NT1-O14B
Based on 2 publication(s) in Google Scholar
NT1-O14B is a tryptamine-derived lipidoid. NT1-O14B incorporates NT-lipidoid into BBB-impermeable lipid nanoparticles (LNPs), enabling the LNPs to cross the BBB. NT1-O14B enhances brain delivery via intravenous injection. NT1-O14B can be used in ischemic stroke research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.43%
- CAS 番号: 2739805-64-0
- 分子式: C40H68N2O4S4
- 分子量:769.24
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 NT1-O14B
More
生物活性
NT1-014B 用于制备平均粒径在 140-170 nm 的 LNP3[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2739805-64-0
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性状 Viscous Liquid
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分子量 769.24
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分子式 C40H68N2O4S4
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Color Colorless to light yellow
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SMILES
O=C(CCN(CCC(OCCSSCCCCCCCCCC)=O)CCC1=CNC2=C1C=CC=C2)OCCSSCCCCCCCCCC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Acta Biomater
Tuning the polyethylene glycol-lipid anchor length of lipid nanoparticles to enhance brain-targeted siRNA delivery. [Abstract]2025 Oct 11:S1742-7061(25)00762-7. PMID: 41083040 -
Mol Pharm
2026 May 4;23(5):2944-2954. PMID: 41931102
溶剤 & 溶解度
DMSO : 150 mg/mL (195.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Ma F, et al. Neurotransmitter-derived lipidoids (NT-lipidoids) for enhanced brain delivery through intravenous injection. Sci Adv. 2020 Jul 24;6(30):eabb4429. [Content Brief]
[2]. Jia Y, et al. Nose-to-Brain Delivery of Circular RNA SCMH1-Loaded Lipid Nanoparticles for Ischemic Stroke Therapy. Adv Mater. 2025 Mar 27:e2500598. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3000 mL | 6.4999 mL | 12.9998 mL | 32.4996 mL |
| 5 mM | 0.2600 mL | 1.3000 mL | 2.6000 mL | 6.4999 mL | |
| 10 mM | 0.1300 mL | 0.6500 mL | 1.3000 mL | 3.2500 mL | |
| 15 mM | 0.0867 mL | 0.4333 mL | 0.8667 mL | 2.1666 mL | |
| 20 mM | 0.0650 mL | 0.3250 mL | 0.6500 mL | 1.6250 mL | |
| 25 mM | 0.0520 mL | 0.2600 mL | 0.5200 mL | 1.3000 mL | |
| 30 mM | 0.0433 mL | 0.2167 mL | 0.4333 mL | 1.0833 mL | |
| 40 mM | 0.0325 mL | 0.1625 mL | 0.3250 mL | 0.8125 mL | |
| 50 mM | 0.0260 mL | 0.1300 mL | 0.2600 mL | 0.6500 mL | |
| 60 mM | 0.0217 mL | 0.1083 mL | 0.2167 mL | 0.5417 mL | |
| 80 mM | 0.0162 mL | 0.0812 mL | 0.1625 mL | 0.4062 mL | |
| 100 mM | 0.0130 mL | 0.0650 mL | 0.1300 mL | 0.3250 mL |
NT1-O14B 関連分類
HY-137500 関連分類
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