1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W026339
    IMB-XMA0038
    Inhibitor
    IMB-XMA0038 is a MtASADH inhibitor with an IC50 value of 0.59 μg/mL. IMB-XMA0038 inhibits various agent-resistant Mycobacteria tuberculosis potently with MICs of 0.25-0.5 μg/mL. IMB-XMA0038 shows anti-tuberculosis activity.
    IMB-XMA0038
  • HY-A0241A
    Dalfopristin mesylate
    Inhibitor
    Dalfopristin (RP54476) mesylate is a semisynthetic sulfone antibiotic. Dalfopristin mesylate alone has limited antibacterial activity, but synergistically with Quinupristin it has significant bactericidal activity against many pathogenic Gram-positive cocci.
    Dalfopristin mesylate
  • HY-N14029
    Coriolin B
    Inhibitor
    Coriolin B has anti-Gram-positive bacteria, negative bacteria (weak), yeast and vaginal trichomoniasis activities. Coriolin B of 5 μg/mL can inhibit the growth of yoshida sarcoma 61.6%. Coriolin B has no inhibitory effect on Ehrlich ascites carcinoma in animals.
    Coriolin B
  • HY-119675
    Albonoursin
    Inhibitor
    Albonoursin, a microbial secondary metabolite, is an antibacterial peptide. Albonoursin displays antibacterial and antitumor activities.
    Albonoursin
  • HY-B1454R
    Clindamycin palmitate hydrochloride (Standard)
    Inhibitor
    Clindamycin palmitate (hydrochloride) (Standard) is the analytical standard of Clindamycin palmitate (hydrochloride). This product is intended for research and analytical applications. Clindamycin palmitate hydrochloride is a hydrochloride salt of the ester of clindamycin and palmitic acid and it is an antibacterial agent. Clindamycin palmitate hydrochloride is inactive in vitro, rapid in vivo hydrolysis converts this compound to the antibacterially active clindamycin.
    Clindamycin palmitate hydrochloride (Standard)
  • HY-N14100
    Pyloricidin D
    Inhibitor
    Pyloricidin D is an antibiotic against Helicobacter pylori found in Bacillus sp. HC-70.
    Pyloricidin D
  • HY-174313
    Antibacterial agent 284
    Inhibitor
    Antibacterial agent 284 (Compound 7) is an Antibacterial agent. Antibacterial agent 284 has a zinc-binding structure and potent inhibitory activity against Legionella pneumophila metalloprotease ProA (IC50: 0.96 μM) with zinc-binding structure. Antibacterial agent 284 significantly inactivates the cleavage of collagen IV and flagellin (ProA substrates) and reduces immune evasion from the TLR5-NF-κB pathway and PMN-mediated inflammation in human lung tissue explants. Antibacterial agent 284 is promising for Legionnaires' disease research.
    Antibacterial agent 284
  • HY-169571
    Antimicrobial agent-38
    Inhibitor
    Antimicrobial agent-38 (compound 10) is a potent inhibitor of methicillin-resistant S. aureus strain ATCC 700699 and nonresistant strain ATCC 29213, with MICs of 32 and 64 mg/L.
    Antimicrobial agent-38
  • HY-122448A
    (Rac)-Sativan
    Inhibitor
    (Rac)-Sativan is an isoflavanoid with a broad spectrum of antimicrobial activity against bacteria and phytopathogenic fungi. (Rac)-Sativan exhibits antituberculosis activity against Mycobacterium tuberculosis H37Rv, with MIC values of 50 µg/mL.
    (Rac)-Sativan
  • HY-120235
    CB-618
    Inhibitor
    CB-618 is a β-lactamase inhibitor. CB-618 reversibly covalently inhibits Ambler class A, C, and some class D serine β-lactamases. CB-618 has weak antibacterial activity as a single agent, but it significantly enhances the antibacterial activity of Meropenem (HY-13678) against enzyme-producing Enterobacteriaceae. CB-618 can be used in research on drug-resistant bacteria.
    CB-618
  • HY-N8443S
    Isoaltenuene-d6
    Inhibitor
    Isoaltenuene-d6 is deuterium labeled Isoaltenuene. Isoaltenuene is an anti-bacterial agent with moderate activity against Staphylococcus aureus. Isoaltenuene can be isolated from fungus Alternaria alternate cib-137.
    Isoaltenuene-d<sub>6</sub>
  • HY-W104752
    5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol
    Inhibitor 99.34%
    5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol (Compound 3n) is an antimicrobial and antioxidant agent, that inhibits Escherichia coli and Staphylococcus epidermidis, with MIC of 8 and 4 μg/mL. 5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol exhibits antioxidant activity with IC50 of 17.47 μM using DPPH free radical-scavenging method.
    5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol
  • HY-161813
    Antibacterial agent 229
    Inhibitor
    Antibacterial agent 229 (compound 8a) is a potent antibacterial agent. Antibacterial agent 229 shows antibacterial and antifungal abilities. Antibacterial agent 229 disrupts the integrity of the bacterial membrane, intercalates into DNA. Antibacterial agent 229 inhibits topoisomerase IV with an IC50 value of 10.88 µM.
    Antibacterial agent 229
  • HY-108939R
    Aminoacyl tRNA synthetase-IN-1 (Standard)
    Inhibitor
    Aminoacyl tRNA synthetase-IN-1 (Standard) is the analytical standard of Aminoacyl tRNA synthetase-IN-1 (HY-108939). This product is intended for research and analytical applications. Aminoacyl tRNA synthetase-IN-1 is a bacterial aminoacyl tRNA synthetase (aaRS) inhibitor. Aminoacyl tRNA synthetase-IN-1 has inhibitory activity against S. aureus, E. faecalis and E.coli.
    Aminoacyl tRNA synthetase-IN-1 (Standard)
  • HY-170991
    C12-rrw-NH2
    Inhibitor
    C12-rrw-NH2 (Compound Lip7) is an antibacterial agent against gram-positive bacteria, especially against Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). C12-rrw-NH2 induces bacterial death via depolarizing the bacterial cytoplasmic membrane, disrupting the integrity of the bacterial membrane, leading to leakage of nucleic acid and protein and promoting the generation of Reactive Oxygen Species. C12-rrw-NH2 is potential to be used for research of developing high-stability antimicrobial peptides.
    C12-rrw-NH2
  • HY-180115
    Antibacterial agent 315
    Inhibitor
    LP07 is an antibacterial agent targeting Pseudomonas aeruginosa with MIC values for both wild-type and efflux pump-deficient P. aeruginosa PA14 of both 8 μg/mL. LP07 exerts its antibacterial effect by directly disrupting the structural integrity of the bacterial cell membrane. LP07 moderately inhibits MMP-17 and MMP-19, but has no significant inhibitory effect on other MMP subtypes. LP07 does not inhibit the activity of LpxC enzyme. LP07 can be used for research on Pseudomonas aeruginosa infections.
    Antibacterial agent 315
  • HY-155460
    Pks13-TE inhibitor 4
    Inhibitor
    Pks13-TE inhibitor 4 (compound 44) is an oxadiazole series Pks13 inhibitor that effectively inhibits tuberculosis (TB) and resolves its drug resistance.
    Pks13-TE inhibitor 4
  • HY-N14370
    Menoxymycin A
    Inhibitor
    Menoxymycin A is an antibiotic. Menoxymycin A has a cytotoxic effect. Menoxymycin A inhibits KB and N18-RE-105 cells with IC50s of 0.86 μM and 0.14 μM.
    Menoxymycin A
  • HY-125416
    Streptothricin F
    Inhibitor 98.34%
    Streptothricin F is a bactericidal antibiotic. Streptothricin F interacts with the 30S subunit of 70S ribosome. Streptothricin F shows rapid, bactericidal activity against highly drug-resistant, carbapenem-resistant Enterobacterales (CRE) (MIC50 and MIC90: 2 and 4 μM, respectively) and Acinetobacter baumannii.
    Streptothricin F
  • HY-125455
    Ro 41-1879
    Inhibitor
    Ro 41-1879 is a catechol cephalosporin that has antimicrobial activity.
    Ro 41-1879
Cat. No. Product Name / Synonyms Application Reactivity