2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

Related Products

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-147988
    DNA Gyrase-IN-5
    		Inhibitor
    DNA Gyrase-IN-5 (Compound 8I-w) is a potent DNA gyrase inhibitor with an IC50 of 0.10 μM. DNA Gyrase-IN-5 shows antibacterial activities against wild type and drug-resistant strains.
    DNA Gyrase-IN-5
  • HY-117870
    Ro 24-4383
    		Inhibitor
    Ro 24-4383 is a carbamate-linked dual action antibacterial agent.
    Ro 24-4383
  • HY-N12686
    Dichamanetin
    		Inhibitor
    Dichamanetin, a C-benzylated flavanone that can be isolated from Piper sarmentosum, is a potent antibacterial and anticancer agent. Dichamanetin displays antibacterial activity against a panel of Gram-positive strains, including resistant S. aureus strains with MIC values in the range of 1-7.5 μg/mL. Dichamanetin inhibits cancer cell growth by affecting ROS-related signaling components via mitochondrial-mediated apoptosis. Dichamanetin can be used for colon, prostate, breast cancer and infection research.
    Dichamanetin
  • HY-P5651
    PhD4
    		Inhibitor
    PhD4 is an antimicrobial peptide derived from monkey white blood cells. PhD4 has activity against bacteria and fungus Candida albicans.
    PhD4
  • HY-176519
    ANT2681
    		Inhibitor
    ANT2681 is a potent NDM inhibitor with a Ki value of 0.04 μM against NDM-1. ANT2681 also inhibits other MBLs, such as VIM-1 and IMP-1 with Ki values of 0.63 μM and 3.81 μM, respectively. ANT2681 can be used in combination with Meropenem (HY-13678) to inhibit infections caused by NDM-producing Enterobacteriaceae.
    ANT2681
  • HY-A0035
    Faropenem
    Faropenem is a potent and orally active beta-lactam antibiotic. Faropenem demonstrates broad-spectrum in vitro antimicrobial activity against many gram-positive and -negative aerobes and anaerobes. Faropenem is resistant to hydrolysis by nearly all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Faropenem is developed as an oral proagent, faropenem medoxomil, for the research of respiratory tract infections.
    Faropenem
  • HY-E70426A
    Polyphosphate Kinase, Propionibacterium shermanii
    Polyphosphate kinase (RsPPK; PPK), Propionibacterium shermanii is the Polyphosphate kinase (HY-E70426) derived from Propionibacterium shermanii. Polyphosphate kinase is a key enzyme in bacteria that catalyzes the reversible conversion between inorganic polyphosphate (polyP) and nucleoside phosphates (ATP/ADP/AMP, etc.). Polyphosphate kinase antagonizes the expression of virulence genes regulated by (p) ppGpp, PigR, MglA and SspA in Francisella tularensis. Polyphosphate kinase can be used in studies related to tularemia.
    Polyphosphate Kinase, Propionibacterium shermanii
  • HY-146327R
    PqsR/LasR-IN-1 (Standard)
    		Inhibitor
    Scopolamine butylbromide (Standard) is the analytical standard of Scopolamine butylbromide. This product is intended for research and analytical applications. 0
    PqsR/LasR-IN-1 (Standard)
  • HY-181283
    MSU-43557
    		Inhibitor
    MSU-43557 is a Mycobacterium abscessus MmpL3 (MAB_4508) inhibitor and bactericidal agent. MSU-43557 inhibits MmpL3 function, disrupts trehalose monomycolate synthesis, and reduces biofilm-associated Mycobacterium abscessus viability. MSU-43557 exerts bactericidal activity against intracellular Mycobacterium abscessus. MSU-43557 shows low eukaryotic cytotoxicity and low Mycobacterium abscessus resistance frequency. MSU-43557 can be used for the research of mycobacterium abscessus infection.
    MSU-43557
  • HY-P11471
    (K(C10)GGGRrRPC)2
    		Inhibitor
    (K(C10)GGGRrRPC)2 (Compound (C-C10)C-C) is a dimeric lipopeptide and antibacterial agent. (K(C10)GGGRrRPC)2 enhances the accumulation of ROS, inhibits the bacterial respiratory chain dehydrogenase activity. (K(C10)GGGRrRPC)2 exhibits significant inhibition of bacterial biofilm formation. (K(C10)GGGRrRPC)2 exhibits antimicrobial activity against Acinetobacter baumannii AB1901, A. baumannii AB1902, Pseudomonas aeruginosa 25349, Staphylococcus aureus 11011, with MICs of 4 μM, 8 μM, 4 μM, and 8 μM, respectively. (K(C10)GGGRrRPC)2 shows antimicrobial efficacy against E. coli ATCC 25922.
    (K(C10)GGGRrRPC)2
  • HY-N8388
    Collinin
    		Inhibitor
    Collinin is a anti-tubercular agent, it can be isolated from leaves of Z. schinifolium. Collinin has an excellent anti-tuberculosis effect against multidrug-resistant (MDR), extensively drug-resistant (XDR) strains.
    Collinin
  • HY-W010629S
    2-Chloroacetamide-d4
    2-Chloroacetamide-d4 is the deuterium labeled 2-Chloroacetamide. 2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase.
    2-Chloroacetamide-d<sub>4</sub>
  • HY-135759
    Cetraxate
    		Inhibitor
    Cetraxate is an orally active antiulcer Drug. Cetraxate increases the blood flow of gastric mucosal. Cetraxate increases the eradication of Helicobacter pylori in smokers when in combination with Omeprazole (HY-B0113),Amoxicillin (HY-B0467A), and Clarithromycin (HY-17508) .
    Cetraxate
  • HY-P5699
    Cyclopetide 2
    		Inhibitor
    Cyclopetide 2 (Compound 2) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 50 μg/mL.
    Cyclopetide 2
  • HY-113627
    Undecylprodigiosin
    		Inhibitor
    Undecylprodigiosin, a member of the family of prodiginines, is a potent antibiotic. Undecylprodigiosin can selectively induce apoptosis in human breast carcinoma cells independent of p53. Undecylprodigiosin shows immunosuppressive, anticancer properties and antimicrobial activities.
    Undecylprodigiosin
  • HY-14879S7
    Avibactam-13C5,15N sodium
    Avibactam-13C5,15N sodium (NXL-104-13C5,15N sodium) is the 13C- and 15N-labeled Avibactam (HY-14879). Avibactam (NXL-104) free acid is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively.
    Avibactam-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N sodium
  • HY-P5723
    Api137
    		Inhibitor
    Api137 is an antimicrobial peptide that interferes with bacterial growth by inhibiting translation. Api137 inhibits protein synthesis by trapping of release factors on the 70S ribosome following hydrolysis of the nascent polypeptide chain.
    Api137
  • HY-14648S1
    Dexamethasone-d5-1
    		Inhibitor
    Dexamethasone-d5-1 is deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.
    Dexamethasone-d<sub>5</sub>-1
  • HY-150699
    TXA6101
    		Inhibitor
    TXA6101 is a bacterial protein FtsZ (filamentous temperature-sensitive protein Z) inhibitor that inhibits bacterial division. TXA6101 has antimicrobial activity against MRSA isolates expressing either the G193D or G196S mutant FtsZ with the MIC value of 1 μg/mL, retains significant activity against the TXA707-resistant FtsZ mutant. TXA6101 can be used as a potential method against Gram-negative bacterial infections.
    TXA6101
  • HY-P11093
    Papiliocin
    		Inhibitor
    Papiliocin is a potent peptide antibiotic with both anti-inflammatory and antibacterial activities. Papiliocin is primarily active against Gram-negative bacteria. Papiliocin exhibits strong anti-inflammatory activity against cell, exerting its anti-inflammatory activity by inhibiting the production of NO and the secretion of TNF-α and MIP-2. Papiliocin participates in the innate defense response mechanism by inhibiting the Toll-like receptor pathway and NF-κB. Papiliocin induces apoptosis in fungal cells and increases the total level of intracellular ROS. Papiliocin acts as an effective antiseptic peptide in sepsis models. Papiliocin is useful in anti-inflammatory and antibacterial research.
    Papiliocin
Cat. No. Product Name / Synonyms Application Reactivity