DNA Gyrase-IN-5
DNA Gyrase-IN-5 (Compound 8I-w) is a potent DNA gyrase inhibitor with an IC50 of 0.10 μM. DNA Gyrase-IN-5 shows antibacterial activities against wild type and drug-resistant strains.
For research use only. We do not sell to patients.
- CAS No.: 2417016-23-8
- Formula: C25H15BrClN5
- Molecular Weight:500.78
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
IC50: 0.10 μM (DNA gyrase)[1]
DNA Gyrase-IN-5 (Compound 8I-w) shows antibacterial activities with IC50 values of 4.7, 7.0, 17.0, 13.5, 1.0, 25.3 and 47.8 μM against E. coli, E. coli E564, E. coli E68, E. coli E48, E. coli E109, Salmonella and S. aureus, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2417016-23-8
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Molecular Weight 500.78
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Formula C25H15BrClN5
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SMILES
N#CC1=C(/N=C/C2=C(C3=CC=C(Br)C=C3)NC4=C2C=CC=C4)N(C5=CC=C(Cl)C=C5)N=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)