5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol
Based on 1 Customer Validation
5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol (Compound 3n) is an antimicrobial and antioxidant agent, that inhibits Escherichia coli and Staphylococcus epidermidis, with MIC of 8 and 4 μg/mL. 5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol exhibits antioxidant activity with IC50 of 17.47 μM using DPPH free radical-scavenging method.
For research use only. We do not sell to patients.
- Purity : 99.34%
- CAS No.: 15264-63-8
- Formula: C7H5N3OS
- Molecular Weight:179.20
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
>250 μM
Compound: 9
|
Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 22309914] |
Chemical Information
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CAS No. 15264-63-8
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Appearance Solid
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Molecular Weight 179.20
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Formula C7H5N3OS
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Color Light yellow to yellow
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SMILES
C1=C(C=CN=C1)C2=NN=C(O2)S
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- 5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol
- 15264-63-8
- Free Radical Scavengers
- Bacterial
- Fungal
- Candida albicans
- Aspergillus fumigatus
- Fusarium oxysporum
- Pseudomonas aeruginosa
- Escherichia coli
- Acinetobacter baumannii
- Streptococcus pneumoniae
- Staphylococcus epidermidis
- Bacillus cereus
- Alzheimer’s Disease
- Parkinson’s Disease
- diabetic
- Inhibitor
- inhibitor
- inhibit