Benastatin B
Benastatin B is an inhibitor for glutathione S-transferase, that inhibits human pi class GST with an IC50 of 1.10 μg/mL. Benastatin B exhibits board-spectrum antibacterial efficacy, inhibits MRSA with MIC 3.1 μg/mL. Benastatin B exhibits anti-inflammatory efficacy through inhibition of IgE mediated β-hexosaminidase release with an IC50 of 79 μg/mL.
For research use only. We do not sell to patients.
- CAS No.: 138968-86-2
- Formula: C30H30O7
- Molecular Weight:502.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 138968-86-2
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Molecular Weight 502.56
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Formula C30H30O7
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SMILES
O=C(C1=C(C2=C(C=C1CCCCC)CCC3=C2C=C4C(C(C5=C(C4(C)C)C=C(O)C=C5O)=O)=C3O)O)O
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Structure Classification
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Initial Source
Streptomyces sp. MI384-DF12
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Aoyama T, et al., Benastatins A and B, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. II. Structure determination of benastatins A and B. J Antibiot (Tokyo). 1992 Sep;45(9):1391-6. [Content Brief]
[2]. Tsakem B, et al., Structures, biosynthesis and biological activities of benastatins, anthrabenzoxocinones and fredericamycins. Bioorg Chem. 2024 Sep;150:107572. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Benastatin B Related Classifications
HY-N12261 Related Classifications
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