2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.

Liposome Related Products (387):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-148842
    C14-4
    		99.01%
    C14-4 is an ionizable lipid for lipid nanoparticles (LNPs) formulation. C14-4 was identified for its potent transfection and low cytotoxicity.
    C14-4
  • HY-109541
    1,2-Dimyristoyl-sn-glycero-3-phosphocholine
    		≥98.0%
    1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine is used for the study of lipid monolayers and bilayers.
    1,2-Dimyristoyl-sn-glycero-3-phosphocholine
  • HY-113217
    Cholesteryl oleate
    		≥98.0%
    Cholesteryl oleate is an esterified form of Cholesterol. Cholesteryl oleate can be used in the generation of solid lipid nanoparticle (SLN, a nanoparticle-based method for gene therapy).
    Cholesteryl oleate
  • HY-144004
    DSPE-PEG2000-Mal ammonium
    DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents.
    DSPE-PEG2000-Mal ammonium
  • HY-137500
    NT1-014B
    		98.12%
    NT1-014B is a potent NT1-lipidoid encapsulated AmB (amphotericin B). NT1-014B dopes the NT-lipidoids into BBB-impermeable lipid nanoparticles (LNPs) gave the LNPs the ability to cross the BBB. NT1-014B enhances brain delivery through intravenous injection.
    NT1-014B
  • HY-147332
    TCL053
    		≥98.0%
    TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle.
    TCL053
  • HY-130462
    1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
    		99.98%
    1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers.
    1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
  • HY-131119
    Dimethyldioctadecylammonium bromide
    		≥99.0%
    Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.
    Dimethyldioctadecylammonium bromide
  • HY-W590532
    306-O12B
    		99.90%
    306-O12B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs).
    306-O12B
  • HY-148855
    OF-C4-Deg-Lin
    OF-C4-Deg-Lin is an ionizable lipid with varied linker lengths. OF-C4-Deg-Lin can be used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA.
    OF-C4-Deg-Lin
  • HY-139298
    L319
    		≥98.0%
    L319 is an ionizable cationic lipidoid and can be used for synthetic liposomes, from the patent WO-2011153493-A2, compound 1.
    L319
  • HY-137499
    NT1-O12B
    NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination.
    NT1-O12B
  • HY-154831
    C22-Ceramide
    		≥98.0%
    C22-Ceramide (Cer d18:1/22:0) is an endogenous bioactive sphingolipid. C22-Ceramide reduces the propensity of C16-ceramide channel formation in isolated rat liver mitochondria and in liposomes.
    C22-Ceramide
  • HY-137131
    DC-Chol hydrochloride
    		≥98.0%
    DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner.
    DC-Chol hydrochloride
  • HY-W440896
    DSPE-PEG-SH, MW 2000
    		99.39%
    DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.
    DSPE-PEG-SH, MW 2000
  • HY-W441007
    DSPE-Mal
    DSPE-MAL is a thiol reactive a phospholipid compound. DSPE-MAL has two saturated fatty acids and can self-assemble in water to form lipid bilayer. DSPE-MAL can be used to prepare liposomes as agent nanocarrier.
    DSPE-Mal
  • HY-140736
    DSPE-PEG-Biotin, MW 2000
    DSPE-PEG-Biotin, MW 2000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
    DSPE-PEG-Biotin, MW 2000
  • HY-W440832
    DSPE-PEG-Azide, MW 2000
    		≥98.0%
    DSPE-PEG-Azide, MW 2000 is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery. DSPE-PEG-Azide, MW 2000 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    DSPE-PEG-Azide, MW 2000
  • HY-144009
    DSPE-PEG-Folate, MW 3350
    DSPE-PEG-Folate, MW 3350 is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research.
    DSPE-PEG-Folate, MW 3350
  • HY-112772A
    98N12-5
    		≥98.0%
    98N12-5 is a novel multi-tail ionizable lipids that has been used for efficient in vivo siRNA–delivery to the liver.
    98N12-5