1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14281
    Himalomycin B
    Inhibitor
    Himalomycin B is an anthraquinone antibiotic. Himalomycin B has strong activity against Staphylococcus aureus, Escherichia coli and Streptomyces vuridochromogenes.
    Himalomycin B
  • HY-N15393
    Cerexin B4
    Inhibitor
    Cerexin B4 has anti-Gram-positive bacterial activity.
    Cerexin B4
  • HY-159929
    Antibiotic adjuvant 2
    Inhibitor
    Antibiotic adjuvant 2 (compound 5q) is an antibiotic adjuvant with potent colistin-potentiating activity and low mammalian toxicity. Antibiotic adjuvant 2 has minimum re-sensitizing concentration of 0.125 μg/mL agnist of Escherichia coli AR-0493.
    Antibiotic adjuvant 2
  • HY-W392548
    1-O-(4-Hydroxybenzoyl)-glycerol
    Inhibitor
    1-O-4-Hydroxybenzoyl-glycerol is an antimicrobial agent against Staphylococcus aureus, Escherichia coli, Saccharomyces cerevisiae, and Fusarium culmorum (20 mM, maximum inhibition rate: 70%). 1-O-(4-Hydroxybenzoyl)-glycerol stimulates low skin irritation.
    1-O-(4-Hydroxybenzoyl)-glycerol
  • HY-N14210
    Epithienamycin F
    Inhibitor
    Epithienamycin F is a carbapenem antibiotic. Epithienamycin F has anti-Gram-positive bacteria and anti-Gram-negative bacteria activity.
    Epithienamycin F
  • HY-N14705
    2-Hydroxygentamicin C2
    Inhibitor
    2-Hydroxygentamicin C2 is an antibiotic of the gentamicin group with anti-Gram-positive and negative bacteria activity.
    2-Hydroxygentamicin C2
  • HY-W783358
    Pefloxacin impurity 1
    Inhibitor
    Pefloxacin impurity 1 (Pefloxacin impurity B) is an antibacterial agent. Pefloxacin impurity 1 exhibits in vitro antibacterial activity against Gram-positive and Gram-negative bacteria.
    Pefloxacin impurity 1
  • HY-170802
    Anti-MRSA agent 22
    Inhibitor
    Anti-MRSA agent 22 (Compound 5a) is a potent antibacterial agent against MRSA with a MIC value of 6 µg/mL. Anti-MRSA agent 22 exhibits high binding affinity (−11.19) to FabI.
    Anti-MRSA agent 22
  • HY-15306AR
    Eltrombopag Olamine (Standard)
    Inhibitor
    Eltrombopag (Olamine) (Standard) is the analytical standard of Eltrombopag (Olamine). This product is intended for research and analytical applications. Eltrombopag Olamine (Eltrombopag diethanolamine salt) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag Olamine owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag Olamine can be used for the research of cardiovascular. Eltrombopag Olamine also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag Olamine can induce apoptosis in hepatocellular carcinomab (HCC) as well.
    Eltrombopag Olamine (Standard)
  • HY-B0398S
    Nalidixic Acid-d5
    Inhibitor
    Nalidixic Acid-d5 is the deuterium labeled Nalidixic acid. Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria.
    Nalidixic Acid-d<sub>5</sub>
  • HY-123156
    SC-23110
    Inhibitor
    SC-23110 is a potent anti-acne agent. SC-23110 inhibits the growth of P. acnes, one of the organisms associated with acne, and most frequently mentioned as the organism involved in the pathogenesis of inflammatory pustules/lesions.
    SC-23110
  • HY-179670
    Antibacterial agent 304
    Inhibitor
    Antibacterial agent 304 (Compound 3a) is an antibacterial agent with a minimum inhibitory concentration (MIC) of 8 μg/mL against S. aureus and P. aeruginosa. This antibacterial agent has a bactericidal effect and can disrupt the integrity of the cell wall. Antibacterial agent 304 has the potential to be a sustainable organic photocatalyst.
    Antibacterial agent 304
  • HY-P1674
    Murepavadin
    Inhibitor
    Murepavadin (POL7080), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with both MIC50 and MIC90 values of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance.
    Murepavadin
  • HY-N15356
    9-Oxooctadecanedioic acid
    Inhibitor
    9-Oxooctadecanedioic acid is an α,ω-dicarboxylic fatty acid monomer found in the cork suberin of Quercus suber. It contributes to the formation of the hydrophobic barrier structure in plant cell walls and may play an important role in functions such as water resistance and protection against microbial penetration.
    9-Oxooctadecanedioic acid
  • HY-163716
    Antibacterial agent 222
    Inhibitor
    Antibacterial agent 222 ((R)-O30 (5)) is a antimicrobial agent that inhibits methicillin-resistant Staphylococcus aureus (MRSA).
    Antibacterial agent 222
  • HY-117250
    EcDsbB-IN-10
    Inhibitor 98.71%
    EcDsbB-IN-10 (compound 12) is an inhibitor of EcDsbB (E. coli DsbB) enzyme, with a Ki of 0.8 nM and an IC50 of 18.85 nM.
    EcDsbB-IN-10
  • HY-161756
    DNA Gyrase-IN-10
    Inhibitor
    DNA Gyrase-IN-10 is a potent DNA gyrase inhibitor with potent antibacterial effects. DNA Gyrase-IN-10 has inhibitory effects on both Gram-positive and Gram-negative bacteria.
    DNA Gyrase-IN-10
  • HY-B0512S
    Sulfamerazine-d4
    Inhibitor 99.00%
    Sulfamerazine-d4 is a deuterium labeled Sulfamerazine. Sulfamerazine (RP2632) is a brain-penetrant and orally active sulfonamide antibiotic and α-synuclein inhibitor with human α-synuclein KD of 352 μM. Sulfamerazine inhibits the synthesis of dihydrofolate by bacteria, thereby inhibiting bacterial growth. Sulfamerazine inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine can be used for the research of Parkinson’s disease and bacterial infection.
    Sulfamerazine-d<sub>4</sub>
  • HY-N12261
    Benastatin B
    Inhibitor
    Benastatin B is an inhibitor for glutathione S-transferase, that inhibits human pi class GST with an IC50 of 1.10 μg/mL. Benastatin B exhibits board-spectrum antibacterial efficacy, inhibits MRSA with MIC 3.1 μg/mL. Benastatin B exhibits anti-inflammatory efficacy through inhibition of IgE mediated β-hexosaminidase release with an IC50 of 79 μg/mL.
    Benastatin B
  • HY-B1275R
    Cephalothin sodium (Standard)
    Inhibitor
    Cephalothin (Cephalotin) sodium (Standard) is the analytical standard of Cephalothin sodium (HY-B1275). This product is intended for research and analytical applications. Cephalothin sodium is a semi-synthetic cephalosporin antibiotic and beta-lactam antibiotic. Cephalothin inhibits class C β-lactamase AmpC, with an Ki of 0.32 µM. Cephalothin sodium binds to penicillin-binding proteins, interfering with the cross-linking of peptidoglycan in the cell wall and thus hindering the normal synthesis of the bacterial cell wall. Cephalothin sodium shows antibacterial activity against a variety of bacteria. Cephalothin sodium can be used in hematological and nephrotoxicity studies.
    Cephalothin sodium (Standard)
Cat. No. Product Name / Synonyms Application Reactivity