2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-NP0254
    Thyroxin-OVA 98%
    Thyroxin-OVA is a conjugate of Thyroxin (HY-101406) and Ovalbumin (OVA). By conjugating the antigen with protein adjuvants, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt the primary epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.
    Thyroxin-OVA
  • HY-NP0255
    Amoxicillin-BSA 98%
    Amoxicillin-BSA is a conjugate of Amoxicillin (HY-B0467A) and BSA. By conjugating the antigen with protein adjuvants, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt the primary epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.
    Amoxicillin-BSA
  • HY-NP077A
    Phaseolus vulgaris Lectin-P 98%
    Phaseolus vulgaris Lectin-P is the protein form of Phytohemagglutinin before the separation and purification of Phytohemagglutinin-L (PHA-L) and PHA-E. Phaseolus vulgaris Lectin-P can be used to stimulate the proliferation of peripheral mononuclear cells, promote the production of certain cytokines and the expression of membrane surface proteins.
    Phaseolus vulgaris Lectin-P
  • HY-NP078A
    Pisum Sativum Agglutinin (FITC) 98%
    Pisum sativum Agglutinin (PSA) FITC is a plant lectin conjugated with FITC (HY-66019). Pisum sativum Agglutinin FITC serves as an acrosome stain for detecting the acrosomal status of sperm. Pisum sativum Agglutinin exhibits lymphocyte mitogenic and immunomodulatory activities.
    Pisum Sativum Agglutinin (FITC)
  • HY-NP158I
    Collagen Type II (undenatured)
    Collagen Type II (undenatured) is a T-cell dependent antigen with unique immunological features. Type II Collagen, T Cell Grade, from Bovine can be used as a stimulating antigen for T-cells in in vitro culture systems.
    Collagen Type II (undenatured)
  • HY-NP179B
    Pollen extract,ragweed
    Pollen extract,ragweed is an allergen extracted from ragweed samples and can be used as an allergen in allergy research.
    Pollen extract,ragweed
  • HY-NP193A
    Rat IgG Fc fragment 98%
    Rat IgG Fc fragment is a crystallizable fragment (Fc) of rat immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.
    Rat IgG Fc fragment
  • HY-NP193B
    Rat IgG Fab fragment
    Rat IgG Fab fragment is a fragment of antigen (Fab) of rat immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.
    Rat IgG Fab fragment
  • HY-NP194A
    Cyclosporin A-OVA
    Cyclosporin A-OVA is a conjugate of Cyclosporin A (HY-B0579) and OVA. Cyclosporin A is an immunosuppressant which binds to the cyclophilin .
    Cyclosporin A-OVA
  • HY-NP194B
    Cyclosporin A-KLH
    Cyclosporin A-KLH is a conjugate of Cyclosporin A (HY-B0579) and KLH. Cyclosporin A is an immunosuppressant which binds to the cyclophilin .
    Cyclosporin A-KLH
  • HY-P0018C
    Pepstatin acetate 28575-34-0 98%
    Pepstatin (Pepstatin A) acetate is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin acetate also inhibits HIV protease.
    Pepstatin acetate
  • HY-P0018R
    Pepstatin (Standard) 26305-03-3 98%
    Pepstatin (Standard) is the analytical standard of Pepstatin. This product is intended for research and analytical applications. Pepstatin (Pepstatin A) is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin also inhibits HIV protease[1][2].
    Pepstatin (Standard)
  • HY-P0036A
    Octreotide dihydrochloride 1607842-55-6 98%
    Octreotide (SMS 201-995) hydrochloride is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide hydrochloride can bind to the somatostatin receptors which are mainly subtypes 2, 3 and 5. Octreotide hydrochloride increases Gi activity and reduces intracellular cAMP production. Octreotide hydrochloride has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly.
    Octreotide dihydrochloride
  • HY-P0036B
    Octreotide pamoate 135467-16-2 98%
    Octreotide (SMS 201-995) pamoate is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide pamoate can bind to the somatostatin receptors which are mainly subtypes 2, 3 and 5. Octreotide pamoate increases Gi activity and reduces intracellular cAMP production. Octreotide pamoate has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly.
    Octreotide pamoate
  • HY-P0205A
    Saralasin acetate hydrate 39698-78-7 98%
    Saralasin ([Sar1,Ala8] Angiotensin II) acetate hydrate is an octapeptide analog of angiotensin II. Saralasin acetate hydrate is a competitive angiotensin II receptor antagonist with a Ki value of 0.32 nM for 74% of the binding sites, and has partial agonist activity as well. Saralasin acetate hydrate can be used for the research of renovascular hypertension, renin-dependent (angiotensinogenic) hypertension.
    Saralasin acetate hydrate
  • HY-P0295A
    Gly-Arg-Gly-Asp-Ser TFA 2828433-23-2 98%
    Gly-Arg-Gly-Asp-Ser (TFA) is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC50 of ∼5 and ∼6.5 μM.
    Gly-Arg-Gly-Asp-Ser TFA
  • HY-P10021
    Tapderimotide 1221082-45-6 98%
    Tapderimotide (hTERT (691–705)) is an immunological agent for active immunization.
    Tapderimotide
  • HY-P10048
    TAT-JIP 1623722-15-5 98%
    TAT-JIP inhibits the phosphorylation of endogenous c-jun activated by PHA–PMA.
    TAT-JIP
  • HY-P10065
    RKLLW-NH2 289480-71-3 98%
    RKLLW-NH2 is a Cathepsin L inhibitor.
    RKLLW-NH2
  • HY-P10074
    TAT-MEK1 566872-16-0 98%
    TAT-MEK1 is an inhibitor ofERK2, consisting of TAT and MEK1 (N-terminal), TAT (YGRKKRRQRRR) derived from human immunodeficiency (HIV-1) transcriptional trans activator (TAT), is a cell-penetrating peptide. TAT-MEK1 IC50 in vitro for ERK2 is 29 μM.
    TAT-MEK1
Cat. No. Product Name / Synonyms Application Reactivity