2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-167812
    Trimethylsilyl-L-(+)-rhamnose
    		Inhibitor
    Trimethylsilyl-L-(+)-rhamnose is a chemically modified version of the natural sugar rhamnose that has activity in studying the role of rhamnose in bacterial cell walls. Trimethylsilyl-L-(+)-rhamnose can be used to explore the composition of bacterial cell walls and their biological functions. Trimethylsilyl-L-(+)-rhamnose can help scientists gain insight into bacterial growth and resistance mechanisms.
    Trimethylsilyl-L-(+)-rhamnose
  • HY-P5706
    HG2
    		Inhibitor
    HG2 is a fast-acting antimicrobial peptide. HG2 shows anti-biofilm and anti-inflammatory activities. HG2 is active against Gram-positive pathogens, especially against MRSA strains (MIC: 16-32 μg/mL). HG2 can bind to bacterial lipids and reduces ATP concentration in S. aureus MRSA USA300 cells.
    HG2
  • HY-P0135
    Penta lysine
    		Inhibitor
    Penta lysine is an antibacterial agent, that inhibits E. coli, A. baumannii, P. aeruginos, S. aureus, and B. subtilis, with MIC of 1.1-18 μM.
    Penta lysine
  • HY-179026
    HCA-6
    		Inhibitor
    HCA-6 is a calcium-channel and P-glycoprotein blocker. HCA-6 can induce cancer cells apoptosis and increase anticancer activity of Cisplatin (HY-17394). HCA-6 also exhibits antibacterial activity against Bacillus subtilis. HCA-6 can be used for the research of cancer and infection, such as breast cancer.
    HCA-6
  • HY-168705
    Anti-MRSA agent 20
    		Inhibitor
    Anti-MRSA agent 20 (Compound a4) is an anti-microbial agent (MIC: < 0.03125 μg/mL) against MRSA). Anti-MRSA agent 20 binds to the ribosomal peptidyl transferase center and inhibits bacterial survival by inhibiting MRSA toxin synthesis and bacterial division. Anti-MRSA agent 20 significantly reduces the MRSA load in the lungs and attenuates lung injury in the MRSA-infected mice (ED50 = 6.48 mg/kg).
    Anti-MRSA agent 20
  • HY-P2661A
    FA-Leu-Gly-Pro-Ala-OH TFA
    FA-Leu-Gly-Pro-Ala-OH TFA is a furylacryloyl-terminal tetrapeptide that serves as a substrate for bacterial collagenase and spirochete metalloendopeptidase. FA-Leu-Gly-Pro-Ala-OH TFA is specifically hydrolyzed by spirochete collagenase only at the Leu-Gly bond. FA-Leu-Gly-Pro-Ala-OH TFA can be used to determine the equilibrium constant of peptide bond hydrolysis, and also to detect collagenase-mediated cleavage reactions via turbidimetry based on absorbance reduction.
    FA-Leu-Gly-Pro-Ala-OH TFA
  • HY-P5711
    NEMURI
    		Inhibitor
    NEMURI is an antimicrobial peptide with sleep-promoting effect.
    NEMURI
  • HY-P5611
    Maximin 7
    Maximin 7 is an antimicrobial peptide derived from toad Bombina maxima.
    Maximin 7
  • HY-12820R
    Sibofimloc (Standard)
    		Inhibitor
    Sibofimloc (Standard) is the analytical standard of Sibofimloc. This product is intended for research and analytical applications. Sibofimloc (Antibiotic-202) is a first-in-class, gut-restricted, orally active FimH adhesion inhibitor extracted from patent WO2014100158A1, Compound Example 202. Sibofimloc has anti-bacterial infective activity. Sibofimloc is developed for inflammatory bowel disease (IBD)[1][2].
    Sibofimloc (Standard)
  • HY-146263
    ThrRS-IN-3
    ThrRS-IN-3 (compound 36j) is a highly potent threonyl-tRNA synthetase (ThrRS) inhibitor, with an IC50 value of 19 nM and a Kd of 34 nM for Salmonella enterica ThrRS. ThrRS-IN-3 has antibacterial activities.
    ThrRS-IN-3
  • HY-N15075
    Espinomycin A2
    		Inhibitor
    Espinomycin A2 is a sixteen-membered macrolide antibiotic. Espinomycin A2 is active against Gram-positive bacteria.
    Espinomycin A2
  • HY-P1763
    Urechistachykinin II
    		Inhibitor
    Urechistachykinin II (Uru-TK II), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect.
    Urechistachykinin II
  • HY-116992R
    Chloroneb (Standard)
    		Inhibitor
    Chloroneb (Standard) is the analytical standard of Chloroneb. This product is intended for research and analytical applications. Chloroneb (Demosan) is a pesticide with fungicidal and plant-protective activities. Chloroneb can be used to detect organochlorine pesticide residues, showing good selectivity, stability and reproducibility. Chloroneb has been applied to the detection of licorice, cucumber, river water and soil samples with satisfactory results.
    Chloroneb (Standard)
  • HY-127155
    Kigamicin C
    		Inhibitor
    Kigamicin C is an anti-tumor antibiotic that selectively kills pancreatic cancer PANC-1 cells only in nutrient-poor conditions. Kigamicin C has antimicrobial activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).
    Kigamicin C
  • HY-151339
    Antitubercular agent-31
    		Inhibitor
    Antitubercular agent-31 (Compound 2) is an antitubercular agent with an MIC of 0.03 μM against M. tuberculosis H37Rv. Antitubercular agent-31 also inhibits DprE1 with an IC50 of 1.1 μM.
    Antitubercular agent-31
  • HY-141442
    Dihydronovobiocin
    		Inhibitor
    Dihydronovobiocin is a bacterial inhibitor and ATPase inhibitor that can bind to GyrB. Dihydronovobiocin can be used to study the interaction between coumarin antibiotics (such as Novobiocin, Chlorobiocin, and Coumermycin) and DNA gyrase. Dihydronovobiocin also has the potential to study bacterial infections.
    Dihydronovobiocin
  • HY-P11134
    Leucocin A
    		Inhibitor
    Leucocin A (LeuA), a 37-amino acid peptide, is a class II bacteriocin without Lanthionine (HY-135113). Leucocin A has potent anti-bacterial activity against gram-positive bacteria, such as Leuconostoc paramesenteroides and Lactobacillus sake with MICs of 69 and 39 nM, respectively. Leucocin A can be used for infectious diseases research.
    Leucocin A
  • HY-144382
    Glutamate-5-kinase-IN-2
    Glutamate-5-kinase-IN-2 (compound 54) is a potent glutamate-5-kinase (G5K) inhibitor with an MIC (minimum inhibitory concentration) of 4.2 μM. Glutamate-5-kinase-IN-2 shows G5K inhibition by promotes conformational changes at the L-glutamate binding site. Glutamate-5-kinase-IN-2 has the potential for the research of anti-TB agents.
    Glutamate-5-kinase-IN-2
  • HY-167816
    1,2-Diheneicosanoyl-sn-glycero-3-phosphocholine
    		Inhibitor
    1,2-Diheneicosanoyl-sn-glycero-3-phosphocholine (21:0 PC) is a surfactant with antibacterial activity. 1,2-Diheneicosanoyl-sn-glycero-3-phosphocholine can act in mucus to help prevent the spread of pathogens. 1,2-Diheneicosanoyl-sn-glycero-3-phosphocholine plays a protective role in biofilms, maintaining the health of organisms.
    1,2-Diheneicosanoyl-sn-glycero-3-phosphocholine
  • HY-155190
    Antitubercular agent-39
    		Inhibitor
    Antitubercular agent-39 (Compound P1) is a potent antitubercular agent. Antitubercular agent-39 is active against drug-resistant strains and drug-susceptible clinical isolates. Antitubercular agent-39 inhibits Mtb strain H37Rv with a MIC less than 1 μM.
    Antitubercular agent-39
Cat. No. Product Name / Synonyms Application Reactivity