1. Metabolic Enzyme/Protease
  2. Liposome
  3. NT1-014B

NT1-014B is a potent NT1-lipidoid encapsulated AmB (amphotericin B). NT1-014B dopes the NT-lipidoids into BBB-impermeable lipid nanoparticles (LNPs) gave the LNPs the ability to cross the BBB. NT1-014B enhances brain delivery through intravenous injection.

For research use only. We do not sell to patients.

NT1-014B Chemical Structure

NT1-014B Chemical Structure

CAS No. : 2739805-64-0

Size Price Stock Quantity
Solid or liquid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 59 In-stock
Solution
10 mM * 1 mL in DMSO USD 59 In-stock
Solid or liquid
5 mg USD 50 In-stock
10 mg USD 70 In-stock
25 mg USD 140 In-stock
50 mg USD 250 In-stock
100 mg USD 450 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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  • Purity & Documentation

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Description

NT1-014B is a potent NT1-lipidoid encapsulated AmB (amphotericin B). NT1-014B dopes the NT-lipidoids into BBB-impermeable lipid nanoparticles (LNPs) gave the LNPs the ability to cross the BBB. NT1-014B enhances brain delivery through intravenous injection[1].

Molecular Weight

769.24

Formula

C40H68N2O4S4

CAS No.
Appearance

Viscous Liquid

Color

Colorless to light yellow

SMILES

O=C(CCN(CCC(OCCSSCCCCCCCCCC)=O)CCC1=CNC2=C1C=CC=C2)OCCSSCCCCCCCCCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 150 mg/mL (195.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3000 mL 6.4999 mL 12.9998 mL
5 mM 0.2600 mL 1.3000 mL 2.6000 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3000 mL 6.4999 mL 12.9998 mL 32.4996 mL
5 mM 0.2600 mL 1.3000 mL 2.6000 mL 6.4999 mL
10 mM 0.1300 mL 0.6500 mL 1.3000 mL 3.2500 mL
15 mM 0.0867 mL 0.4333 mL 0.8667 mL 2.1666 mL
20 mM 0.0650 mL 0.3250 mL 0.6500 mL 1.6250 mL
25 mM 0.0520 mL 0.2600 mL 0.5200 mL 1.3000 mL
30 mM 0.0433 mL 0.2167 mL 0.4333 mL 1.0833 mL
40 mM 0.0325 mL 0.1625 mL 0.3250 mL 0.8125 mL
50 mM 0.0260 mL 0.1300 mL 0.2600 mL 0.6500 mL
60 mM 0.0217 mL 0.1083 mL 0.2167 mL 0.5417 mL
80 mM 0.0162 mL 0.0812 mL 0.1625 mL 0.4062 mL
100 mM 0.0130 mL 0.0650 mL 0.1300 mL 0.3250 mL
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NT1-014B Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
NT1-014B
Cat. No.:
HY-137500
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