein, including some important anti-inflammatory proteins like immunoglobulin.
    Pyroglutamate aminopeptidase I
  • HY-P3203
    DSTYSLSSTLTLSK 177792-42-6 98%
    DSTYSLSSTLTLSK is a generic human peptide and can be used for infliximab quantitative detection. Infliximab (Avakine) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α.
    DSTYSLSSTLTLSK
Cat. No. Product Name / Synonyms Application Reactivity