Dihydroxyacetone phosphate (Synonyms: DHAP)

Cat. No.: HY-113131: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Dihydroxyacetone phosphate (DHPA), a derivative of Dihydroxyacetone (DHA), is an important intermediate that participates in key pathways including glycolysis, lipid biosynthesis, and the plant Calvin cycle. Dihydroxyacetone phosphate can be used as a substrate and metabolic marker in biochemical research.

It is advisable to consider the salt form (Dihydroxyacetone phosphate hemimagnesium hydrate) that retains the same biological activity.

For research use only. We do not sell to patients.

Dihydroxyacetone phosphate Chemical Structure

CAS No. : 57-04-5

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5 mg		Ask For Quote & Lead Time
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25 mg		Ask For Quote & Lead Time
50 mg		Ask For Quote & Lead Time
100 mg		Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

Other In-stock Forms of Dihydroxyacetone phosphate:

Dihydroxyacetone phosphate hemimagnesium hydrate Dihydroxyacetone phosphate dilithium

Other Forms of Dihydroxyacetone phosphate:

Dihydroxyacetone phosphate hemimagnesium hydrate In-stock
Dihydroxyacetone phosphate dilithium In-stock

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Human Endogenous Metabolite Microbial Metabolite

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

Human Endogenous Metabolite

In Vitro

Dihydroxyacetone phosphate can be used in fructose metabolism, triose and glycation research^[1].
Dihydroxyacetone phosphate has potential glycating effects to form advanced glycation end products (AGEs)^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

Molecular Weight

170.06

Formula

C₃H₇O₆P

CAS No.

57-04-5

Appearance

Oil

Color

Colorless to light yellow

SMILES

O=C(COP(O)(O)=O)CO

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Microorganisms

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (588.03 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.8803 mL	29.4014 mL	58.8028 mL
5 mM	1.1761 mL	5.8803 mL	11.7606 mL
10 mM	0.5880 mL	2.9401 mL	5.8803 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.9%

Select Batch:

Data Sheet (270 KB) SDS (252 KB)

COA (244 KB)

Handling Instructions (2659 KB)

References

[1]. Shimakawa G, et al. The Calvin cycle inevitably produces sugar-derived reactive carbonyl methylglyoxal during photosynthesis: a potential cause of plant diabetes. Plant Cell Physiol. 2014 Feb;55(2):333-40. [Content Brief]

[2]. Qungang Qi,et al. The role of the triose-phosphate shuttle and glycolytic intermediates in fatty-acid and glycerolipid biosynthesis in pea root plastids.S.A. Planta (1994) 194: 193.

[3]. Ahmad S, et al. Inhibitory effect of metformin and pyridoxamine in the formation of early, intermediate and advanced glycation end-products. PLoS One. 2013 Sep 4;8(9):e72128. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	5.8803 mL	29.4014 mL	58.8028 mL	147.0069 mL
	5 mM	1.1761 mL	5.8803 mL	11.7606 mL	29.4014 mL
	10 mM	0.5880 mL	2.9401 mL	5.8803 mL	14.7007 mL
	15 mM	0.3920 mL	1.9601 mL	3.9202 mL	9.8005 mL
	20 mM	0.2940 mL	1.4701 mL	2.9401 mL	7.3503 mL
	25 mM	0.2352 mL	1.1761 mL	2.3521 mL	5.8803 mL
	30 mM	0.1960 mL	0.9800 mL	1.9601 mL	4.9002 mL
	40 mM	0.1470 mL	0.7350 mL	1.4701 mL	3.6752 mL
	50 mM	0.1176 mL	0.5880 mL	1.1761 mL	2.9401 mL
	60 mM	0.0980 mL	0.4900 mL	0.9800 mL	2.4501 mL
	80 mM	0.0735 mL	0.3675 mL	0.7350 mL	1.8376 mL
	100 mM	0.0588 mL	0.2940 mL	0.5880 mL	1.4701 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Dihydroxyacetone phosphate Related Classifications

Metabolic Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dihydroxyacetone57-04-5DHAPEndogenous MetaboliteBiochemical Assay ReagentsInhibitorinhibitorinhibit

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