2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-180240
    Antibacterial agent 308
    		Inhibitor
    Antibacterial agent 308 (Compound A25) is an antibacterial agent. Antibacterial agent 308 selectively targets bacterial membranes by binding phosphatidylethanolamine, thereby disrupting membrane polarization, elevating intracellular ROS levels. Antibacterial agent 308 shows significant anti-biofilm activity against S. aureus. Antibacterial agent 308 demonstrates potent anti-MRSA activity.
    Antibacterial agent 308
  • HY-123036
    Renierone
    		Inhibitor
    Renierone is an antibacterial metabolite found in the sponge Reniera sp..
    Renierone
  • HY-178740
    GI261520A
    		Inhibitor
    GI261520A is a egfr/erbb2 dual inhibitor. GI261520A inhibits PhoQ phosphorylation dose-dependently. GI261520A can downregulate the activity levels of PhoP/PhoQ. GI261520A inhibits pagC reporter expression levels with an IC50 of 3.2 μM. GI261520A inhibits PhoQc autokinase activtiy by 80%. GI261520A can permeate the eukaryotic plasmatic and vascular cell membranes and reach intravacuolar Salmonella to block intramacrophage proliferation.
    GI261520A
  • HY-N14030
    Coriolin C
    		Inhibitor
    Coriolin C has anti-Gram-positive bacteria, negative bacteria (weak), yeast and vaginal trichomoniasis activities. Coriolin C of 5 μg/mL can inhibit the growth of yoshida sarcoma 61.6%. Coriolin C has no inhibitory effect on Ehrlich ascites carcinoma in animals.
    Coriolin C
  • HY-N15071
    23-De(mycinosyloxy)tylosin
    		Inhibitor
    23-De(mycinosyloxy)tylosin is a macrolide antibiotic. 23-De(mycinosyloxy)tylosin has anti-Gram-positive bacteria and weak anti-Gram-negative bacteria and mycoplasma activity.
    23-De(mycinosyloxy)tylosin
  • HY-B2170AR
    Octenidine dihydrochloride (Standard)
    		Inhibitor
    Octenidine (dihydrochloride) (Standard) is the analytical standard of Octenidine (dihydrochloride). This product is intended for research and analytical applications. Octenidine dihydrochloride is an effective antiseptic compound for skin mucous membranes and wounds.
    Octenidine dihydrochloride (Standard)
  • HY-N8497
    Leoidin
    		Inhibitor
    Leoidin is an OATP1B1 and OATP1B3 inhibitor with Ki values of 0.08 and 1.84 μM，respectively. Leoidin inhibits sodium fluorescein uptake in CHO cells expressing the human OATP1B1 and OATP1B3. Leoidin is an antibacterial agent against both Gram-positive and Gram-negative pathogens. Leoidin inhibits phenylalanyl-tRNA synthetase (PheRS) (IC50= 42 μM) and inhibits protein synthesis in bacterial. Leoidin can be isolated from L. gangaleoides.
    Leoidin
  • HY-N14202
    Maridomycin V
    		Inhibitor
    Maridomycin V is a macrolide antibiotic. Maridomycin Vhas the activity against Gram-positive bacteria and mycoplasma. Maridomycin V has the effect of protecting Gram-positive bacterial infection mice.
    Maridomycin V
  • HY-183551
    Antitubercular agent-59
    		Inhibitor
    Antitubercular agent-59 is an orally active antitubercular agent with an IC50 of 51 nM against Mycobacterium tuberculosis H37Rv. Antitubercular agent-59 inhibits growth of Bedaquiline (HY-14881)-resistant Rv0678G12C mutant strains. Antitubercular agent-59 exerts bactericidal activity in chronic tuberculosis mouse models with 1-Aminobenzotriazole (HY-103389) coadministration.
    Antitubercular agent-59
  • HY-106575
    Nifurzide
    		Inhibitor
    Nifurzide, a nitrofuran derivative, is used as an intestinal antiinfectious agent. Nifurzide shows strong bactericidal effect.
    Nifurzide
  • HY-B0368B
    D-Captopril
    D-Captopril is a NDM-1 inhibitor and a competitive BlaB inhibitor, with an IC50 value of 21.8 µM against NDM-1 and a Ki of 70-100 µM against BlaB. D-Captopril synergistically reduces the minimum inhibitory concentration of Meropenem (HY-13678) against NDM-1-expressing bacteria. D-Captopril binds to BcII via its thiolate sulfur atom and carboxylate group, altering metal ion occupancy and modulating Cd2+ binding affinity. D-Captopril can be used in the research of neonatal meningitis, sepsis and bacterial infections.
    D-Captopril
  • HY-N14526
    Octacosamicin A
    		Inhibitor
    Octacosamicin A has the function of resisting bacterium, yeast, and filamentous fungus, but the function of resisting bacterium is weak.
    Octacosamicin A
  • HY-N3640
    Crenatine
    		Inhibitor
    Crenatine is an antibacterial agent. Crenatine is more effective against Gram-positive than Gram-negative bacteria.
    Crenatine
  • HY-14743R
    Golotimod (Standard)
    		Inhibitor
    Golotimod (Standard) is the analytical standard of Golotimod. This product is intended for research and analytical applications. Golotimod (SCV-07), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod (SCV-07) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod (SCV-07) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2).
    Golotimod (Standard)
  • HY-N14653
    Glysperin A
    		Inhibitor
    Glysperin A has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity.
    Glysperin A
  • HY-124508
    Lambertellin
    		Inhibitor
    Lambertellin is an effective antibiotic that can be used as a bactericide and as a fungicide. Lambertellin exerts its anti-inflammatory effect in LPS (HY-D1056)-stimulated RAW 264.7 macrophage cells by modulating the activation of the MAPK and NF-κB signaling pathways.
    Lambertellin
  • HY-169635
    Mycobacterium Tuberculosis-IN-6
    		Inhibitor
    Mycobacterium Tuberculosis-IN-6 (compound b1) is an inhibitor of Mycobacterium tuberculosis enoyl reductase InhA, with IC50 of 7.74 μM. Mycobacterium Tuberculosis-IN-6 can be used for antibacterial research.
    Mycobacterium Tuberculosis-IN-6
  • HY-N14881
    Monorden E
    		Inhibitor
    Monorden E has the effect of arresting the cell cycle of Jurket cells in G1 and G2/M phases. Monorden E has anti-Aspergillus niger activity.
    Monorden E
  • HY-183711
    Antibacterial agent 344
    		Inhibitor
    Antibacterial agent 344 is an antibacterial agent with potent biofilm inhibition (IC50 = 0.27 μM). Antibacterial agent 344 inhibits heme oxygenase (HemO), impairs iron homeostasis, virulence factor production, and motility. Antibacterial agent 344 synergizes with Ciprofloxacin (HY-B0356) and Tobramycin (HY-B0441), enhancing their efficacy and delaying the development of resistance. Antibacterial agent 344 improves bacterial-infected Galleria mellonella survival, and reduces bacterial load in mice wounds. Antibacterial agent 344 can be used for the research of Pseudomonas aeruginosa infections.
    Antibacterial agent 344
  • HY-107053
    BC-1175
    		Inhibitor
    BC-1175 (CB-181963) is a novel cephalosporin and antibacterial agent. CB-181963 displays strong binding to altered PBP 2a. CB-181963 demonstrates marked efficacy against MRSA, Klebsiella pneumoniae, Streptococcus pneumoniae, and Escherichia coli.
    BC-1175
Cat. No. Product Name / Synonyms Application Reactivity