2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

Related Products

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N10423
    Cubebin
    		Inhibitor
    Cubebin ((-)-Cubebin), a dibenzyl butyrolactone lignan, is an orally active AChE inhibitor. Cubebin binds to active sites of NF-κB, TNF-α, and TGF-β1 via hydrogen and hydrophobic interactions, obstructing critical residues to inhibit pro-inflammatory or renal fibrosis-related activity. Cubebin enhances p38 MAPK phosphorylation to increase tyrosinase gene expression, stimulating melanogenesis via elevated tyrosinase activity, expression, and mRNA levels. Cubebin reduces oxidative stress via enhanced endogenous antioxidant enzyme activity and inhibited lipid peroxidation, regulates lipid metabolism, improves glycemic control, and exerts renoprotective effects via reduced renal dysfunction markers and improved renal architecture. Cubebin shows antimicrobial activity. Cubebin exerts larvicidal activity against Angiostrongylus cantonensis larvae, with no cytotoxicity toward monkey or human cell lines or Caenorhabditis elegans. Cubebin can be used for the research of diabetic nephropathy, melanoma, colon adenocarcinoma, neuroangiostrongyliasis, Alzheimer’s disease (AD) and depression.
    Cubebin
  • HY-W008923R
    Doxycycline monohydrate (Standard)
    		Inhibitor
    Doxycycline monohydrate (Standard) is the analytical standard of Doxycycline monohydrate (HY-W008923). Doxycycline monohydrate is an orally active highly lipophilic, tissue-permeable MMP inhibitor with broad-spectrum antibacterial activity. Doxycycline monohydrate is also a semi-synthetic antibiotic with chelating properties, which blocks bacterial protein synthesis and inhibits extracellular matrix degradation through interactions with zinc and calcium atoms. Doxycycline monohydrate also inhibits mitochondrial biogenesis, translation, and the expression of respiratory chain proteins. Doxycycline monohydrate induces apoptosis, inhibits autophagy and EMT, downregulates stem cell markers, and activates the PI3K-AKT pathway, thereby effectively inhibiting the viability and proliferation of cancer cells such as breast cancer cells. Doxycycline monohydrate also promotes the survival and self-renewal of embryonic stem cells and neural stem cells, and reduces the frequency of medium changes in culture. Doxycycline monohydrate has been applied in studies related to breast cancer, prostate cancer, bladder cancer, and other cancers.
    Doxycycline monohydrate (Standard)
  • HY-151567
    Antibacterial agent 123
    		Inhibitor
    Antibacterial agent 123 (compound 111) is a potent membrane-disrupting agent to combat antibiotic-resistant Gram-positive bacteria.
    Antibacterial agent 123
  • HY-124236
    Chrysobactin
    		Inhibitor
    Chrysobactin is a compound isolated from the plant pathogenic bacterium Erwinia chrysanthemi. Chrysobactin has siderophore activity.
    Chrysobactin
  • HY-Y1718S2
    Tridecanoic acid-d9
    		Inhibitor
    Tridecanoic acid-d9 is the deuterium labeled Tridecanoic acid. Tridecanoic acid (N-Tridecanoic acid), a 13-carbon medium-chain saturated fatty acid, can serve as an antipersister and antibiofilm agent that may be applied to research bacterial infections. Tridecanoic acid inhibits Escherichia coli persistence and biofilm formation.
    Tridecanoic acid-d<sub>9</sub>
  • HY-126185
    Nibroxane
    		Inhibitor
    Nibroxane is an orally active antibacterial agent. Nibroxane can be metabolized to 2-methyl-5-nitro-m-dioxane in mice.
    Nibroxane
  • HY-B0450AG
    Ciclopirox olamine (GMP)
    		Inhibitor
    Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic.
    Ciclopirox olamine (GMP)
  • HY-N14663
    Griseolic acid C
    		Inhibitor
    Griseolic acid C (Dihydrodeoxygriseolic acid) is an antibiotic. Griseolic acid C can be found in Streptomyces griseoaurantiacus SANK43894. Griseolic acid C has the activity of inhibiting cyclic adenosine monophosphate (cAMP) phosphodiesterase [EC 3.1.4.17] with an IC50 of 0.12 μM (extracted from rat brain).
    Griseolic acid C
  • HY-123175
    Chinfloxacin
    		Inhibitor
    Chinfloxacin is a compound with antibacterial activity. It is active against a variety of clinical isolates in vitro. Its antibacterial activity is similar to that of moxifloxacin, and it has a bactericidal effect in a concentration-dependent manner.
    Chinfloxacin
  • HY-N0849R
    Dictamine (Standard)
    		Inhibitor
    Dictamine (Standard) is the analytical standard of Dictamine. This product is intended for research and analytical applications. Dictamnine (Dictamine) exhibits cytotoxicity to human cervical and colon cancer cells and also has antibacterial and antifungal activities.
    Dictamine (Standard)
  • HY-153771
    Du011
    		Inhibitor
    Du011 is an E. coli polysaccharide capsule biogenesis inhibitor that targets MprA. Du011 can be used in research against E. coli infection.
    Du011
  • HY-B1003A
    Phenethicillin potassium
    		Inhibitor
    Phenethicillin potassium
    Phenethicillin potassium
  • HY-W616426
    3,3'-Bi[1H-indole]
    		Inhibitor
    3,3'-Bi[1H-indole] is a MtbFtsZ inhibitor. 3,3'-Bi[1H-indole] inhibits the GTPase activity of MtbFtsZ. 3,3'-Bi[1H-indole] increases the cell length of Mycobacterium smegmatis and Bacillus subtilis. 3,3'-Bi[1H-indole] can be used in the research of tuberculosis.
    3,3'-Bi[1H-indole]
  • HY-N12179
    Brevianamide M
    		Inhibitor
    Brevianamide M (compound 4) is a metabolite of Aspergillus versicolor. This is an endophytic fungus isolated from the marine brown alga Sargassum. Brevianamide M has antimicrobial activity against Escherichia coli and Staphylococcus aureus.
    Brevianamide M
  • HY-N0059S3
    D-Arabinose-13C-3
    		Inhibitor
    D-Arabinose-13C-3 is the 13C labeled D-Arabinose (HY-N0059). D-Arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-Arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-Arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-Arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-Arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082).
    D-Arabinose-<sup>13</sup>C-3
  • HY-P5619
    Maximin H3
    		Inhibitor
    Maximin H3 is an antimicrobial peptide derived from the skin secretions of Chinese red belly toad Bombina maxima. Maximin H3 has activity against Escherichia coli ATCC25922, Staphylococcus aureus ATCC2592, Bacillus pyocyaneus CMCCB1010 and Candida albicans ATCC2002, the MIC values are 20, 10, 20, 5 μg/ml, respectively.
    Maximin H3
  • HY-139775
    Antibacterial agent 58
    		Inhibitor
    Antibacterial agent 58, an antibacterial agent, significantly lowers MIC value of antibacterial agent Ceftazidime.
    Antibacterial agent 58
  • HY-123214
    Rifametane
    		Inhibitor
    Rifametane is a new 3-azamethyl-rifamycin with a pharmacokinetic profile superior to that of rifampin and activity with peak serum concentrations higher than that of rifampin in healthy volunteers.
    Rifametane
  • HY-N6725R
    Sterigmatocystine (Standard)
    		Inhibitor
    Sterigmatocystine (Standard) is the analytical standard of Sterigmatocystine. This product is intended for research and analytical applications. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor. Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals.
    Sterigmatocystine (Standard)
  • HY-126140
    MDRTB-IN-1
    		Inhibitor
    MDRTB-IN-1 (5aα) is an antibiotic which is against Mycobacterium tuberculosis H37Rv with a MIC90 value of 10.5 μM.
    MDRTB-IN-1
Cat. No. Product Name / Synonyms Application Reactivity