1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-105751
    Kalafungin
    Inhibitor
    Kalafungin is an antibiotic, antimicrobial agent and a β-lactamase inhibitor from marine Streptomyces, with IC50 of 225.37 μM. Kalafungin destroys cell membranes. Kalafungin shows inhibitory activities against a variety of pathogenic fungi, yeasts, protozoa, gram-positive bacteria (such as S. aureus ATCC 33591 and S. aureus ATCC 23591), and, to a lesser extent, gram-negative bacteria.
    Kalafungin
  • HY-W698249R
    Ferrous gluconate (Standard)
    Inhibitor
    Ferrous gluconate (Standard) is the analytical standard of Ferrous gluconate. This product is intended for research and analytical applications. Ferrous gluconate is a highly water-soluble iron-containing agent with high bioavailability and bactericidal activity. As a non-heme iron, Ferrous gluconate is used for meat product fortification and improvement of iron deficiency anemia. Ferrous gluconate induces ferroptosis in E. coli through Fe2+ infiltration, reactive oxygen species burst, lipid peroxidation and direct interaction with DNA. Ferrous gluconate also downregulates the SOS responsive transcriptional repressor LexA. In addition, Ferrous gluconate regulates multiple key pathways in E. coli such as fatty acid metabolism, iron-sulfur cluster assembly and pyruvate metabolism, and is applied in studies related to *E. coli* infection and iron deficiency anemia.
    Ferrous gluconate (Standard)
  • HY-172793
    Antibacterial agent 276
    Inhibitor
    Antibacterial agent 276 (compound B3) is an antibacterial agent with EC50 values of 1.32 μg/mL and 2.80 μg/mL against Xanthomonas oryzae pv.oryzae and Xanthomonas axonopodis pv.citri,respectively. Antibacterial agent 276 disrupts the intracellular redox balance, and results in the accumulation of reactive oxygen species (ROS) and subsequent induction of apoptosis.
    Antibacterial agent 276
  • HY-123412
    FOL7185
    Inhibitor
    FOL7185, an antibacterial agent, is a hit against IspD and IspE enzymes isolated from bacteria.
    FOL7185
  • HY-N14517
    Pacidamycin 4
    Inhibitor
    Pacidamycin 4 has inhibitory effect on Pseudomonas aeruginosa. Pacidamycin 4 also has effect on a few strains of bacteria such as suppurative staphylococcus and Escherichia coli. Serum can reduce its antibacterial activity, pH also affects its antibacterial activity.
    Pacidamycin 4
  • HY-N15420
    Leucomycin A7
    Inhibitor
    Leucomycin A7 is a member of the leucomycin complex that can be isolated from Streptomyces kitasatoensis. Leucomycin A7 has antibacterial activity and has strong inhibitory effects on the growth of Gram-positive bacteria, but weak inhibitory effects on Gram-negative bacteria.
    Leucomycin A7
  • HY-N14522
    Gilvocarcin E
    Inhibitor
    Gilvocarcin E has anti-Gram-positive bacterial activity and can inhibit sarcoma 180 and P388 leukemia cells.
    Gilvocarcin E
  • HY-138179
    7-APRA
    Inhibitor
    7-APRA is a semi-synthetic intermediate of cephalosporin antibiotics. 7-APRA has antibacterial activity and is mainly used in the synthesis of other Cefaclor (HY-B0198) and Cefprozil (HY-B0458A).
    7-APRA
  • HY-N14802
    Napyradiomycin B1
    Inhibitor
    Napyradiomycin B1 is an antibiotic with anti-Gram-positive bacteria and mycobacterial activity. Napyradiomycin B1 almost none to Gram-negative bacteria and fungi. IC50 (μg/mL) of leukemia L-1210 cells is 2.2.
    Napyradiomycin B1
  • HY-101444AR
    PAβN dihydrochloride (Standard)
    Inhibitor
    PAβN (dihydrochloride) (Standard) is the analytical standard of PAβN (dihydrochloride) (HY-101444A). This product is intended for research and analytical applications. PAβN dihydrochloride (MC-207110 dihydrochloride) is an efflux pump inhibitor.
    PAβN dihydrochloride (Standard)
  • HY-182364
    T3SS-IN-6
    Inhibitor
    T3SS-IN-6 is a thiazolidin-2-cyanamide derivative and type III secretion system (T3SS) inhibitor targeting Xanthomonas oryzae pv. oryzae (Xoo). T3SS-IN-6 exhibits no effect on Xoo growth. T3SS-IN-6 shows no measurable acute toxicity to silkworms and earthworms.
    T3SS-IN-6
  • HY-119839
    Acediasulfone
    Inhibitor
    Acediasulfone is an antimicrobial. Acediasulfone can formation of a colored product reaction with p-dimethylaminobenzaldehyde.
    Acediasulfone
  • HY-N14875
    Fumaryl-DL-alanine
    Inhibitor
    Fumaryl-DL-alanine has anti-Gram-positive bacterial activity.
    Fumaryl-DL-alanine
  • HY-122381R
    Kyotorphin (Standard)
    Inhibitor
    Kyotorphin (Standard) is the analytical standard of Kyotorphin. This product is intended for research and analytical applications. Kyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the progression of neurodegeneration in Alzheimer's Disease patients.
    Kyotorphin (Standard)
  • HY-B1050R
    Gemifloxacin mesylate (Standard)
    Inhibitor
    Gemifloxacin (mesylate) (Standard) is the analytical standard of Gemifloxacin (mesylate). This product is intended for research and analytical applications. Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections.
    Gemifloxacin mesylate (Standard)
  • HY-123219
    Salifluor
    Inhibitor
    Salifluor is a broad spectrum antimicrobial agent that has been investigated for its abilities to inhibit dental plaque formation. Salifluor can act as an effective anti-inflammatory agent.
    Salifluor
  • HY-177949
    ETX1317
    Inhibitor
    ETX1317 is a β-lactamase inhibitor that restores the antibacterial activity of several classes of β-lactam antibiotics, including third-generation cephalosporins such as Cefpodoxime (HY-A0251). ETX1317 can be used for research on bacterial infection.
    ETX1317
  • HY-148851
    Bacteriochlorophyll a, from Rhodopseudomonas sphaeroides (under argon)
    Inhibitor
    Bacteriochlorophyll a, from Rhodopseudomonas sphaeroides (under argon) (BChl a, from Rhodopseudomonas sphaeroides (under argon)) is a chlorophyll analog found in some bacteria that participates in the light absorption and energy transfer processes of photosynthesis.
    Bacteriochlorophyll a, from Rhodopseudomonas sphaeroides (under argon)
  • HY-N14201
    Maridomycin IV
    Inhibitor
    Maridomycin IV is a macrolide antibiotic. Maridomycin IV has the activity against Gram-positive bacteria and mycoplasma. Maridomycin IV has the effect of protecting Gram-positive bacterial infection mice.
    Maridomycin IV
  • HY-121497R
    3-Methoxybenzamide (Standard)
    Inhibitor
    3-Methoxybenzamide (Standard) is the analytical standard of 3-Methoxybenzamide. This product is intended for research and analytical applications. 3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum).
    3-Methoxybenzamide (Standard)
Cat. No. Product Name / Synonyms Application Reactivity