Myelin Basic Protein (1-11)
Myelin Basic Protein (1-11) is an encephalitogenic epitope of myelin basic protein (MBP). Myelin Basic Protein (1-11) can be used for induction of experimental autoimmune encephalomyelitis (EAE).
For research use only. We do not sell to patients.
- CAS No.: 106128-98-7
- Formula: C52H88N22O17
- Molecular Weight:1293.39
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Myelin Basic Protein (1-11) (100 μg, i.p.) induced tolerance to MBP in adult mice and prevents MBP-induced EAE[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 106128-98-7
-
Molecular Weight 1293.39
-
Formula C52H88N22O17
-
Sequence Shortening
Ac-ASQKRPSQRHG
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Dittel BN, et al. Presentation of the self antigen myelin basic protein by dendritic cells leads to experimental autoimmune encephalomyelitis. J Immunol. 1999 Jul 1;163(1):32-9. [Content Brief]
[2]. Gaur A, et al. Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy. Science. 1992 Nov 27;258(5087):1491-4. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)