2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-181866
    Antibacterial agent 328
    		Inhibitor
    Antibacterial agent 328 is a enoyl-ACP reductase (InhA) inhibitor and antimycobacterial agent. Antibacterial agent 328 blocks mycolic acid biosynthesis in Mycobacterium tuberculosis. Antibacterial agent 328 acts on both drug-resistant and drug-susceptible Mycobacterium tuberculosis strains. Antibacterial agent 328 exhibits favorable pharmacokinetic properties, drug-likeness, and a safety-related selectivity index. Antibacterial agent 328 can be used for research on tuberculosis.
    Antibacterial agent 328
  • HY-119648
    CCR-11
    		Inhibitor
    CCR-11 is an antibacterial agent. CCR-11 can inhibit the proliferation of B. subtilis cells with an IC50 value of 1.2 μM. CCR-11 inhibits HeLa cell proliferation with an IC50 value of 18.1 μM. CCR-11 inhibits bacterial cytokinesis by inhibiting FtsZ assembly. CCR-11 can be used for the research of FtsZ-targeted antibacterial agents.
    CCR-11
  • HY-N13983
    Arylomycin B4
    		Inhibitor
    Arylomycin B4 is a lipohexapeptide antibiotic against Gram-positive bacteria.
    Arylomycin B4
  • HY-180215
    NuoD-IN-1
    		Inhibitor
    NuoD-IN-1 (Compound 56) is a NuoD inhibitor and antibacterial agent. NuoD-IN-1 exhibits potent antibacterial activity against F. tularensis LVS with a MIC of 0.03125 μg/mL.
    NuoD-IN-1
  • HY-162624
    Quorum sensing-IN-5
    		Inhibitor
    Quorum sensing-IN-5 is a RpfF-targeted quorum-sensing inhibitor. Quorum sensing-IN-5 inhibits Xanthomonas oryzae pv oryzae (Xoo) and Xanthomonas axonopodis pv. citri (Xac) with EC50 values of 9.91 μg/mL and 7.04 μg/mL. Quorum sensing-IN-5 has antimicrobial activity.
    Quorum sensing-IN-5
  • HY-W012088
    (Z)-Methyl tetradec-9-enoate
    		Inhibitor 98.24%
    (Z)-Methyl tetradec-9-enoate (Myristoleic acid methyl ester; Methyl myristoleate) is a cytotoxic component extracted from S. repens fruit extract. It induces apoptosis and necrosis in human prostate cancer LNCaP cells. In addition, (Z)-Methyl tetradec-9-enoate found in cheese-making byproducts inhibits Candida albicans germination with a minimum inhibitory concentration (MIC) of 9 μM in vivo.
    (Z)-Methyl tetradec-9-enoate
  • HY-N16435
    Plumericin
    		Inhibitor
    Plumericin is an anti-inflammatory, antioxidant, and antibacterial agent. Plumericin reduces Apoptosis, promotes Nrf-2 and inhibits NF-κB and AhR activation, blocks STAT3 signaling. Plumericin inhibits Mycobacterium tuberculosis growth. Plumericin can be used for the research of chronic kidney disease, vascular diseases, inflammatory bowel diseases, peritonitis, and tuberculosis.
    Plumericin
  • HY-N14996
    6-Deoxyparomomycin
    		Inhibitor
    6-Deoxyparomomycin is found in the strain of Streptomyces rimosus forma paromomycinus with antibacterial activity.
    6-Deoxyparomomycin
  • HY-181674
    ZHO-197
    		Inhibitor
    ZHO-197 is a dual bacterial peptide deformylase and methionine aminopeptidase inhibitor with antibacterial activity. ZHO-197 exhibits an Escherichia coli peptide deformylase IC50 of 0.021 μM and a human peptide deformylase IC50 of 3.289 μM. ZHO-197 displays broad-spectrum antibacterial activity against gram-positive and gram-negative bacterial strains. ZHO-197 can be used for the research of bacterial infection.
    ZHO-197
  • HY-B1358R
    Lincomycin hydrochloride monohydrate (Standard)
    		Inhibitor
    Lincomycin (U-10149) hydrochloride monohydrate (Standard) is the analytical standard of Lincomycin hydrochloride monohydrate (HY-B1358). This product is intended for research and analytical applications. Lincomycin hydrochloride monohydrate is an orally active lincosamide antibiotic. Lincomycin hydrochloride monohydrate binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin hydrochloride monohydrate can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin hydrochloride monohydrate induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice.
    Lincomycin hydrochloride monohydrate (Standard)
  • HY-163769
    DUB-IN-8
    		Inhibitor
    DUB-IN-8 (Compound 8q) is an inhibitor for Chlamydia deubiquitinase 1 (DUB1), with IC50 of 7.7 μM. DUB-IN-8 exhibits antimicrobial activity, inhibits the chlamydial inclusions with an IIC50 (the concentration to induce 50% inclusion inhibition) of 8.5 μg/mL.
    DUB-IN-8
  • HY-N14011
    Cedarmycin A
    		Inhibitor
    Cedarmycin A has activities against Candida, Cryptococcus neoforme and Aspergillus fumigatus, with the MIC values of 12.5-50 μg/mL.
    Cedarmycin A
  • HY-B0724B
    Pazufloxacin
    		Inhibitor
    Pazufloxacin is an orally active fluoroquinolone antimicrobial agent. Pazufloxacin inhibits DNA gyrase with IC50 values of 0.88 μg/mL (E. coli) and 1.9 μg/mL (P. aeruginosa). Pazufloxacin exhibits broad-spectrum antimicrobial activity, with MIC90 values ranging from 0.025 to 100 μg/mL against Gram-positive and Gram-negative bacteria, non-fermenting bacteria, Legionella spp., and anaerobic bacteria. Pazufloxacin is indicated for research on systemic infections, lung infections, urinary tract infections, and Legionella pneumonia.
    Pazufloxacin
  • HY-N14726
    Primocarcin
    		Inhibitor
    Primocarcin is an antibiotic that inhibits Ehrlich ascites cancer.
    Primocarcin
  • HY-402733
    Antibacterial agent 300
    		Inhibitor
    Antibacterial agent 300 ((S)-3-[4-(Methylthio)phenyl]-2-oxo-5-(aminomethyl)-oxazolidine) is an aminomethyl oxooxazolidinyl benzene derivative, with antibacterial activity.
    Antibacterial agent 300
  • HY-180328
    3''-Deamino-3''-hydroxykanamycin B
    		Inhibitor
    3''-Deamino-3''-hydroxykanamycin B (NK-1012-1) is a kanamycin antibiotic. 3''-Deamino-3''-hydroxykanamycin B can be produced by S. tenebrarius. 3''-Deamino-3''-hydroxykanamycin B is effective against E. coli ATCC 25922 and E. coli CCARM 1A020, with MIC values of 128 μg/mL.
    3''-Deamino-3''-hydroxykanamycin B
  • HY-173528
    Antimicrobial agent-40
    		Inhibitor
    Antimicrobial agent-40 (Compound 5a) has antimicrobial activity against fungi, Gram-negative and Gram-positive bacteria. Antimicrobial agent-40 has good cytotoxicity against MCF-7 cells (IC50: 33.52 μM) and exhibits anticancer activity.
    Antimicrobial agent-40
  • HY-13766A
    Timcodar mesylate
    		Inhibitor
    Timcodar mesylate (VX-853-2) and its analog VX-710 are mammalian multidrug-resistant bacterial efflux pump inhibitors that directly inhibit ethidium bromide efflux in Staphylococcus aureus. Timcodar mesylate has the potential to enhance antibiotic activity by inhibiting bacterial efflux pumps, effectively reducing the minimum inhibitory concentration of some antibiotics against Gram-positive pathogens such as Staphylococcus aureus, Enterococcus and Streptococcus pneumoniae.
    Timcodar mesylate
  • HY-113718
    DS21412020
    		Inhibitor
    DS21412020 is a fluoroquinolone antibacterial agent. DS21412020 inhibits bacterial DNA gyrase (GyrA) and topoisomerase IV, leading to DNA breaks. DS21412020 exhibits significant activity against Gram-positive bacteria such as Staphylococcus aureus (MIC = 0.006 μg/mL), Streptococcus pneumoniae (MIC = 0.05 μg/mL), and Methicillin (HY-121544)-resistant Staphylococcus aureus (MIC = 0.2 μg/mL), and Gram-negative bacteria such as Escherichia coli (MIC = 0.006 μg/mL) and Pseudomonas aeruginosa (MIC = 0.78 μg/mL). DS21412020 significantly reduces bacterial load in mouse pneumonia and MRSA infection models. DS21412020 can be used in the development of next-generation quinolone antibiotics.
    DS21412020
  • HY-N16672
    SMTP-0
    		Inhibitor
    SMTP-0 (ent-Stachybotrin B) is an enantiomer of Stachybotrin B isolated from Stachybotrys microspora. SMTP-0 is the simple homologues of the SMTP nonlysine-analog plasminogen modulator family but shows no plasminogen modulator activity. SMTP-0 exhibits antibacterial and antifungal effects. SMTP-0 can be used for the research of infection.
    SMTP-0
Cat. No. Product Name / Synonyms Application Reactivity