N-Myristoyl-Lys-Arg-Thr-Leu-Arg
N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor with an IC50 value of 75 μM. N-Myristoyl-Lys-Arg-Thr-Leu-Arg inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat.
For research use only. We do not sell to patients.
- CAS No.: 125678-68-4
- Formula: C42H82N12O8
- Molecular Weight:883.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
N-Myristoyl-Lys-Arg-Thr-Leu-Arg (0-50 μM) inhibits the production and release of IL-2 from cultured Jurkat cells stimulated with TPA plus either PHA or OKT3 mAb[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 125678-68-4
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Molecular Weight 883.18
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Formula C42H82N12O8
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Sequence Shortening
Myr-KRTLR
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
N-Myristoyl-Lys-Arg-Thr-Leu-Arg Related Classifications
HY-P3083 Related Classifications
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