2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

Related Products

PDF 48.35 MB

Endogenous metabolites refer to the collective set of small-molecule chemical substances present within organelles, cells, organs, biological fluids, or entire organisms; their molecular weights are typically less than 1500 Da. These endogenous metabolites—including lipids, amino acids, short peptides, nucleic acids, carbohydrates, alcohols, and organic acids—not only participate in signal transduction governing genomic function but also receive upstream signals from the environment, thereby bridging the interrelationships among genotype, environment, and phenotype. Based on their biological functions, microbial endogenous metabolites can be broadly classified into two categories: primary metabolites and secondary metabolites. Primary metabolites are the core molecules essential for supporting microbial growth and proliferation; they serve to provide energy to the microbes or act as precursors and cofactors for the synthesis of biological macromolecules. In contrast, microbial secondary metabolites are a class of low-molecular-weight products that are not strictly essential for microbial growth. Nevertheless, microbial secondary metabolites include numerous substances—such as antibiotics, anti-tumor agents, and cholesterol-lowering agents—that are of critical importance to human health[1][2][3]. Furthermore, the metabolome of a biological organism is influenced by a variety of endogenous factors, including age, sex, body composition, genetic background, and underlying pathological states. The small-molecule metabolites within an organism are diverse and highly distinct; their levels are typically subject to the synergistic regulation of a vast array of enzymes and transport proteins, undergoing processes of synthesis, transformation, degradation, and compartmentalized distribution. Metabolomics research based on endogenous metabolites has been widely applied in the fields of metabolic disorders, neurodegenerative diseases, cancer, cardiovascular diseases, and infectious diseases, where these metabolites hold potential utility as biomarkers or therapeutic targets[1][2][3].

Endogenous Metabolite Isoform Specific Products:

Endogenous Metabolite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1945R
    DEHP (Standard)
    DEHP (Standard) is the analytical standard of DEHP. This product is intended for research and analytical applications. DEHP (Bis(2-ethylhexyl) phthalate) is a widely used plasticizer, which has orally active. DEHP can produce a wide spectrum of toxic effects on organisms including neurotoxicity, liver toxicity, immunotoxicity, and reproductive toxicity.
    DEHP (Standard)
  • HY-128425R
    N-​Carbamoyl-​DL-​aspartic acid (Standard)
    N-​Carbamoyl-​DL-​aspartic acid (Standard) (Ureidosuccinic acid (Standard)) is the analytical standard of N-​Carbamoyl-​DL-​aspartic acid (HY-128425). This product is intended for research and analytical applications. N-​Carbamoyl-​DL-​aspartic acid is a precursor of nucleic acid pyrimidines. N-​Carbamoyl-​DL-​aspartic acid has antitumor activities.
    N-​Carbamoyl-​DL-​aspartic acid (Standard)
  • HY-D0184R
    2'-Deoxycytidine (Standard)
    Cefaclor (monohydrate) (Standard) is the analytical standard of Cefaclor (monohydrate). This product is intended for research and analytical applications. Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections.
    2'-Deoxycytidine (Standard)
  • HY-113527R
    TRIA-662 (Standard)
    TRIA-662 (Standard) is the analytical standard of TRIA-662. This product is intended for research and analytical applications. TRIA-662 (1-Methylnicotinamide chloride) is an endogenous metabolite. TRIA-662 shows antithrombotic and anti-inflammatory activities.
    TRIA-662 (Standard)
  • HY-N0210R
    D-Galactose (Standard)
    D-Galactose (Standard) is the analytical standard of D-Galactose. This product is intended for research and analytical applications. D-Galactose is a natural aldohexose and C-4 epimer of glucose.
    D-Galactose (Standard)
  • HY-121883S
    Lignoceric acid-d47
    		98.4%
    Lignoceric acid-d47 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research.
    Lignoceric acid-d<sub>47</sub>
  • HY-W013636S1
    2-Ketoglutaric acid-d4
    2-Ketoglutaric acid-d4 (Alpha-Ketoglutaric acid-d4) is the deuterium labeled 2-Ketoglutaric acid (HY-W013636). 2-Ketoglutaric acid Sodium is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC50=15 mM).
    2-Ketoglutaric acid-d<sub>4</sub>
  • HY-N12777
    Coixenolide
    		99.93%
    Coixenolide can be isolated from coix seeds, and exhibits anti-inflammatory, anti-tumor and pain-reducing activities. Coixenolide stimulates the lung, heart, striated and smooth muscles at low doses, while inhibits at high doses. Coixenolide dilates pulmonary veins and improves pulmonary blood circulation. Coixenolide can also be used as nutraceuticals and functional foods. Coixenolide enhances the prodcutionof mycelia biomass and polysaccharides when added to the media of submerged culture of G. lucidum. Coixenolide affects the synthesis level of phosphoglucose isomerase and α-phosphoglucomutase.
    Coixenolide
  • HY-N2041R
    Myristic acid (Standard)
    Myristic acid (Standard) is the analytical standard of Myristic acid. This product is intended for research and analytical applications. Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties.
    Myristic acid (Standard)
  • HY-113131
    Dihydroxyacetone phosphate
    		99.90%
    Dihydroxyacetone phosphate (DHPA), a derivative of Dihydroxyacetone (DHA), is an important intermediate that participates in key pathways including glycolysis, lipid biosynthesis, and the plant Calvin cycle. Dihydroxyacetone phosphate can be used as a substrate and metabolic marker in biochemical research.
    Dihydroxyacetone phosphate
  • HY-Y0337S2
    L-Cysteine-3-13C
    		98.5%
    L-Cysteine-3-13C is the 13C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans.
    L-Cysteine-3-<sup>13</sup>C
  • HY-127061
    Palmitoleoyl ethanolamide
    		99.77%
    Palmitoleoyl ethanolamide (POEA) is an endogenous fatty amide with biological activity.
    Palmitoleoyl ethanolamide
  • HY-168761
    N-Cholyl-L-alanine
    		99.2%
    N-Cholyl-L-alanine is a bile acid amidate, which is found in human fecal samples.
    N-Cholyl-L-alanine
  • HY-B2156R
    Menaquinone-4 (Standard)
    Menaquinone-4 (Standard) is the analytical standard of Menaquinone-4. This product is intended for research and analytical applications. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.
    Menaquinone-4 (Standard)
  • HY-I0660R
    Picolinic acid (Standard)
    Picolinic acid (Standard) is the analytical standard of Picolinic acid. This product is intended for research and analytical applications. Picolinic acid (PCL 016) is a topical antiviral agent, which inhibits adenovirus replication in rabbits.
    Picolinic acid (Standard)
  • HY-W016568
    Isoxanthopterin
    		99.68%
    Isoxanthopterin is a heterocyclic compound belonging to the pteridine family and its activity is mainly reflected in its optical properties. Isoxanthopterin can form a reflective layer in the eyes of animals, enhancing visual function. The main regulatory mechanism of isoxanthopterin involves its ability to form a crystalline structure within organisms, which achieves a high refractive index through specific hydrogen bonding patterns and molecular arrangements. Isoxanthopterin can be used for research in materials science and optical engineering.
    Isoxanthopterin
  • HY-B2227BS3
    L-Lactic acid-13C-1 sodium (20% w/w in water)
    		98.7%
    L-Lactic acid-13C1 (L-E-270-13C1) sodium (20% in water) is the 13C-labeled L-Lactic acid sodium (HY-W040233). L-lactate Sodium is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid Sodium has antiproliferative activityy.
    L-Lactic acid-<sup>13</sup>C-1 sodium (20% w/w in water)
  • HY-B1331
    Cyromazine
    		99.79%
    Cyromazine (CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects. Cyromazine reduced the number of germ cells by interfering with the Ecdysone (HY-N0179) signaling pathway. Cyromazine induces renal toxicity attenuated and restored by green tea extract in rats.
    Cyromazine
  • HY-P1032S2
    Angiotensin I-13C6,15N (human, mouse, rat) TFA
    		99.76%
    Angiotensin I-13C6,15N (human, mouse, rat) TFA is 13C and 15N labeled Angiotensin I (human, mouse, rat) TFA. Angiotensin I-13C6,15N (human, mouse, rat) TFA is a precursor of angiotensin II and is cleaved into angiotensin II by angiotensin converting enzyme (ACE).
    Angiotensin I-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N (human, mouse, rat) TFA
  • HY-W016389
    2-Hydroxyfluorene
    		99.83%
    2-Hydroxyfluorene (2-OHFLU) is a polycyclic aromatic hydrocarbon metabolite. 2-Hydroxyfluorene is positively associated with cardiovascular disease (CVD) and hyperlipidemia.
    2-Hydroxyfluorene
Cat. No. Product Name / Synonyms Application Reactivity
Endogenous Metabolite Isoform Comparison

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.